Research output per year
Research output per year
Ian obtained a B.Sc in Chemistry from the University of Exeter and subsequently a PhD in Radiation Biology from Manchester University where he is now Professor of Pharmacy. Ian secured continuous programme grant support from the Medical Research Council between 1981 and 2010 and in addition, secured sustantive funding from the cancer charities and industry. He currently leads a small team of post-graduates and research associates and the focus of their research is twofold; 1/ to enhance the effects of radiotherapy by using molecularly targeted drugs and 2/ to exploit tumour energy metabolism to improve cancer therapy. In 2015 Ian was awarded the Weiss Medal at the quadrennial International Congress for Radiation Research for contributions to and achievements in radiation research.
50% of all cancer patients are treated with radiotherapy and yet this method of treatment is only effective in curing a fraction of these patients. One of the contributory factors to tumour resistance to radiotherapy is the presence of cells in the tumour that are starved of oxygen. These so-called hypoxic cells are not only resistant to radiotherapy but also chemotherapy. Tumours with a large number of hypoxic cells are often more malignant and have a greater tendency to metastasise. Thus, the presence of hypoxic cells in tumours is a major problem for therapy. Ian's group has for the last 30 years carried out research with the overall aim of overcoming this hypoxia problem.
The overall expertise of the group is:
Current projects include:
Funding for work in the Stratford lab currently comes from CR-UK, NIHR and the Pharmaceutical Industry.
PHAR40100 Option 2: Cancer Biology and Therapy
PHAR20100 The Medicine: Medicinal Chemistry lectures
PHAR20300 The Patient: Cancer lectures
PHAR10300 The Patient: Cancer lectures
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Stratford, I. (Participant), Williams, K. (Participant), West, C. (Participant), (Participant), (Participant), Eustace, A. (Participant) & (Participant)
Impact: Health impacts
Arthurs, C. L. (Contributor), Raftery, J. (Contributor), Whitby, H. L. (Contributor), Whitehead, R. (Contributor), Wind, N. S. (Contributor) & Stratford, I. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2008
DOI: 10.5517/ccp5jdr, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccp5jdr&sid=DataCite
Dataset
Parker, L. L. (Contributor), Lacy, S. M. (Contributor), Farrugia, L. J. (Contributor), Evans, C. (Contributor), Robins, D. J. (Contributor), O'Hare, C. C. (Contributor), Hartley, J. A. (Contributor), Jaffar, M. (Contributor) & Stratford, I. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2006
DOI: 10.5517/ccnfcjy, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccnfcjy&sid=DataCite
Dataset
Alnabulsi, S. (Contributor), Hussein, B. H. K. (Contributor), Santina, E. (Contributor), Alsalahat, I. (Contributor), Kadirvel, M. (Contributor), Magwaza, R. (Contributor), Bryce, R. (Contributor), Schwalbe, C. H. (Contributor), Baldwin, A. (Contributor), Russo, I. (Contributor), Stratford, I. (Contributor) & Freeman, S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2018
DOI: 10.5517/ccdc.csd.cc1zbw6d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zbw6d&sid=DataCite
Dataset
Arthurs, C. L. (Contributor), Morris, G. (Contributor), Piacenti, M. (Contributor), Pritchard, R. (Contributor), Stratford, I. (Contributor), Tatic, T. (Contributor), Whitehead, R. (Contributor), Williams, K. F. (Contributor) & Wind, N. S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011
DOI: 10.5517/cctntkt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cctntkt&sid=DataCite
Dataset
Christou, S. (Contributor), Edwards, A. C. (Contributor), Stratford, I. (Contributor) & Whitehead, R. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2014
DOI: 10.5517/cc11zylk, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11zylk&sid=DataCite
Dataset