Research output per year
Research output per year
Personal profile
Memberships of committees and professional bodies
- Member of the Physiological Society, 2006 till present
- Member of the American Society for Cell Biology, 2007 till present
- Member of the International Society of Heart Research, 2007 till present
- Affiliate Member of the Society for Experimental Biology, 2007
Methodological knowledge
Molecular biology: preparation of total RNAand micro RNA isolation and measurements of its effect and cDNA from different regions of rat heart (atrium, ventricle and sinoatrial node), primer design, quantitative PCR and DNA and RNA gel electrophoresis.
- Extensive experience in Laser capture microdissection and RNA isolation from the microdissected tissues
- Extensive experience in histology, immunocytochemistry and confocal microscopy of tissues.
- Extensive experience in calcium imaging in the cardiac myocytes
- Extracellular potential mapping of the sinoatrial node.
- Intracellular action potential recording from the sinoatrial node.
- Isolation of sinoatrial node, atrioventricular conduction axis and Purkinje fibres from different species: mouse, rat, rabbit and guinea-pig.
- Some experience in In situ hybridization (ISH).
Qualifications
Level 5 Award in Management
certified by the Institute of Leadership and Management (2010)
Ph.D. in Cardiovascular Medicine
Faculty of Medical and Human Sciences, University of Manchester, UK (2008)
Thesis title: “Age-dependent remodelling of the sinoatrial node and right atrium.”
M.Sc. in Physiology
Faculty of Medicine, Menoufyia University, Egypt (1998 – 2003), grade (very good).
Thesis title: “Effect of vanadate administration on renal functions and some metabolic aspects in diabetic rats.”
MBChB
Faculty of Medicine, Menoufyia University, Egypt (1989 – 1996), grade (very good).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease
Boyett, M., Yanni Gerges, J., Tellez, J. O., Bucchi, A., Mesirca, P., Cai, X., Logantha, S. J. R. J., Wilson, C., Anderson, C., Ariyaratnam, J., Stuart, L., Nakao, S., Allah, E. A., Jones, S. A., Lancaster, M., Stephenson, R. S., Chandler, N., Smith, M., Bussey, C. & Monfredi, O. & 6 others, , 2 Nov 2021, In: Progress in biophysics and molecular biology. 166, p. 61-85 25 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Remodelling of the Purkinje network in congestive heart failure in the rabbit
Logantha, S., Cai, X., Yanni Gerges, J., Jones, C. B., Stephenson, R. S., Stuart, L., Quigley, G., Monfredi, O., Nakao, S., Oh, I.-Y., Starborg, T., Kitmitto, A., Vohra, A., Hutcheon, R. C., Corno, A. F., Jarvis, J. C., Dobrzynski, H., Boyett, M. & Hart, G., 4 May 2021, (Accepted/In press) In: Circulation: Heart Failure.Research output: Contribution to journal › Article › peer-review
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Silencing miR-370-3p rescues funny current and sinus node function in heart failure
Yanni Gerges, J., D'Souza, A., Wang, Y., Li, N., Hansen, B. J., Zakharkin, S., Smith, M., Hayward, C., Whitson, B. A., Mohler, P. J., Janssen, P. M. L., Zeef, L., Choudhury, M., Zi, M., Cai, X., Logantha, S., Nakao, S., Atkinson, A., Petkova, M. & Doris, U. & 8 others, , 9 Jul 2020, In: Scientific Reports. 10, 11279.Research output: Contribution to journal › Article › peer-review
Open Access -
Electrical conduction system remodelling in streptozotocin-induced diabetes mellitus rat heart
Zhang, Y., Wang, Y., Yanni Gerges, J., Quereshi, M. A., Logantha, S., Al Adhamn, S., Boyett, M., Gardiner, N., Sun, H., Howarth, F. C. & Dobrzynski, H., 2019, In: Frontiers in Physiology. 10, p. 1 15 p., 826.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels
Saeed, Y., Temple, I. P., Borbas, Z., Atkinson, A., Yanni Gerges, J., Maczewski, M., Mackiewicz, U., Aly, M., Logantha, S., Garratt, C. & Dobrzynski, H., 2018, In: Heart Rhythm.Research output: Contribution to journal › Article › peer-review
Open Access