Josephine Naish

2025

Comprehensive reference ranges for cardiovascular magnetic resonance: time to move on from single centre data?

Farrant, J. P., Black, N., Yamagata, K., Soltani, F., Orsborne, C., Yan, C. K., Clark, D., Pleva, L., Garratt, C., Schmitt, M., Clarke, B., Naish, J., Reid, A. & Miller, C. A., 27 Mar 2025, In: The International Journal of Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Remote myocardial fibrosis predicts adverse outcome in patients with myocardial infarction on clinical cardiac magnetic resonance imaging

Black, N., Bradley, J., Schelbert, E. B., Bonnett, L. J., Lewis, G., Lagan, J., Orsborne, C., Brown, P., Soltani, F., Fröjdh, F., Ugander, M., Wong, T. C., Fukui, M., Cavalcante, J. L., Naish, J., Williams, S., McDonagh, T., Schmitt, M. & Miller, C., 23 Jul 2024, In: Journal of Cardiovascular Magnetic Resonance. 101064.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Disease specific therapy for the treatment of the cardiovascular manifestations of Fabry disease: A systematic review

Orsborne, C., Black, N., Naish, J., Woolfson, P., Reid, A., Schmitt, M., Jovanovic, A. & Miller, C., 15 Dec 2023, In: Heart. 110, 15

Research output: Contribution to journal › Article › peer-review

Open Access

GDF-15 in patients with or at risk of heart failure but before first hospitalisation

Bradley, J., Schelbert, E. B., Bonnett, L. J., Lewis, G. A., Lagan, J., Orsborne, C., Brown, P. F., Black, N., Naish, J. H., Williams, S., McDonagh, T., Schmitt, M. & Miller, C. A., 13 Jul 2023, (Accepted/In press) In: Heart.

Research output: Contribution to journal › Article › peer-review

Inflammatory Fabry Cardiomyopathy Demonstrated Using Simultaneous [¹⁸F]-FDG PET-CMR

Orsborne, C., Anton-Rodrigez, J. M., Sherratt, N., Watkins, A., Lohezic, M., Clark, D., Lloyd, W., Naish, J. H., Woolfson, P., Reid, A. B., Schmitt, M., Muthu, S., Arumugam, P., Jovanovic, A. & Miller, C. A., 7 Jun 2023, In: JACC: Case Reports. 15, 101863.

Research output: Contribution to journal › Article › peer-review

Open Access

Inflammatory Fabry cardiomyopathy demonstrated using simultaneous hybridised 18F-fluorodeoxyglucose positron emission tomography, cardiovascular magnetic resonance imaging

Orsborne, C., Anton-Rodrigez, J. M., Sherratt, N., Watkins, A., Lohezic, M., Clark, D., Lloyd, W., Naish, J., Woolfson, P., Reid, A., Schmitt, M., Muthu, S., Arumugam, P., Jovanovic, A. & Miller, C., 7 Apr 2023, (Accepted/In press) In: JACC: Case Reports.

Research output: Contribution to journal › Article › peer-review

Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy

Farrant, J., Dodd, S., Vaughan, C., Reid, A., Schmitt, M., Garratt, C., Akhtar, M., Mahmod, M., Neubauer, S., Cooper, R., Prasad, S. K., Singh, A., Valkovič, L., Raman, B., Ashkir, Z., Clayton, D., Baroja, O., Duran, B., Spowart, C. & Bedson, E. & 4 others, Naish, J., Harrington, C. F., Miller, C. & TEMPEST investigators, 12 Jul 2023, In: Heart. 109, 15, p. 1175-1182

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Acute and chronic cardiopulmonary effects of high dose interleukin-2 therapy: an observational magnetic resonance imaging study

Lagan, J., Naish, J. H., Campbell, C., Chow, S., Pillai, M., Bradley, J., Francis , L., Clark, D., Macnab, A., Dobson, R., Schelbert, E. B., Schmitt, M., Hawkins, R. & Miller, C. A., 24 May 2022, (Accepted/In press) In: Diagnostics.

