Research output per year
Research output per year
- 28 results
Search results
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2023
A three-gene leukaemic stem cell signature score is robustly prognostic in chronic myelomonocytic leukaemia
Wang, Y.-H., Yao, C.-Y., Lin, C.-C., Gurashi, K., Amaral, F. M. R., Bossenbroek, H., Jerez, A., Somervaille, T. C. P., Binder, M., Patnaik, M. M., Hou, H.-A., Chou, W.-C., Batta, K., Wiseman, D. H. & Tien, H.-F., 1 Apr 2023, In: British Journal of Haematology. 201, 2, p. 302-307 6 p.Research output: Contribution to journal › Article › peer-review
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Higher MDMX expression was associated with hypomethylating agent resistance and inferior survival in MDS patients, inferring it a potential therapeutic target
Wang, Y.-H., Lin, C.-C., Gurashi, K., Wingelhofer, B., Amaral, F. M. R., Yao, C.-Y., Hsieh, H. T., Liu, M. C., Hou, H.-A., Chou, W.-C., Batta, K., Wiseman, D. H. & Tien, H.-F., Dec 2023, In: Leukemia. 37, 12, p. 2507-2511 5 p.Research output: Contribution to journal › Article › peer-review
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Increased Inflammasome Activation Is Associated with Aging and Chronic Myelomonocytic Leukemia Disease Severity
Andina, N., de Meuron, L., Schnegg-Kaufmann, A. S., Sarangdhar, M. A., Ansermet, C., Bombaci, G., Batta, K., Keller, N., Porret, N. A., Angelillo-Scherrer, A., Bonadies, N. & Allam, R., 1 Mar 2023, In: Journal of immunology (Baltimore, Md. : 1950). 210, 5, p. 580-589 10 p.Research output: Contribution to journal › Article › peer-review
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Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils
Huerga Encabo, H., Aramburu, I. V., Garcia-Albornoz, M., Piganeau, M., Wood, H., Song, A., Ferrelli, A., Sharma, A., Minutti, C. M., Domart, M.-C., Papazoglou, D., Gurashi, K., Llorian Sopena, M., Goldstone, R., Fallesen, T., Wang, Q., Ariza-McNaughton, L., Wiseman, D. H., Batta, K. & Gupta, R. & 2 others, , 1 Jun 2023, In: Cell Stem Cell. 30, 6, p. 781-799.e9Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths
Cortés-López, M., Chamely, P., Hawkins, A. G., Stanley, R. F., Swett, A. D., Ganesan, S., Mouhieddine, T. H., Dai, X., Kluegel, L., Chen, C., Batta, K., Furer, N., Vedula, R. S., Beaulaurier, J., Drong, A. W., Hickey, S., Dusaj, N., Mullokandov, G., Stasiw, A. M. & Su, J. & 14 others, , 7 Sept 2023, In: Cell Stem Cell. 30, 9, p. 1262-1281.e8Research output: Contribution to journal › Article › peer-review
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2022
Integrative Analysis of Blast Phase Chronic Myelomonocytic Leukemia Reveals Distinct Transformation Phenotypes Predictive of Drug Response
Gurashi, K., Wang, Y.-H., Somervaille, T. C. P., Batta, K. & Wiseman, D. H., 2022, p. 213-214. 2 p.Research output: Contribution to conference › Abstract
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2021
Divergent clonal evolution of blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia from a shared TET2-mutated origin
Batta, K., Bossenbroek, H. M., Pemmaraju, N., Wilks, D. P., Chasty, R., Dennis, M., Milne, P., Collin, M., Beird, H. C., Taylor, J., Patnaik, M. M., Cargo, C. A., Somervaille, T. C. P. & Wiseman, D. H., Nov 2021, In: Leukemia. 35, 11, p. 3299-3303 5 p.Research output: Contribution to journal › Article › peer-review
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Multiomic Single-Cell Sequencing Reveals Patterns of Disease Evolution and Acute Transformation in Chronic Myelomonocytic Leukaemia
