John Helliwell

Begum, S., Cianci, M., Durbeej, B., Falklöf, O., Haedener, A., Helliwell, J., Helliwell, M., Regan, A. & Watt, C. I., 13 Mar 2015, In: Physical Chemistry Chemical Physics. 17, p. 16723-16732 9 p.

Research output: Contribution to journal › Article › peer-review

2014

Carboplatin binding to histidine

Tanley, S. W., Diederichs, K., Kroon-Batenburg, L. M., Levy, C., Schreurs, A. M. & Helliwell, J. R., 2014, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 70, 9, p. 1135-1142 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Chemical conversion of cisplatin and carboplatin with histidine in a model protein crystallized under sodium iodide conditions

Tanley, S. W. M. & Helliwell, J. R., 29 Aug 2014, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 70, 9, p. 1127-1131 5 p.

Research output: Contribution to journal › Article › peer-review

The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6octahedral complex to a PtI3moiety bound to His15

Tanley, S. W. M., Starkey, L. V., Lamplough, L., Kaenket, S. & Helliwell, J. R., 29 Aug 2014, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 70, 9, p. 1132-1134 2 p.

Research output: Contribution to journal › Article › peer-review

The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15

Tanley, S. W. M., Starkey, L.-V., Lamplough, L., Kaenket, S. & Helliwell, J. R., 2014, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications.

Research output: Contribution to journal › Article › peer-review

2013

Experiences with archived raw diffraction images data: Capturing cisplatin after chemical conversion of carboplatin in high salt conditions for a protein crystal

Tanley, S. W. M., Diederichs, K., Kroon-Batenburg, L. M. J., Schreurs, A. M. M. & Helliwell, J. R., Nov 2013, In: Journal of Synchrotron Radiation. 20, 6, p. 880-883 3 p.

Research output: Contribution to journal › Article › peer-review

Experience with exchange and archiving of raw data: Comparison of data from two diffractometers and four software packages on a series of lysozyme crystals

Tanley, S. W. M., Schreurs, A. M. M., Helliwell, J. R. & Kroon-Batenburg, L. M. J., Feb 2013, In: Journal of Applied Crystallography. 46, 1, p. 108-119 11 p.

Research output: Contribution to journal › Article › peer-review

The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation

Helliwell, J. R. & Tanley, S. W. M., Jan 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 1, p. 121-125 4 p.

Research output: Contribution to journal › Article › peer-review

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2012

Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure

Tanley, S. W. M., Schreurs, A. M. M., Kroon-Batenburg, L. M. J. & Helliwell, J. R., Nov 2012, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68, 11, p. 1300-1306 6 p.

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Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein

Tanley, S. W. M., Schreurs, A. M. M., Kroon-Batenburg, L. M. J., Meredith, J., Prendergast, R., Walsh, D., Bryant, P., Levy, C. & Helliwell, J. R., May 2012, In: Acta Crystallographica Section D: Biological Crystallography. 68, 5, p. 601-612 11 p.

Research output: Contribution to journal › Article › peer-review

The evolution of synchrotron radiation and the growth of its importance in crystallography

Helliwell, J. R., 1 Jan 2012, In: Crystallography Reviews. 18, 1, p. 33-93

Research output: Contribution to journal › Article › peer-review

2011

Deriving the ultrastructure of α-crustacyanin using lower-resolution structural and biophysical methods

Rhys, N. H., Wang, M. C., Jowitt, T. A., Helliwell, J. R., Grossmann, J. G. & Baldock, C., Jan 2011, In: Journal of Synchrotron Radiation. 18, 1, p. 79-83 4 p.

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Open Access

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2010

Crystallographic analysis of counterion effects on subtilisin enzymatic action in acetonitrile

Cianci, M., Tomaszewski, B., Helliwell, J. R. & Halling, P. J., 3 Mar 2010, In: Journal of the American Chemical Society. 132, 7, p. 2293-2300 7 p.

