Research output per year
Research output per year
- 19 results
Search results
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2023
Add-on therapy for pulmonary fibrosis, a forthcoming era with implications for practice: the BI 101550 and RELIEF trials
Planas-Cerezales, L., Fabbri, L. & Pearmain, L., 12 Sept 2023, In: Breathe. 19, 3, 9 p., 230090.Research output: Contribution to journal › Article › peer-review
Open Access -
Changes in lung epithelial cell volatile metabolite profile induced by pro-fibrotic stimulation with TGF-β1
Hayton, C., Ahmed, W., Cunningham, P., Piper-Hanley, K., Pearmain, L., Chaudhuri, N., Leonard, C., Blaikley, J. & Fowler, S. J., 1 Oct 2023, In: Journal of Breath Research. 17, 4, 046012.Research output: Contribution to journal › Article › peer-review
Open Access -
Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID
CIRCO, Scott, N. A., Pearmain, L., Knight, S. B., Brand, O., Morgan, D. J., Jagger, C., Harbach, S., Khan, S., Shuwa, H. A., Franklin, M., Kästele, V., Williams, T., Prise, I., McClure, F. A., Hackney, P., Smith, L., Menon, M., Konkel, J. E. & Lawless, C. & 18 others, , 11 May 2023, (E-pub ahead of print) In: The European respiratory journal. 61, 5, 20 p., 2202226.Research output: Contribution to journal › Article › peer-review
Open Access -
PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
Jokl, E., Mullan, A. F., Simpson, K., Birchall, L., Pearmain, L., Martin, K., Pritchett, J., Raza, S., Shah, R., Hodson, N. W., Williams, C. J., Camacho, E., Zeef, L., Donaldson, I., Athwal, V. S., Hanley, N. A. & Piper Hanley, K., 28 Nov 2023, In: Cell Reports. 42, 11, 113414.Research output: Contribution to journal › Article › peer-review
Open Access -
Rapid Generation of Pulmonary Organoids from Induced Pluripotent Stem Cells by Co-Culturing Endodermal and Mesodermal Progenitors for Pulmonary Disease Modelling
Mitchell, A., Yu, C., Zhao, X., Pearmain, L., Shah, R., Hanley, K. P., Felton, T. & Wang, T., 18 May 2023, (E-pub ahead of print) In: Biomedicines. 11, 5, 1476.Research output: Contribution to journal › Article › peer-review
Open AccessFile70 Downloads (Pure) -
2022
Large scale clinical trials: lessons from the COVID-19 pandemic
Horsley, A., Pearmain, L., Knight, S., Schindler, N., Wang, R., Bennett, M., Robey, R., Davies, J. C., Djukanovic, R., Heaney, L. G., Hussell, T., Marciniak, S. J., McGarvey, L., Porter, J. C., Wilkinson, T., Brightling, C. & Ho, L.-P., 14 Jun 2022, In: BMJ Open Respiratory Research. 9, 1, e001226.Research output: Contribution to journal › Article › peer-review
Open Access -
Sox9 Regulates Alveolar Damage and Extracellular Matrix Secretion By Fibroblasts in Idiopathic Pulmonary Fibrosis: Downstream Secreted Proteins Are Promising Biomarkers
Pearmain, L., Jokl, E., Simpson, K., Birchall, L., Rivera-Ortega, P. & Hanley, K., Nov 2022, In: Thorax. 77, p. A66-A67 2 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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2021
Alterations in T and B cell function persist in convalescent COVID-19 patients
Shuwa, H. A., Shaw, T., Knight, S., Wemyss, K., Mcclure, F., Pearmain, L., Prise, I., Jagger, C., Morgan, D., Khan, S., Brand, O., Mann, E., Ustianowski, A., Diar Bakerly, N., Dark, P., Brightling, C. E., Brij, S., Felton, T., Simpson, A. & Grainger, J. & 3 others, , 11 Jun 2021, In: Med. 2, 6, p. 720-+Research output: Contribution to journal › Article › peer-review