Research output: Contribution to journal › Article › peer-review

The Diagnostic and Prognostic Utility of Contemporary Cardiac Magnetic Resonance in Suspected Acute Myocarditis

Lagan, J., Fortune, C., Hutchings, D., Bradley, J., Naish, J. H., Timoney, R., Prescott, D., Bain, H. D. C., Bangi, T., Mcintosh, J., Egdell, R., Irwin, R. B., Clark, D., Schelbert, E. B., Nucifora, G., Schmitt, M. & Miller, C. A., 10 Jan 2022, In: Diagnostics. 12, 1, p. 156

Research output: Contribution to journal › Article › peer-review

Open Access

Validated Model for Prediction of Adverse Cardiac Outcome in Patients with Fabry Disease

Orsborne, C., Bradley, J., Bonnett, L. J., Pleva, L. A., Naish, J., Clark, D. G., Abidin, N., Woolfson, P., Nucifora, G., Schmitt, M., Jovanovic, A., Miller, C. & Reid, A., 14 Jun 2022, (Accepted/In press) In: Journal of the American College of Cardiology.

Research output: Contribution to journal › Article › peer-review

2021

Cardiac involvement in cystic fibrosis evaluated using cardiopulmonary magnetic resonance

Lagan, J., Naish, J. H., Bradley, J., Fortune, C., Palmer, C., Clark, D., Schelbert, E. B., Schmitt, M., Bright-Thomas, R. & Miller, C., 11 Dec 2021, (Accepted/In press) In: The International Journal of Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Mechanisms underlying the association of chronic obstructive pulmonary disease with heart failure

Lagan, J., Schelbert, E. B., Naish, J., Vestbo, J., Fortune, C., Bradley, J., Belcher, J., Hearne, E., Ogunyemi, F., Timoney, R., Prescott, D., Bain, H. D., Bangi, T., Zaman, M., Wong, C., Ashworth, A., Thorpe, H., Egdell, R., McIntosh , J. & Irwin, B. & 6 others, Clark, D., Devereux, G., Quint, J. K., Barraclough, R., Schmitt, M. & Miller, C., 19 Mar 2021, (Accepted/In press) In: JACC: Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Substrate for the Myocardial Inflammation-Heart Failure Hypothesis Identified Using Novel USPIO Methodology

Lagan, J., Naish, J., Simpson, K., Zi, M., Cartwright, E., Foden, P., Morris, J., Clark, D., Birchall, L., Caldwell, J., Trafford, A., Fortune, C., Cullen, M. H., Chaudhuri, N., Fildes, J., Sarma, J., Schelbert, E. B., Schmitt, M., Piper Hanley, K. & Miller, C., 1 Feb 2021, In: JACC: Cardiovascular Imaging. 14, 2, p. 365-376 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Blood-brain barrier leakage is increased in Parkinson’s disease

Al-Bachari, S., Naish, J. H., Parker, G. J. M., Emsley, H. C. A. & Parkes, L. M., 22 Dec 2020, In: Frontiers in Physiology. 11, p. 1-12 12 p., 593026.

Research output: Contribution to journal › Article › peer-review

Open Access

Diffusion model comparison identifies distinct tumor sub-regions and tracks treatment response

McHugh, D. J., Lipowska-Bhalla, G., Babur, M., Watson, Y., Peset, I., Mistry, H. B., Hubbard Cristinacce, P. L., Naish, J. H., Honeychurch, J., Williams, K. J., O'Connor, J. P. B. & Parker, G. J. M., 2020, In: Magnetic Resonance in Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

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Myocardial involvement in eosinophilic granulomatosis with polyangiitis evaluated with cardiopulmonary magnetic resonance

Lagan, J., Naish, J., Fortune, C., Bradley, J., Clark, D., Niven, R., Chaudhuri, N., Schelbert, E. B., Schmitt, M. & Miller, C., 19 Nov 2020, (E-pub ahead of print) In: The International Journal of Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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Numerical Study of Atrial Fibrillation Effects on Flow Distribution in Aortic Circulation

Deyranlou, A., Naish, J., Miller, C., Revell, A. & Keshmiri, A., Apr 2020, In: Annals of Biomedical Engineering. 48, 4, p. 1291-1308 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

A prospective study of Change in Liver Function and Fat in patients with colorectal liver metastases undergoing pre-operative chemotherapy: protocol for the CLiFF study

Parmar, K., O'Reilly, D., Valle, J., Braun, M., Naish, J., Williams, S. R., Lloyd, W., Malcomson, L., Cresswell, K., Bamford, C. & Renehan, A., 23 Oct 2019, (Accepted/In press) In: BMJ Open.

Research output: Contribution to journal › Article › peer-review

Considerations for clinical trials targeting the myocardial interstitium

Lewis, G., Dodd, S., Naish, J., Selvanayagam, J., Dweck, M. R. & Miller, C., 14 Aug 2019, In: JACC: Cardiovascular Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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Major Adverse Cardiovascular Events following Simultaneous Pancreas and Kidney Transplantation in the United Kingdom

Yiannoullou, P., Summers, A., Goh, S. C., Fullwood, C., Khambalia, H., Moinuddin, Z., Shapey, I., Naish, J., Miller, C., Augustine, T., Rutter, M. & Van Dellen, D., 2019, In: Diabetes Care..

