Jenny H Humphreys

2025

Mortality Rates in Children, Young People, and Young Adults with JIA: an observational study using the Clinical Practice Research Datalink (CPRD)

Kearsley-Fleet, L., Shaw, N., Leslie, J., Johnson, M., Wedderburn, L. R., Hyrich, K. L. & Humphreys, J. H., 1 Jun 2025, In: EULAR Rheumatology Open. 1, 2, p. 39-44

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Can the General Public Be a Proxy for an “At-Risk” Group in a Patient Preference Study? A Disease Prevention Example in Rheumatoid Arthritis

DiSantostefano, R. L., Simons, G., Englbrecht, M., Humphreys, J. H., Bruce, I. N., Bywall, K. S., Radawski, C., Raza, K., Falahee, M. & Veldwijk, J., Feb 2024, In: Medical decision making. 44, 2, p. 189-202 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Using polygenic risk scores to aid diagnosis of patients with early inflammatory arthritis: results from the Norfolk Arthritis Register

Hum, R. M., Sharma, S., Stadler, M., Viatte, S., Ho, P., Nair, N., Shi, C., Yap, C. F., Soomro, M., Plant, D., Humphreys, J., Macgregor, A., Yates, M., Verstappen, S., Barton, A., Bowes, J. & NOAR collaborators, 17 Jan 2024, (E-pub ahead of print) In: Arthritis and Rheumatology.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Socioeconomic deprivation is associated with reduced response and lower treatment persistence with TNF inhibitors in rheumatoid arthritis

Zhao, S. S., Rogers, K., Kearsley-Fleet, L., Watson, K., Bosworth, A., Galloway, J., Verstappen, S., Plant, D., BSRBR-RA Contributors Group, BRAGGSS, Barton, A., Hyrich, K. L. & Humphreys, J. H., 2 Jun 2023, In: Rheumatology.

Research output: Contribution to journal › Article › peer-review

Open Access

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The epidemiology of psoriatic arthritis in the UK: a health intelligence analysis of UK Primary Care Electronic Health Records 1991-2020

Druce, K. L., Yimer, B. B., Humphreys, J., Njuki, L. N., Bourke, D., Li, M., Ellis, B., Zhang, Y., Bravo, R., Hyrich, K. L., Verstappen, S. M. M., Dixon, W. G. & McBeth, J., 2 Nov 2023, (E-pub ahead of print) In: Rheumatology (Oxford, England). kead586.

Research output: Contribution to journal › Article › peer-review

Open Access

The incidence and prevalence of Juvenile Idiopathic Arthritis differs between ethnic groups in England

Beesley, R. P., Hyrich, K. L. & Humphreys, J. H., 7 Dec 2023, In: Rheumatology.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Acceptable risks of treatments to prevent rheumatoid arthritis among first-degree relatives: demographic and psychological predictors of risk tolerance

Simons, G., Janssen, E. M., Veldwijk, J., DiSantostefano, R. L., Englbrecht, M., Radawski, C., Valor-Méndez, L., Humphreys, J. H., Bruce, I. N., Hauber, B., Raza, K. & Falahee, M., 13 Dec 2022, In: RMD Open.

Research output: Contribution to journal › Article › peer-review

Does body mass index mediate the relationship between socioeconomic position and incident osteoarthritis?

Witkam, R., Gwinnutt, J., Selby, D., Cooper, R., Humphreys, J. & Verstappen, S., 1 Oct 2022, In: Seminars in arthritis and rheumatism. 56, 152063.

Research output: Contribution to journal › Article › peer-review

Open Access

Incidence and prevalence of Juvenile Idiopathic Arthritis in the United Kingdom 2000-2018: results from the Clinical Practice Research Datalink

Costello, R., McDonagh, J., Hyrich, K. L. & Humphreys, J. H., 1 Jun 2022, In: Rheumatology. 61, 6, p. 2548-2554 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Is the relationship between deprivation and outcomes in rheumatoid arthritis mediated by body mass index? A longitudinal cohort study

Witkam, R., Gwinnutt, J., Humphreys, J., RAMS Co-Investigators & Verstappen, S., 28 Nov 2022, (E-pub ahead of print) In: Rheumatology.

