John Robert Davis

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Overview

JR joined the University of Manchester in October 2022 where he has been establishing the Hungry Tissue lab on a Wellcome ISSF and a Dean's prize fellowship. The Hungry Tissue lab is interested in understanding how metabolism and nutrients impact how tissues generate their shape during morphogenesis. To examine this question the Hungry Tissue lab employ biofabrication techniques to mimic 2D and 3D morphogenesis as well as Drosophila embryogenesis as model systems.

JR started his training with a PhD in the lab of Brian Stramer at King's College London examining how contact inhibition of locomotion, a process where migrating cells repel each other, drives Drosophila embryonic patterns, and was awarded the BSDB Beddington medal and YEN Sammy Lee memorial medal for this work. JR joined the lab of Nic Tapon at the Francis Crick Institute for his post-doc partly funded with a Sir Henry Wellcome fellowship. Initially, continuing research in Drosophila morphogenesis, JR found that ECM remodelling acts as a developmental timing mechanism to coordinate growth and was awarded the Francis Crick Science Achievement Award. At the end of his post-doc he examined how mammalian tissues balance forces between the substrate and cell-cell junctions. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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