Research output: Contribution to journal › Article › peer-review

Open Access

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84 Downloads (Pure)

Pirfenidone in Heart Failure With Preserved Ejection Fraction - Rationale and Design of the PIROUETTE Trial

Lewis, G., Schelbert, E. B., Naish, J., Bedson, E., Dodd, S., Eccleson, H., Clayton, D., Duran-Jimenez, B., McDonagh, T., Williams, S. G., Cooper, A., Cunnington, C., Ahmed, F. Z., Viswesvaraiah, R., Russell, S., Neubauer, S., Williamson, P. & Miller, C., 2019, In: Cardiovascular Drugs and Therapy.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

A biomimetic tumour tissue phantom for validating diusion-weighted MRI measurements

Mchugh, D., Zhou, F., Wimpenny, I., Poologasundarampilla, G., Naish, J., Hubbard Cristinacce, P. L. & Parker, G. J., 1 Jul 2018, In: Magnetic Resonance in Medicine. 80, 1, p. 147-158 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI

Abid, K. A., Sobowale, O. A., Parkes, L. M., Naish, J., Parker, G. J. M., du Plessis, D., Brough, D., Barrington, J., Allan, S. M., Hinz, R. & Parry-Jones, A. R., Mar 2018, In: Journal of Neuroimaging. 28, 2, p. 158-161 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology

Little, R., Jamin, Y., Boult, J. K. R., Naish, J., Watson, Y., Cheung, S., Holliday, K., Lu, H., Mchugh, D., Irlam, J., West, C., Betts, G., Ashton, G., Reynolds, A. R., Maddineni, S., Clarke, N. W., Parker, G. J., Waterton, J., Robinson, S. P. & O'Connor, J., 2018, In: Radiology. 288, 3, p. 739-747

Research output: Contribution to journal › Article › peer-review

Open Access

Modelling Gadoxetate Liver Uptake and Efflux Using DCE-MRI Enables Preclinical Quantification of Transporter-Mediated Drug-Drug Interactions

Georgiou, L., Penny, J., Nicholls, G., Woodhouse, N., Blé, F.-X., Naish, J. & Hubbard Cristinacce, P. L., Sept 2018, In: Investigative Radiology. 53, 9

Research output: Contribution to journal › Article › peer-review

Open Access

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277 Downloads (Pure)

The effect of 1.5T cardiac magnetic resonance on human circulating leukocytes

Critchley, W., Reid, A., Morris, J., Naish, J., Stone, J., Ball, A., Major, T., Clark, D., Waldron, N., Fortune, C., Lagan, J., Lewis, G., Ainslie, M., Schelbert, E. B., Davis, D. M., Schmitt, M., Fildes, J. & Miller, C., 21 Jan 2018, In: European Heart Journal. 39, 4, p. 305-312 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Towards a 'resolution limit' for DW-MRI tumour microstructural models. A simulation study investigating the feasibility of distinguishing between microstructural changes.

McHugh, D. J., Hubbard Cristinacce, P. L., Naish, J. H. & Parker, G. J. M., 2018, In: Magnetic Resonance in Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Evaluation of non-contrast MRI biomarkers in lupus nephritis

Skeoch, S., Hubbard Cristinacce, P. L., Dobbs, M., Naish, J., Woodhouse, N., Ho, M., Waterton, J., Parker, G. J. & Bruce, I. N., 2017, In: Clinical and Experimental Rheumatology. p. 954-958

Research output: Contribution to journal › Article › peer-review

Open Access

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MR Imaging Measurements of Altered Placental Oxygenation in Pregnancies Complicated by Fetal Growth Restriction

Ingram, E., Morris, D., Naish, J., Meyers, J. & Johnstone, E., 2017, In: Radiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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Quantitative assessment of liver function using Gadoxetate-Enhanced Magnetic Resonance Imaging: Monitoring Transporter-Mediated processes in healthy volunteers

Georgiou, L., Penny, J., Nicholls, G., Woodhouse, N., Blé, F.-X., Hubbard Cristinacce, P. L. & Naish, J. H., 1 Feb 2017, In: Investigative Radiology. 52, 2, p. 111-119 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