Research output: Contribution to journal › Article › peer-review

Determination of zinc incorporation in the Zn-substituted gallophosphate ZnULM-5 by multiple wavelength anomalous dispersion techniques

Helliwell, M., Helliwell, J. R., Kaucic, V., Zabukovec Logar, N., Teat, S. J., Warren, J. E. & Dodson, E. J., 2010, In: Acta Crystallographica Section B: Structural Science. 66, 3, p. 345-357 12 p.

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Open Access

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The structural chemistry and structural biology of colouration in marine crustacea

Helliwell, J. R., Jul 2010, In: Crystallography Reviews. 16, 3, p. 231-242 11 p.

Research output: Contribution to journal › Article › peer-review

Time-dependent analysis of K2PtBr6 binding to lysozyme studied by protein powder and single crystal X-ray analysis

Helliwell, J. R., Tony Bell, A. M., Bryant, P., Fisher, S. J., Habash, G., Helliwell, M., Margiolaki, I., Kaenket, S., Watier, Y., Wright, J. & Yalamanchilli, S., 2010, In: Zeitschrift fur Kristallographie. 225, 12, p. 570-575 5 p.

Research output: Contribution to journal › Article › peer-review

Why do lobsters change colour on cooking? or Cracking lobster shell protein structures and explaining the colour shift

Helliwell, J. R., 2010, In: Manchester Memoirs. 147, p. 53-65

Research output: Contribution to journal › Article

X-ray crystal structure and time-resolved spectroscopy of the blue carotenoid violerythrin

Polívka, T., Frank, H. A., Enriquez, M. M., Niedzwiedzki, D. M., Liaaen-Jensen, S., Hemming, J., Helliwell, J. R. & Helliwell, M., 8 Jul 2010, In: Journal of Physical Chemistry B. 114, 26, p. 8760-8769 9 p.

Research output: Contribution to journal › Article › peer-review

2009

An evaluation review of the prediction of protonation states in proteins versus crystallographic experiment

Fisher, S. J., Wilkinson, J., Henchman, R. H. & Helliwell, J. R., Oct 2009, In: Crystallography Reviews. 15, 4, p. 231-259 28 p.

Research output: Contribution to journal › Article › peer-review

X-ray crystal structures of diacetates of 6-s-cis and 6-s-trans astaxanthin and of 7,8-didehydroastaxanthin and 7,8,7′,8′- tetradehydroastaxanthin: Comparison with free and protein-bound asta-xanthins

Bartalucci, G., Fisher, S., Helliwell, J. R., Helliwell, M., Liaaen-Jensen, S., Warren, J. E. & Wilkinson, J., 2009, In: Acta Crystallographica Section B: Structural Science. 65, 2, p. 238-247 9 p.

Research output: Contribution to journal › Article › peer-review

2008

An investigation into structural changes due to deuteration

Fisher, S. J. & Helliwell, J. R., 18 Apr 2008, In: Acta Crystallographica Section A: Foundations of Crystallography. 64, 3, p. 359-367 8 p.

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An investigation into the protonation states of the C1 domain of cardiac myosin-binding protein C

Fisher, S. J., Helliwell, J. R., Khurshid, S., Govada, L., Redwood, C., Squire, J. M. & Chayen, N. E., 14 May 2008, In: Acta Crystallographica Section D: Biological Crystallography. 64, 6, p. 658-664 6 p.

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Open Access

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Macromolecular crystal twinning, lattice disorders and multiple crystals

Helliwell, J. R., Jul 2008, In: Crystallography Reviews. 14, 3, p. 189-250 61 p.

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Open Access

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Science experiments via telepresence at a synchrotron radiation source facility

Warren, J. E., Diakun, G., Bushnell-Wye, G., Fisher, S., Thalal, A., Helliwell, M. & Helliwell, J. R., 19 Feb 2008, In: Journal of Synchrotron Radiation. 15, 2, p. 191-194 3 p.

Research output: Contribution to journal › Article › peer-review

Structure characterisation of nanoporous materials using state-of-the-art single-crystal X-ray and neutron diffraction techniques

Helliwell, M., Helliwell, J. R., Logar, N. Z., Mali, G., Tušar, N. N. & Kaučič, V., 2008, In: Acta Chimica Slovenica. 55, 4, p. 709-718 9 p.