Research output: Contribution to journal › Article › peer-review

Open Access

The association between lower socioeconomic position and functional limitations is partially mediated by obesity in older adults with symptomatic knee osteoarthritis: Findings from the English Longitudinal Study of Ageing

Witkam, R., Verstappen, S. M. M., Gwinnutt, J. M., Cook, M. J., O'Neill, T. W., Cooper, R. & Humphreys, J., 19 Dec 2022, In: Frontiers in Public Health. 10, p. 1053304

Research output: Contribution to journal › Article › peer-review

The Influence of Chronic Pain on Social Care Service Use in the UK

Humphreys, J., Cook, L., Clarkson, P. & Dixon, W., 16 Feb 2022, In: Journal of Long Term Care. p. 40-48

Research output: Contribution to journal › Article › peer-review

Open Access

Validation Studies of Rheumatoid Arthritis Patient-Reported Outcome Measures in Populations at Risk for Inequity: A Systematic Review and Analysis Using the OMERACT Summary of Measurement Properties Equity Table

Barnabe, C., Wattiaux, A., Petkovic, J., Beaton, D., Shea, B., Greer-Smith, R., Humphreys, J., Bartels, C., Tugwell, P. & Umaefulam, V., 1 Aug 2022, In: Seminars in arthritis and rheumatism. 55, 152029.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Correction to: The effect of glucocorticoid therapy on mortality in patients with rheumatoid arthritis and concomitant type II diabetes: a retrospective cohort study

Costello, R. E., Marsden, A., Movahedi, M., Lunt, M., Humphreys, J. H., Emsley, R. & Dixon, W. G., 2 Mar 2021, In: BMC Rheumatology. 5, 1, p. 1-2 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Development of an extension of the OMERACT Summary of Measurement Properties table to capture equity considerations: SOMP-Equity.

Humphreys, J., 27 Sept 2021, In: Seminars in arthritis and rheumatism. 51, 6, p. 1300-1310 11 p.

Research output: Contribution to journal › Article › peer-review

Do associations between education and obesity vary depending on the measure of obesity used? A systematic literature review and meta-analysis

Witkam, R., Gwinnutt, J., Humphreys, J., Gandrup, J., Cooper, R. & Verstappen, S. (Corresponding), 2021, In: SSM - Population Health .

Research output: Contribution to journal › Article › peer-review

Symptoms in first degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the PRe-clinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort.

Costello, R., Humphreys, J., Sergeant, J., Haris, M., Stirling, F., Raza, K., Van Schaardenburg, D. & Bruce, I. N., 2021, In: Arthritis Research and Therapy.

Research output: Contribution to journal › Article › peer-review

2020

The effect of glucocorticoid therapy on mortality in patients with rheumatoid arthritis and concomitant type II diabetes: a retrospective cohort study

Costello, R., Marsden, A., Movahedi, M., Lunt, M., Humphreys, J., Emsley, R. & Dixon, W., 19 Feb 2020, In: BMC Rheumatology. 4, 1, p. 4 4.

Research output: Contribution to journal › Article › peer-review

Open Access

The impact of lifestyle behaviours, physical activity and smoking on morbidity and mortality in patients with rheumatoid arthritis

Gwinnutt, J., Verstappen, S. & Humphreys, J., 2020, In: Best Practice and Research: Clinical Rheumatology. 34, 2, 101562.

Research output: Contribution to journal › Article › peer-review

2019

The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis.

Humphreys, J., 1 Feb 2019, In: Rheumatology (Oxford). 58, 2, p. e3-e42 40 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Early-life predictors of future multi-morbidity: results from the Hertfordshire Cohort

Humphreys, J., Jameson, K., Cooper, C. & Dennison, E., 1 May 2018, In: Age and Ageing. 47, 3, p. 474-478 5 p.

Research output: Contribution to journal › Article › peer-review

Response to: Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis by Kremer and Weinblatt

Humphreys, J., Costello, R., Verstappen, S. M. & Dixon, W. G., Jan 2018, In: Annals of the rheumatic diseases. 77, 1

Research output: Contribution to journal › Article

2017

Patient perceptions of glucocorticoid side effects: a cross-sectional survey of users in an online health community

Costello, R., Patel, R., Humphreys, J., Mcbeth, J. & Dixon, W., 1 Apr 2017, In: BMJ Open. 7, 4, e014603.

Research output: Contribution to journal › Article › peer-review

Open Access

Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate

Humphreys, J. H., Warner, A., Costello, R., Lunt, M., Verstappen, S. & Dixon, W., 2017, In: Annals of the rheumatic diseases.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Anti-carbamylated protein antibodies are associated with long term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register (NOAR)

Humphreys, J., Verheul, M., Barton, A., MacGregor, A., Lunt, M., Toes, R., Symmons, D., Trouw, L. & Verstappen, S., 10 May 2016, In: Annals of the rheumatic diseases. 75, 6, p. 1139-1144

Research output: Contribution to journal › Article › peer-review

Open Access

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.