Gurashi, K., Weightman, J., Baker, S. M., Rouault-Pierre, K., Breitweister, W., Somervaille, T. C. P., Batta, K. & Wiseman, D. H., 2021, p. 2586-2586. 1 p.Research output: Contribution to conference › Abstract
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The Dynamic Interface Between the Bone Marrow Vascular Niche and Hematopoietic Stem Cells in Myeloid Malignancy
Mosteo, L., Storer, J., Batta, K., Searle, E., Duarte, D. & Wiseman, D., 11 Mar 2021, In: Frontiers in cell and developmental biology. 9, 635189.Research output: Contribution to journal › Review article › peer-review
Open AccessFile124 Downloads (Pure) -
2020
Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome
Wiseman, D., Baker, S. M., Dongre, A., Gurashi, K., Storer, J., Somervaille, T. & Batta, K., 4 Aug 2020, In: EBioMedicine. 58, 102904.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis
Yoshimi, A. (Lead), Lin, K.-T. (Lead), Wiseman, D. (Lead), Rahman, M., Pastore, A., Wang, B., Lee, S., Micol, J.-B., Zhang, X., de Botton, S., Penard-Lacronique, V., Stein, E., Cho, H., Miles, R., Inoue, D., Albrecht, T., Somervaille, T., Batta, K., Amaral, F. & Simeoni, F. & 9 others, , 2 Oct 2019, In: Nature. 574, p. 273-277Research output: Contribution to journal › Letter › peer-review
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2018
Transcriptomic rationale for synthetic lethality-targeting ERCC1 and CDKN1A in chronic myelomonocytic leukaemia
Hurtado, A. M., Luengo-gil, G., Chen-liang, T. H., Amaral, F., Batta, K., Palomo, L., Lumbreras, E., Przychodzen, B., Caparros, E., Amigo, M. L., Dıez-campelo, M., Zamora, L., Salido Fierrez, E. J., Maciejewski, J. P., Ortuño, F. J., Vicente, V., Del Canizo, M., Sole, F., Ferrer-marin, F. & Wiseman, D. H. & 1 others, , Aug 2018, In: British Journal of Haematology. 182, 3, p. 373-383 11 p.Research output: Contribution to journal › Article › peer-review
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2017
Primitive erythrocytes are generated from hemogenic endothelial cells
Stefanska, M., Batta, K., Patel, R., Florkowska, M., Kouskoff, V. & Lacaud, G., 2017, In: Scientific Reports. 7Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Concise Review: Recent Advances in the In Vitro Derivation of Blood Cell Populations
Batta, K., Menegatti, S., Garcia-Alegria, E., Florkowska, M., Lacaud, G. & Kouskoff, V., Oct 2016, In: Stem Cells Translational Medicine. 5, 10, p. 1330-1337 8 p.Research output: Contribution to journal › Article › peer-review
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Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation
Goode, D. K., Obier, N., Vijayabaskar, M. S., Lie-A-Ling, M., Lilly, A., Hannah, R., Lichtinger, M., Batta, K., Florkowska, M., Patel, R., Challinor, M., Wallace, K., Gilmour, J., Assi, S. A., Cauchy, P., Hoogenkamp, M., Westhead, D. R., Lacaud, G., Kouskoff, V. & Göttgens, B. & 1 others, , 7 Mar 2016, In: Developmental cell. 36, 5, p. 572-587 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Emerging concepts for the in vitro derivation of murine haematopoietic stem and progenitor cells
Garcia-Alegria, E., Menegatti, S., Batta, K., Cuvertino, S., Florkowska, M. & Kouskoff, V., 2016, In: FEBS Letters.Research output: Contribution to journal › Article › peer-review
Open AccessFile114 Downloads (Pure) -
Erratum: Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage (Scientific Reports 6 (25917) DOI: 10.1038/srep25917)
Garcia Alegria, E., Iliut, M., Stefanska, M., Silva, C., Heeg, S., Kimber, S., Kouskoff, V., Lacaud, G., Vijayaraghavan, A. & Batta, K., 4 Jul 2016, In: Scientific Reports. 6, 28723.Research output: Contribution to journal › Commentary/debate › peer-review