Research output: Contribution to journal › Article › peer-review

The interdependence of wavelength, redundancy and dose in sulfur SAD experiments

Cianci, M., Helliwell, J. R. & Suzuki, A., 18 Nov 2008, In: Acta Crystallographica Section D: Biological Crystallography. 64, 12, p. 1196-1209 13 p.

Research output: Contribution to journal › Article › peer-review

2007

The determination of protonation states in proteins

Ahmed, H. U., Blakeley, M. P., Cianci, M., Cruickshank, D. W. J., Hubbard, J. A. & Helliwell, J. R., 17 Jul 2007, In: Acta Crystallographica Section D: Biological Crystallography. 63, 8, p. 906-922 16 p.

Research output: Contribution to journal › Article › peer-review

Unravelling the chemical basis of the bathochromic shift in the lobster carapace; new crystal structures of unbound astaxanthin, canthaxanthin and zeaxanthin

Bartalucci, G., Coppin, J., Fisher, S., Hall, G., Helliwell, J. R., Helliwell, M. & Liaaen-Jensen, S., 16 Mar 2007, In: Acta Crystallographica Section B: Structural Science. 63, 2, p. 328-337 9 p.

Research output: Contribution to journal › Article › peer-review

2006

Crystal structure of peach Pru p 3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens

Pasquato, N., Berni, R., Folli, C., Folloni, S., Cianci, M., Pantano, S., Helliwell, J. R. & Zanotti, G., 24 Feb 2006, In: Journal of molecular biology. 356, 3, p. 684-694 10 p.

Research output: Contribution to journal › Article › peer-review

Protein Crystallography and Synchrotron radiation; current status and future landscape

Maclean, E. J., Rizkallah, P. J. & Helliwell, J. R., 2006, In: European Pharmaceutical Review. p. 71-76 6 p.

Research output: Contribution to journal › Article › peer-review

2005

Ab initio structure determination using dispersive differences from multiple-wavelength synchrotron-radiation powder diffraction data

Helliwell, J. R., Helliwell, M. & Jones, R. H., Nov 2005, In: Acta Crystallographica Section A: Foundations of Crystallography. 61, 6, p. 568-574 6 p.

Research output: Contribution to journal › Article › peer-review

A high-throughput structural biology/proteomics beamline at the SRS on a new multipole wiggler

Cianci, M., Antonyuk, S., Bliss, N., Bailey, M. W., Buffey, S. G., Cheung, K. C., Clarke, J. A., Derbyshire, G. E., Ellis, M. J., Enderby, M. J., Grant, A. F., Holbourn, M. P., Laundy, D., Nave, C., Ryder, R., Stephenson, P., Helliwell, J. R. & Hasnain, S. S., Jul 2005, In: Journal of Synchrotron Radiation. 12, 4, p. 455-466 11 p.

Research output: Contribution to journal › Article › peer-review

2004

The 15-K neutron structure of saccharide-free concanavalin A

Blakeley, M. P., Kalb, A. J., Helliwell, J. R. & Myles, D. A. A., 23 Nov 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 47, p. 16405-16410 5 p.

Research output: Contribution to journal › Article › peer-review

2003

S-SWAT (softer single-wavelength anomalous technique): Potential in high-throughput protein crystallography

Olczak, A., Cianci, M., Hao, Q., Rizkallah, P. J., Raftery, J. & Helliwell, J. R., Jul 2003, In: Acta Crystallographica Section A: Foundations of Crystallography. 59, 4, p. 327-334 7 p.

Research output: Contribution to journal › Article › peer-review

2002

2001

The combination of molecular dynamics with crystallography for elucidating protein-ligand interactions: A case study involving peanut lectin complexes with T-antigen and lactose

Pratap, J. V., Bradbrook, G. M., Reddy, G. B., Surolia, A., Raftery, J., Helliwell, J. R. & Vijayan, M., 2001, In: Acta Crystallographica Section D: Biological Crystallography. 57, 11, p. 1584-1594 10 p.

Research output: Contribution to journal › Article › peer-review

John Helliwell, DSc

Research output

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