COPD patients have short lung magnetic resonance T1 relaxation time

Alamidi, D. F., Morgan, A. R., Hubbard Cristinacce, P., Nordenmark, L. H., Hockings, P. D., Lagerstrand, K. M., Young, S. S., Naish, J. H., Waterton, J. C., Maguire, N. C., Olsson, L. E. & Parker, G., 2016, In: C O P D. 13, p. 153-159

Research output: Contribution to journal › Article › peer-review

Open Access

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R1 changes in the human placenta at 3 T in response to a maternal oxygen challenge protocol

Ingram, E., Hawkins, L., Morris, D. M., Myers, J., Sibley, C. P., Johnstone, E. D. & Naish, J. H., Mar 2016, In: Placenta. 39, p. 151-3 3 p.

Research output: Contribution to journal › Article › peer-review

T1 Relaxation Time in Lungs of Asymptomatic Smokers

Alamidi, D. F., Kindvall, S. S. I., Cristinacce, P., McGrath, D. M., Young, S. S., Naish, J. H., Waterton, J. C., Wollmer, P., Gonzalez-Diaz, S. N., Olsson, M., Hockings, P. D., Lagerstrand, K. M., Parker, G. J. M. & Olsson, L. E., 9 Mar 2016, In: PLoS ONE. 11, 3, p. e0149760 e0149760.

Research output: Contribution to journal › Article › peer-review

Open Access

T1-weighted Dynamic Contrast-enhanced MR Imaging of the Lung in Asthma: Semiquantitative Analysis for the Assessment of Contrast Agent Kinetic Characteristics.

Zhang, W., Niven, R. M., Young, S. S., Liu, Y.-Z., Parker, G. & Naish, J. H., Mar 2016, In: Radiology. 278, 3, p. 906-916

Research output: Contribution to journal › Article › peer-review

Open Access

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150 Downloads (Pure)

2015

Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma-Initial experience.

Zhang, W., Niven, R., Young, S., Liu, Y., Parker, G. & Naish, J. H., 2015, In: European Journal of Radiology. 84, 2, p. 318-326 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

MR Quantitative Equilibrium Signal Mapping: A Reliable Alternative to CT in the Assessment of Emphysema in Patients with Chronic Obstructive Pulmonary Disease

Zhang, W.-J., Hubbard Cristinacce, P., Bondesson, E., Nordenmark, L. H., Young, S. S., Liu, Y.-Z., Singh, D., Naish, J. H. & Parker, G. J., 2015, In: Radiology. 275, 2, p. 579-588 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

Absence of PO2 change in fetal brain DESPITE Po2 increase in placenta in response to maternal oxygen challenge.

Huen, I., Morris, D. M., Wright, C., Sibley, C. P., Naish, J. H. & Johnstone, E. D., Dec 2014, In: BJOG : an international journal of obstetrics and gynaecology. 121, 13

Research output: Contribution to journal › Article › peer-review

Multiparametric cardiovascular magnetic resonance assessment of cardiac allograft vasculopathy

Miller, C. A., Sarma, J., Naish, J. H., Yonan, N., Williams, S. G., Shaw, S. M., Clark, D., Pearce, K., Stout, M., Potluri, R., Borg, A., Coutts, G., Chowdhary, S., McCann, G. P., Parker, G. J. M., Ray, S. G. & Schmitt, M., 4 Mar 2014, In: Journal of the American College of Cardiology. 63, 8, p. 799-808 9 p.

Research output: Contribution to journal › Article › peer-review

Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: A pilot study

Miller, C. A., Naish, J. H., Shaw, S. M., Yonan, N., Williams, S. G., Clark, D., Bishop, P. W., Ainslie, M. P., Borg, A., Coutts, G., Parker, G. J. M., Ray, S. G. & Schmitt, M., 20 Jul 2014, In: Journal of Cardiovascular Magnetic Resonance. 16, 1, 52.

Research output: Contribution to journal › Article › peer-review

Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT.

Crabb, M. G., Davidson, J. L., Little, R., Wright, P., Morgan, A. R., Miller, C. A., Naish, J. H., Parker, G. J. M., Kikinis, R., McCann, H. & Lionheart, W. R. B., May 2014, In: Physiological Measurement. 35, 5, p. 863-879 16 p.

Research output: Contribution to journal › Article › peer-review

Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma.

