Personal profile
Overview
Professor of Chronic Disease Genetics
Head of School, School of Biological Science, FBMH
Lead, Arthritis Research UK Centre for Genetics and Genomics
Research Theme Lead for Prevention of disease and the complications of treatment, NIHR Manchester Musculoskeletal Biomedical Research Unit
Honorary Research Principal Investigator, Central Manchester & Manchester Children's University Hospital, NHS Trust
I&R Domain, Academic Lead, Manchester Academic Health Science Centre Manchester
Memberships of committees and professional bodies
Research interests
Genetics and genomics: studies on the genetic contribution to a range of rheumatological disorders but with a specific focus on inflammatory joint disease. More
I am Research Theme Lead for the Prevention of disease and the complications of treatment research at the NIHR Manchester Musculoskeletal Biomedical Research Unit.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
Fingerprint
- 1 Similar Profiles
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Association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis-related calcinosis
Duffus, K., López-Isac, E., Teruel, M., Simeón, C. P., Carreria, P., Ortego-Centeno, N., Vicente, E., Worthington, J., Herrick, A. L. & Martin, J., Jul 2019, In: Rheumatology (United Kingdom). 58, 7, p. 1299-1301 3 p.Research output: Contribution to journal › Letter › peer-review
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Author Correction: Genotypic variability-based genome-wide association study identifies non-additive loci HLA-C and IL12B for psoriasis (Journal of Human Genetics, (2018), 63, 3, (289-296), 10.1038/s10038-017-0350-6)
Wei, W. H., Massey, J., Worthington, J., Barton, A. & Warren, R. B., 23 May 2019, In: Journal of Human Genetics.Research output: Contribution to journal › Commentary/debate › peer-review
Open Access -
Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases
Martin, P., Ding, J., Duffus, K., Gaddi, V., Mcgovern, A., Ray-Jones, H., Yarwood, A., Worthington, J., Barton, A. & Orozco, G., 15 May 2019, In: Annals Of Rheumatic Diseases. 78, p. 1127-1134Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 1 Dec 2019, In: Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases
Acosta-Herrera, M., Kerick, M., Gonzalez-Serna, D., Wijmenga, C., Franke, A., Gregersen, P. K., Padyukov, L., Worthington, J., Vyse, T., Alarcón-Riquelme, M. E., Mayes, M. D. & Martin, J., 14 Feb 2019, In: Annals Of Rheumatic Diseases. 78, p. 311-319 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile229 Downloads (Pure)
Projects
- 1 Finished
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Arthritis Research UK Centre of Excellence in the Genetics of Rheumatic Diseases.
Worthington, J. (PI), Barton, A. (CoI), Black, G. (CoI), Crow, Y. (CoI), Eyre, S. (CoI), Raychaudhuri, S. (CoI) & Thomson, W. (CoI)
1/08/13 → 31/07/18
Project: Research