John Gardiner, B.Sc., Ph.D., F.R.S.C.

BSc (Durham). Harrison-Shearer Prize for Chemistry (highest First) and University Pemberton Scholarship (Highest Finals Part 1, University)

PhD (Durham). Total synthesis of alkaloids in Prof Martin Bryce's lab.

Postdoctoral research: University of California at Los Angeles (UCLA) 1988-90 with Mike Jung, returing as Visiting Research Fellow @ UCLA, 1991 and 1992.

Lecturer in Medicinal Chemistry : Aston University 1990-93

Moved to UMIST Chemistry in January 1994, and then to the University of Manchester.

Around 16 postdoctoral researchers, ~50 graduate students and 30+ visitors/interns have worked in our group.

Publication output of over 120 papers, review and book chapters.

Carbohydrates and Oligosaccharides: We have active interests in developing new methods to provide biologically-relevant oligosaccharides, with a focus on tools to probe chemical biology and for biomedical targets. Particularly significant interests are in the synthetic heparin oligosaccharide area where we have recently reported a large jump in synthetic scalability for long heparins, a new accelerated block synthesis and have also developed the longest synthetic heparin-like sequences yet reported.

Biocatalysis: Collaboration with Prof Nigel Scruttons lab discovering, developing, engineering and applying new enzyme catalysis for high value chemical synthesis, using screening, engineering and synthetic biology.

Heterocycles: Oligo-heterocyclic synthesis and biological activities (eg DNA ligands).

Dendrimers, polyaryls and nanographene: New arhcitectures based on polaryles and their applications nanographenes.

• Biocatalysis
• Biotechnology
• Chemical Biology
• Drug discovery
• Material Synthesis
• Nanomaterials
• Organic materials and polymers
• Organic Synthesis
• Synthesis
• Synthetic Biology
• Chemical Biology
• Health and Chemical Intervention