Research output per year
Research output per year
Personal profile
Biography
Dr Julian Matthews studied mathematics before completing a Ph.D. in automotive engineering, both at Warwick University in the UK. Since then he has more than 25 years’ experience in medical imaging, specialising in Positron Emission Tomography methodology. He has worked for a number of academic organisations (MRC cyclotron unit – Hammersmith, Wolfson Brain Imaging Centre – Cambridge) and for the pharmaceutical company GlaxoSmithKline. In January 2005, he returned to academia at the University of Manchester and is currently within the Division of Neuroscience and Experimental Psychology. In addition to conducting research into medical imaging methods, he lectures undergraduate physics students and master students in two M.Sc. courses, Imaging Science and Neuroimaging for Clinical and Cognitive Neuroscience.
Research interests
Current research interests include:
- The application of PET imaging to drug development.
- The development of less invasive and arduous scanning techniques whilst maintaining data quality.
- Methodological development in improving signal to noise of PET data, including image reconstruction, kinetic modelling, and methods to optimise data acquisition.
- The development and application of combined PET-MR scanners.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Digital Futures
- Christabel Pankhurst Institute
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Oxygen-enhanced MRI detects incidence, onset and heterogeneity of radiation-induced hypoxia modification in HPV-associated oropharyngeal cancer
Dubec, M., Price, J., Berks, M., Gaffney, J., Little, R., Porta, N., Sridharan, N., Datta, A., McHugh, D., Hague, C., Cheung, S., Manoharan, P., Van Herk, M., Choudhury, A., Matthews, J., Parker, G., Buckley, D., Harrington , K. J., Mcpartlin, A. & O'Connor, J., 15 Aug 2024, (E-pub ahead of print) In: Clinical Cancer Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Downloads (Pure) -
Dependency of proton MR spectroscopy neuro-metabolite concentrations on grey matter fraction and location in the healthy human brain.
Goncalves, A. J., Matthews, J., Haroon, H., Parkes, L., Asselin, M.-C. & Williams, S. R., 19 May 2023, Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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First-in-Human Technique Translation of Oxygen-Enhanced MRI to an MR Linac System in Patients with Head and Neck Cancer
Dubec, M. J., Buckley, D. L., Berks, M., Clough, A., Gaffney, J., Datta, A., McHugh, D. J., Porta, N., Little, R. A., Cheung, S., Hague, C., Eccles, C. L., Hoskin, P. J., Bristow, R. G., Matthews, J. C., van Herk, M., Choudhury, A., Jm Parker, G., McPartlin, A. & Pb O'Connor, J., 2 Mar 2023, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. p. 109592Research output: Contribution to journal › Article › peer-review
Open Access -
Advanced quantitative evaluation of PET systems using the ACR phantom and NiftyPET software
Markiewicz, P. J., da Costa-Luis, C., Dickson, J., Barnes, A., Krokos, G., MacKewn, J., Clark, T., Wimberley, C., MacNaught, G., Yaqub, M. M., Gispert, J. D., Hutton, B. F., Marsden, P., Hammers, A., Reader, A. J., Ourselin, S., Herholz, K., Matthews, J. & Barkhof, F., 1 May 2022, In: Medical Physics. 49, 5, p. 3298-3313 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Improving cerebral blood flow measurements from dynamic [15O]H2O PET study using complementary frame reconstruction and isotope-specific resolution modelling
Goncalves, A., Krokos, G., Jones, O., Xia, Y., Djoukhadar, I., Jackson, A., Matthews, J., Anton-Rodriguez, J. & Asselin, M., 22 Sept 2022, European Journal of Nuclear Medicine and Molecular Imaging. SUPPL 1 ed. Vol. 49. p. S164-S164 1 p. (European Journal of Nuclear Medicine and Molecular Imaging).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
Projects
- 4 Finished
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Quantification of Vascular and Neuronal Pathology in Dementia Using PET and MRI.
Parker, G. (PI), Asselin, M.-C. (CoI), Boutin, H. (CoI), Burns, A. (CoI), Herholz, K. (CoI), Matthews, J. (CoI), Parkes, L. (CoI) & Williams, S. (CoI)
1/01/15 → 28/02/19
Project: Research
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CRUK Imaging Centres.
Jackson, A. (PI), Asselin, M.-C. (CoI), Coope, D. (CoI), Dive, C. (CoI), Faivre-Finn, C. (CoI), Herholz, K. (CoI), Hinz, R. (CoI), Illidge, T. (CoI), Manoharan, P. (CoI), Marais, R. (CoI), Matthews, J. (CoI), McMahon, A. (CoI), O'Connor, J. (CoI), Parker, G. (CoI), Stivaros, S. (CoI), Thacker, N. (CoI), Williams, K. (CoI) & Withers, P. (CoI)
1/12/13 → 30/11/19
Project: Research
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GLOBAL- Manchester Image Reconstruction and ANalysis (MIRAN): Step jumps in imaging by Global Exchange of user pull and method push
Lionheart, W. (PI), Cootes, T. (CoI), Dorn, O. (CoI), Gray, N. (CoI), Grieve, B. (CoI), Haigh, S. (CoI), Harris, D. (CoI), Hollis, C. (CoI), Matthews, J. (CoI), Mccann, H. (CoI), Parker, G. (CoI), Villegas Velasquez, R. (CoI) & Withers, P. (CoI)
1/04/12 → 31/03/13
Project: Research
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EURIPIDES: European research initiative to develop imaging probes for early in-vivo diagnosis and evaluation of response to therapeutic substances (EURIPIDES)
Asselin, M.-C. (PI), Brown, G. (CoI), Herholz, K. (CoI), Jackson, A. (CoI), Matthews, J. (CoI), McMahon, A. (CoI) & Talbot, P. (CoI)
1/02/08 → 31/07/12
Project: Research
Datasets
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SIRF: Synergistic Image Reconstruction Framework
Ovtchinnikov, E. (Contributor), Brown, R. (Contributor), Kolbitsch, C. (Contributor), Pasca, E. (Contributor), da Costa-Luis, C. (Contributor), Gillman, A. G. (Contributor), Thomas, B. A. (Contributor), Efthimiou, N. (Contributor), Mayer, J. (Contributor), Wadhwa, P. (Contributor), Ehrhardt, M. J. (Contributor), Ellis, S. (Contributor), Jørgensen, J. S. (Contributor), Matthews, J. (Contributor), Prieto, C. (Contributor), Reader, A. J. (Contributor), Tsoumpas, C. (Contributor), Turner, M. (Contributor), Atkinson, D. (Contributor) & Thielemans, K. (Contributor), Mendeley Data, 9 Jan 2020
DOI: 10.17632/s45f5jh55j.1, https://data.mendeley.com/datasets/s45f5jh55j
Dataset