Judi Allen
  • AV Hill Building, Oxford Road

    M13 9PT Manchester

    United Kingdom

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Personal profile

Biography

Judi Allen has a B.Sc. from Bates College, Maine and following several years in the Biotech industry, obtained her PhD from University of California, Berkeley in 1991.  She went to Imperial College, London for her postdoc and subsequently moved to Edinburgh, where she established her own group with an MRC Senior Fellowship in 1997.  In 2005, Judi became Professor of Immunobiology and in 2016 joined the Faculty of Life Sciences at the University of Manchester.  She is also a Fellow of the Royal Society of Edinburgh, a Fellow of the Royal Society of Biology, a Fellow of the Academy of Medical Sciences and a member of EMBO.  Judi was elected a Fellow of the Royal Society in 2023.  

 

Research interests

The Allen laboratory investigates the host immune response to parasite infection with a particular focus on type 2 immunity, the response mammals characteristically make to large multicellular parasites (helminths). A major research theme of the lab has been to investigate the function of macrophages activated by type 2 cytokines and their role in anti-helminth immunity.    Prof Allen’s research interests include the relationship of anti-helminth immunity to wound repair pathways, and understanding the challenges faced by the immune system during co-infection with both micro and macroparasites. 

My group

Lab Members (start date):

Brian Chan (May 2016) 

James Parkinson (Mar 2017)

Pedro Papotto (Oct 2019)

Georgia Baldwin (Oct 2020)

Lili Zhang (Jan 2022)

Becky Dodd (w/ Tara Sutherland & Tony Day)

Hannah Tompkins (w/ Tara Sutherland)

Mariana Suárez (Feb 2023) from Alvaro Diaz lab, Uruguay

Recent Lab Alumni:

Stella Pearson (2017 - 2022)

Hannah Smith (2021 - 2022)

Jesuthas Ajendra (2016 - 2021)

Conor Finlay (2017 - 2021)

Alistair Chenery (2016 - 2020)

Lab Associates:

Tara Sutherland

Dominik Rückerl 

 

Overview

The Allen laboratory studies the interaction between helminth parasites and their hosts. We aim to understand the function of the ‘type 2’ immune response typically induced in response to helminths. We are particularly interested in macrophages activated in the ‘type 2’ environment.  We are funded by the Medical Research Council and the Wellcome Trust. 
 
Please see recent key papers: 
 

Sutherland, Dyer, Allen. Science.  The extracellular matrix and the immune system: A mutually dependent relationship.  

Allen.  Annual Review of Immunology.  IL-4 and IL-13: Regulators and Effectors of Wound Repair.  

Donlan et al. JCI Insight. IL-13 is a driver of COVID-19 severity

Ajendra et al. Mucosal Immunology. IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection

 

 
 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

External positions

Honorary Professor, University of Edinburgh

15 Feb 2016 → …

Research Beacons, Institutes and Platforms

  • Lydia Becker Institute

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