Kerrie Marie

Accepting PhD Students

PhD projects

https://www.findaphd.com/phds/project/bbsrc-dtp-looking-into-the-crystal-ball-uncovering-predictive-mechanical-cues-for-cell-choices-in-development-and-disease/?p147525

Personal profile

Overview

My research retains a strong modelling theme - spanning developmental biology, cancer biology and computational biology. My multidisciplinary approach explores embryonic melanocyte progenitor programs of the neural crest lineage to shed new light on embryonic lineage cell states that are re-acquired during melanoma metastasis. 

Biography

Kerrie completed her PhD at the MRC Human Genetics Unit, Edinburgh, supported by the University of Edinburgh in 2013. her PhD work focussed on developmental models of embryonic melanocyte development and regeneration in the zebrafish model, with a view to uncovering novel pathways that are regulated in development but dysregulated in disease. Her work was centred around chemical-genetics techniques, drug screening and timelapse confocal imaging of the melanocytic lineage. From these studies Kerrie became fascinated with how melanocyte lineage pathways are dysregulated in melanoma progression. From here she moved to the National Cancer Institute at the National Institutes of Health in 2014 to develop my expertise in mouse models of melanoma metastasis and therapy resistance. Kerrie's postdoctoral work centred on mouse experimental metastases models, models of Immune Checkpoint Blockade (ICB) resistance, 'Omics analyses of melanoblast development and melanoma disease progression, fundamental molecular biology of Endoplasmic Reticulum (ER) stress biology, single-cell technologies and computational analysis.

In 2022 Kerrie moved to the multidisciplinary environment of the University of Manchester as a Wellcome Trust ISSF Fellow, later being awarded with a prestigious University of Manchester Dean's Prize award. Kerrie's lab focuses on understanding cell fate decisions in the embryonic melanocyte precursors of the neural crest and using these insights to shed new light on embryonic lineage cell states that are re-acquired during melanoma metastasis.

Opportunities

I am accepting applications from all excellent candidates for the below fully-funded, multidisciplinary position:

https://www.findaphd.com/phds/project/bbsrc-dtp-looking-into-the-crystal-ball-uncovering-predictive-mechanical-cues-for-cell-choices-in-development-and-disease/?p147525

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Beacons, Institutes and Platforms

  • Cancer

Keywords

  • Melanoma
  • Metastasis
  • Melanoblast
  • Melanocyte

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