Linnik, I. V., Scott, M. L. J., Holliday, K. F., Woodhouse, N., Waterton, J. C., O'Connor, J. P. B., Barjat, H., Liess, C., Ulloa, J., Young, H., Dive, C., Hodgkinson, C. L., Ward, T., Roberts, D., Mills, S. J., Thompson, G., Buonaccorsi, G. A., Cheung, S., Jackson, A. & Naish, J. H. & 1 others, Parker, G. J. M., May 2014, In: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 71, 5, p. 1854-1862 8 p.

Research output: Contribution to journal › Article › peer-review

Voxel-wise quantification of myocardial blood flow with cardiovascular magnetic resonance: effect of variations in methodology and validation with positron emission tomography.

Miller, C. A., Naish, J. H., Ainslie, M. P., Tonge, C., Tout, D., Arumugam, P., Banerji, A., Egdell, R. M., Clark, D., Weale, P., Steadman, C. D., McCann, G. P., Ray, S. G., Parker, G. J. M. & Schmitt, M., 24 Jan 2014, In: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 16, 1, 11.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume

Miller, C. A., Naish, J. H., Bishop, P., Coutts, G., Clark, D., Zhao, S., Ray, S. G., Yonan, N., Williams, S. G., Flett, A. S., Moon, J. C., Greiser, A., Parker, G. J. M. & Schmitt, M., May 2013, In: Circulation: Cardiovascular Imaging. 6, 3, p. 373-383 10 p.

Research output: Contribution to journal › Article › peer-review

R1 and R2* changes in the human placenta in response to maternal oxygen challenge

Huen, I., Morris, D. M., Wright, C., Parker, G. J. M., Sibley, C. P., Johnstone, E. D. & Naish, J. H., Nov 2013, In: Magnetic Resonance in Medicine. 70, 5, p. 1427-1433 6 p.

Research output: Contribution to journal › Article › peer-review

2012

DCE-MRI model selection for investigating disruption of microvascular function in livers with metastatic disease

Parker, G., Banerji, A., Naish, J. H., Watson, Y., Jayson, G. C., Buonaccorsi, G. A. & Parker, G. J. M., Jan 2012, In: Journal of Magnetic Resonance Imaging. 35, 1, p. 196-203 7 p.

Research output: Contribution to journal › Article › peer-review

2011

Comparison of dynamic contrast-enhanced MRI and dynamic contrast-enhanced CT biomarkers in bladder cancer

Naish, J. H., Mcgrath, D., Bains, L., Passera, K., Roberts, C., Watson, Y., Cheung, S., Taylor, M., Logue, J. P., Buckley, D., Tessier, J., Young, H., Waterton, J. C. & Parker, G., Jul 2011, In: Magnetic Resonance in Medicine. 66, 1, p. 219-226 7 p.

Research output: Contribution to journal › Article › peer-review

2010

Measurement of arterial plasma oxygenation in dynamic oxygen-enhanced MRI

Parker, G., Kershaw, L. E., Naish, J. H., McGrath, D. M., Waterton, J. C. & Parker, G. J. M., Dec 2010, In: Magnetic Resonance in Medicine. 64, 6, p. 1838-1842 4 p.

Research output: Contribution to journal › Article › peer-review

Multiple-bolus dynamic contrast-enhanced MRI in the pancreas during a glucose challenge

Naish, J., Waterton, J., Hutchinson, C., Caunce, A., Roberts, C., Hockings, P. D., Taylor, C. J. & Parker, G. J. M., Sept 2010, In: Journal of magnetic resonance imaging : JMRI. 32, 3, p. 622-628 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Tracer kinetic analysis of dynamic contrast-enhanced MRI and CT bladder cancer data: A preliminary comparison to assess the magnitude of water exchange effects

Waterton, J., Bains, L. J., McGrath, D. M., Naish, J. H., Cheung, S., Watson, Y., Taylor, M. B., Logue, J. P., Parker, G. J. M., Waterton, J. C. & Buckley, D. L., Aug 2010, In: Magnetic Resonance in Medicine. 64, 2, p. 595-603 8 p.

Research output: Contribution to journal › Article › peer-review

2009

Comparison of normal tissue R1 and R*2 modulation by oxygen and carbogen

O'Connor, J. P. B., Naish, J. H., Jackson, A., Waterton, J. C., Watson, Y., Cheung, S., Buckley, D. L., McGrath, D. M., Buonaccorsi, G. A., Mills, S. J., Roberts, C., Jayson, G. C. & Parker, G. J. M., Jan 2009, In: Magnetic Resonance in Medicine. 61, 1, p. 75-83 8 p.

Research output: Contribution to journal › Article › peer-review

Josephine Naish

Research output

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