Personal profile
Overview
Email: [email protected]
Kylie is a Lecturer in Reproductive Immunology, within the Maternal and Fetal Health Research Centre at the University of Manchester. Her research interests are the role of the innate immune system in pregnancy, menstruation and womens health.
Kylie completed her PhD in 2013 at the University of Surrey, where she studied the effects of extracellular ATP in blood and lung derived dendritic cells. She then took up a post-doctoral position at the National Heart and Lung Institute at Imperial College London, where she studied the mechanisms of impaired macrophage phagocytosis in Chronic Obstructive Pulmonary Disease (COPD). In 2019, Kylie was awarded a post-doctoral fellowship from the Alpha-1 Foundation, and moved to the University of Birmingham. This fellowship studied monocyte and macrophage function in AATD, a genetic cause of COPD. During her fellowship, Kylie studied neutrophil function in COVID-19, and recieved funding from the Dunhill Trust to study macrophage function in ageing and frailty. During this time, she developed an interest in the immunology of pregnancy, and obtained funding from the Preeclampsia Foundation to study decidual macrophage function in preeclasmpsia.
In September 2024, Kylie joined the University of Manchester as a Lecturer in Maternal and Fetal Health. Her research interests remain the immunology of pregnancy, as well as maternal and womens health.
Education/Academic qualification
Master of Teaching and Learning, Postgraduate Certificate of Higher Education, University of Birmingham
Award Date: 1 Oct 2024
Doctor of Philosophy, Immunomodulatory effects of extracellular ATP on human blood and lung derived dendritic cells, University of Surrey
1 Oct 2008 → 30 Sept 2012
Award Date: 13 Jan 2013
Bachelor of Science, Pharmacology, University of Portsmouth
Award Date: 31 Jul 2008
External positions
Honorary Senior Research Fellow, University of Birmingham
1 Sept 2024 → 1 Sept 2027
Areas of expertise
- QR180 Immunology
- Innate immunology
- Macrophages
- Neutrophils
- Monocytes
- RG Gynecology and obstetrics
- Pregnancy
- Womens Health
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
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Hospitalised older adults with community-acquired pneumonia and sepsis have dysregulated neutrophil function but preserved glycolysis
Grudzinska, F. S., Faniyi, A. A., Belchamber, K., Chen, C., Stockley, R., Jasper, A., Parekh, D., Sapey, E., Scott, A. & Thickett, D. R., 16 Dec 2024, In: Thorax.Research output: Contribution to journal › Article › peer-review
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Macrophages and the microbiome in chronic obstructive pulmonary disease
Sandhu, K. K., Scott, A., Tatler, A. L., Belchamber, K. B. R. & Cox, M. J., Oct 2024, In: European Respiratory Review.Research output: Contribution to journal › Article › peer-review
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Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol
Quarton, S., McGee, K., Cumley, N., Behruznia, M., Jeff, C., Belchamber, K., Cox, M. J., thickett, D., Scott, A., Parekh, D., McNally, A. & Sapey, E., 29 Mar 2024, In: PLoS ONE. 19, 3, e0298425.Research output: Contribution to journal › Article › peer-review
Open Access -
Dysregulated neutrophil phenotype and function in hospitalised non-ICU COVID-19 pneumonia
Belchamber, K., Thein, O. S., Hazeldine, J., Grudzinska, F. S., Faniyi, A., Jasper, A., Yip, K. P., Crowley, L. E., Lugg, S. T., Sapey, E., Parekh, D., thickett, D. & Scott, A., 16 Sept 2022, In: Cells.Research output: Contribution to journal › Article › peer-review
Open Access -
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease
Lodge, K. M., Vassallo, A., Long, M., Tong, Z., Agha-Jaffa, D., Paschalaki, K., Green, C. E., Belchamber, K., Ridger, V. C., Stockley, R. A., Sapey, E., Summers, C., Cowburn, A. S., Chilvers, E. R. & Condliffe, A. M., 15 Apr 2022, In: American Journal of Respiratory and Critical Care Medicine .Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Active
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Maternal & Fetal Health Research Centre
Stevens, A. (PI), Heazell, A. (PI), Tower, C. (PI), Brison, D. (PI), Johnstone, E. (PI), Cottrell, E. (PI), Mann, E. (PI), Ingram, E. (PI), Crocker, I. (PI), Chernyavsky, I. (PI), Myers, J. (PI), Aplin, J. (PI), Higgins, L. (PI), Harris, L. (PI), Dilworth, M. (PI), Westwood, M. (PI), Whitworth, M. (PI), Desforges, M. (PI), Brownbill, P. (PI), Ruane, P. (PI), Sturmey, R. (PI), Worton, S. (PI), Greenwood, S. (PI), Sibley, C. (PI), Belchamber, K. (PI), Palin, V. (PI), Povey, A. (PI), Ormesher, L. (PI) & Perchard, R. (PI)
1/09/18 → 31/12/35
Project: Research