Ajeganova, S., Humphreys, J. H., Verheul, M. K., van Steenbergen, H. W., van Nies, J. A. B., Hafström, I., Svensson, B., Huizinga, T. W. J., Trouw, L. A., Verstappen, S. M. M. & van der Helm-van Mil, A. H. M., 2016, In: Annals of the rheumatic diseases. 75, 11, p. 1924-1932

Research output: Contribution to journal › Article › peer-review

Response to: 'Evaluation of the association between anticarbamylated protein antibodies and longitudinal course of functional ability in rheumatoid arthritis' by Ajeganova et al

Humphreys, J., Symmons, D. P. M. & Verstappen, S. M. M., Apr 2016, In: Annals of the rheumatic diseases. 75, 4, p. e15

Research output: Contribution to journal › Article

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study

van Wesemael, T. J., Ajeganova, S., Humphreys, J., Terao, C., Muhammad, A., Symmons, D. P. M., MacGregor, A. J., Hafström, I., Trouw, L. A., van der Helm-van Mil, A. H. M., Huizinga, T. W. J., Mimori, T., Toes, R. E. M., Matsuda, F., Svensson, B., Verstappen, S. M. M. & van der Woude, D., 1 Dec 2016, In: Arthritis Research & Therapy. 18, 1, p. 285

Research output: Contribution to journal › Article › peer-review

Open Access

What is the impact of biologic therapies on common co-morbidities in patients with rheumatoid arthritis?

Humphreys, J., Hyrich, K. & Symmons, D., 2016, In: Arthritis Research and Therapy. 18, 282

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register

Ibrahim, I., Humphreys, J., Mokhtar, I., Marshall, T., Verstappen, S., Symmons, D., Viatte, S., Barton, A. & Plant, D., 2015, In: Annals of the rheumatic diseases. 74, 11, p. 2099-2102 3 p.

Research output: Contribution to journal › Article › peer-review

2014

How do we classify rheumatoid arthritis in established disease - can we apply the 2010 American College of Rheumatology / European League Against Rheumatism classification criteria?

Humphreys, J. H., Verstappen, S. M., Scire, C. A., Uhlig, T., Fautrel, B., Sokka, T. & Symmons, D. P., 2014, In: Journal of Rheumatology. 41, 12, p. 2347-2351 4 p.

Research output: Contribution to journal › Article › peer-review

Mortality trends in patients with early rheumatoid arthritis over 20 years: Results from the Norfolk Arthritis Register

Humphreys, J. H., Warner, A., Chipping, J., Marshall, T., Lunt, M., Symmons, D. P. M. & Verstappen, S. M. M., 4 Feb 2014, In: Arthritis Care & Research. 66, 9, p. 1296-1301 5 p.

Research output: Contribution to journal › Article › peer-review

Rheumatoid factor and anti-citrullinated protein antibody positivity, but not level, are associated with increased mortality in patients with rheumatoid arthritis: results from two large independent cohorts.

Humphreys, J. H., van Nies, J., Chipping, J., Marshall, T., Mil, A., Symmons, D. & Verstappen, S., 4 Dec 2014, In: Arthritis Research & Therapy (Online). 16, 6, 483.

Research output: Contribution to journal › Article › peer-review

2013

2010 ACR/EULAR classification criteria for rheumatoid arthritis predict increased mortality in patients with early arthritis: Results from the Norfolk Arthritis Register

Humphreys, J. H., Verstappen, S. M. M., Hyrich, K. L., Chipping, J. & Symmons, D. P. M., Jun 2013, In: Rheumatology. 52, 6, p. 1141-1142 2 p.

Research output: Contribution to journal › Article › peer-review

Association of morbid obesity with disability in early inflammatory polyarthritis: Results from the Norfolk Arthritis Register

Humphreys, J. H., Verstappen, S. M. M., Mirjafari, H., Bunn, D., Lunt, M., Bruce, I. N. & Symmons, D. P. M., Jan 2013, In: Arthritis Care & Research. 65, 1, p. 122-126 4 p.

Research output: Contribution to journal › Article › peer-review

Étude et suivi: Rheumatoid arthritis in the 21st century

Humphreys, J. H. & Verstappen, S. M. M., Oct 2013, In: Journal of Rheumatology. 40, 10, p. 1637-1639 2 p.

Research output: Contribution to journal › Article › peer-review

Postpublication validation of the 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Where do we stand?

Humphreys, J. H. & Symmons, D. P. M., Mar 2013, In: Current Opinion in Rheumatology. 25, 2, p. 157-163 6 p.

Research output: Contribution to journal › Article › peer-review

The incidence of rheumatoid arthritis in the UK: Comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register

Humphreys, J. H., Verstappen, S. M. M., Hyrich, K. L., Chipping, J. R., Marshall, T. & Symmons, D. P. M., Aug 2013, In: Annals of the rheumatic diseases. 72, 8, p. 1315-1320 5 p.

Research output: Contribution to journal › Article › peer-review

Jenny H Humphreys, MRCP, PhD

Research output

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