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Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage
Garcia Alegria, E., Iliut, M., Stefanska, M., Silva, C., Heeg, S., Kimber, S., Kouskoff, V., Lacaud, G., Vijayaraghavan, A. & Batta, K., 2016, In: Scientific Reports. 6, 25917.Research output: Contribution to journal › Article › peer-review
Open Access9 Downloads (Pure) -
New insights into the regulation by RUNX1 and GFi1(s) proteins of the endothelial to hematopoietic transition generating primordial hematopoietic cells
Thambyrajah, R., Patel, R., Mazan, M., Lie-A-Ling, M., Lilly, A. J., Eliades, A., Menegatti, S., Garcia Alegria, E., Florkowska, M., Batta, K., Kouskoff, V. & Lacaud, G., 17 Aug 2016, In: Cell Cycle. 15, 16, p. 2108-2114 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells
Batta, K., Florkowska, M., Kouskoff, V. & Lacaud, G., 26 Nov 2014, In: Cell Reports. 9, 5, p. 1871-1884 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile250 Downloads (Pure) -
2012
Genome-wide nucleosome specificity and directionality of chromatin remodelers
Yen, K., Vinayachandran, V., Batta, K., Koerber, R. T. & Pugh, B. F., 22 Jun 2012, In: Cell. 149, 7, p. 1461-1473 13 p.Research output: Contribution to journal › Article › peer-review
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2010
Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17
Selvi, B. R., Batta, K., Kishore, A. H., Mantelingu, K., Varier, R. A., Balasubramanyam, K., Pradhan, S. K., Dasgupta, D., Sriram, S., Agrawal, S. & Kundu, T. K., 5 Mar 2010, In: The Journal of biological chemistry. 285, 10, p. 7143-7152 10 p.Research output: Contribution to journal › Article › peer-review
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2009
Human transcriptional coactivator PC4 stimulates DNA end joining and activates DSB repair activity
Batta, K., Yokokawa, M., Takeyasu, K. & Kundu, T. K., 23 Jan 2009, In: Journal of molecular biology. 385, 3, p. 788-99 12 p.Research output: Contribution to journal › Article › peer-review
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2007
Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications
Batta, K. & Kundu, T. K., Nov 2007, In: Molecular and Cellular Biology. 27, 21, p. 7603-14 12 p.Research output: Contribution to journal › Article › peer-review
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p53 regulates its own activator: transcriptional co-activator PC4, a new p53-responsive gene
Kishore, A. H., Batta, K., Das, C., Agarwal, S. & Kundu, T. K., 15 Sept 2007, In: The Biochemical Journal. 406, 3, p. 437-44 8 p.Research output: Contribution to journal › Article › peer-review
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Reversible acetylation of non histone proteins: role in cellular function and disease
Batta, K., Das, C., Gadad, S., Shandilya, J. & Kundu, T. K., 2007, In: Sub-cellular biochemistry. 41, p. 193-212 20 p.Research output: Contribution to journal › Article › peer-review
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2006
Transcriptional coactivator PC4, a chromatin-associated protein, induces chromatin condensation
Das, C., Hizume, K., Batta, K., Kumar, B. R. P., Gadad, S., Ganguly, S., Lorain, S., Verreault, A., Sadhale, P. P., Takeyasu, K. & Kundu, T. K., Nov 2006, In: Molecular and Cellular Biology. 26, 22, p. 8303-15 13 p.Research output: Contribution to journal › Article › peer-review
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2005
Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis
Sadasivam, S., Gupta, S., Radha, V., Batta, K., Kundu, T. K. & Swarup, G., 20 Jan 2005, In: Oncogene. 24, 4, p. 627-36 10 p.Research output: Contribution to journal › Article › peer-review