Open Access -
Conventional oxygen therapy versus CPAP as a ceiling of care in ward-based patients with COVID-19: a multi-centre cohort evaluation
Goodley, P., Wilson, J., Taylor, R., Nixon, J., Redfern, J., Whittemore, P., Gaddah, M., Kavuri, K., Haley, A., Denny, P., Withers, C., Robey, R. C., Logue, C., Dahanayake, N., Hui Min, D. S., Coles, J., Deshmukh, M. S., Ritchie, S., Malik, M. & Abdelaal, H. & 13 others, , 1 Oct 2021, In: EClinicalMedicine. 40, 1 p., 101122.Research output: Contribution to journal › Article › peer-review
Open Access -
P058 Persistence of neutrophil abnormalities in COVID-19 convalescence
Williams, T., Kästele, V., Mann, E., Knight, S., Menon, M., Jagger, C., Khan, S., Konkel, J., Shaw, T., Rattray, M., Pearmain, L., Horsley, A., Ustianowski, A., Prise, I. & Hussell, T., Apr 2021, In: Rheumatology (Oxford, England).Research output: Contribution to journal › Article
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P168 Patient symptoms following discharge from hospital after COVID-19 Pneumonia
Pearmain, L., Avram, C., Yioe, V., Webb, P., Margaritopoulos, G., Rivera-Ortega, P., Chaudhuri, N. & Blaikley, J., Feb 2021.Research output: Contribution to conference › Paper › peer-review
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RESEARCH FOR ALL: THE IMPACT OF NWCORR, A TRAINEE RESEARCH COLLABORATIVE
Randles, V., Bradley, P., Pearmain, L., Frost, F. & Ashish, A., 1 Nov 2021, In: Thorax. 76, p. A162-A162Research output: Contribution to journal › Meeting Abstract › peer-review
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2020
Lessons of the month 1: Salbutamol induced lactic acidosis: clinically recognised but often forgotten.
Pearmain, L., Gupta, R. & Bright-Thomas, R., 15 Jan 2020, In: Clinical medicine (London, England).Research output: Contribution to journal › Article › peer-review
Open Access -
Longitudinal immune profiling reveals distinct features of COVID-19 pathogenesis
Respiratory TRC, CIRCO, Mann, E. R., Menon, M., Knight, S. B., Konkel, J. E., Jagger, C., Shaw, T. N., Krishnan, S., Rattray, M., Ustianowski, A., Bakerly, N. D., Dark, P., Lord, G., Simpson, A., Felton, T., Ho, L. P., Feldmann, M., Grainger, J. R. & Hussell, T., 1 Jun 2020, medRxiv, 30 p.Research output: Preprint/Working paper › Preprint
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Recovery of monocyte exhaustion is associated with resolution of lung injury in COVID-19 convalescence
Scott, N., Knight, S., Pearmain, L., Brand, O., Morgan, D., Jagger, C., Khan, S., Hackney, P., Smith, L., Menon, M., Konkel, J., Shuwa, H., Franklin, M., Kästele, V. & CIRCO, 16 Oct 2020, Laurel Hollow, NY: medRxiv, 32 p.Research output: Preprint/Working paper › Preprint
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Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathy
CIRCO, 21 Aug 2020, medRxiv, (medRxiv).Research output: Preprint/Working paper › Working paper
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The utility of established prognostic scores in COVID-19 hospital admissions: A multi-centre prospective evaluation of CURB-65, NEWS2, and qSOFA
Bradley, P., Frost, F., Tharmaratnam, K., Wootton, D. G., Ahmad, M., Aigbirior, J., Bull, A., Cade, R., Grant, K., King, C., Kumar, A., Kutubuddin, F., Liatsikos, K., Mir, M. H., Nasr, E., Pearmain, L., Penfold, R., Raghunath, S., Randles, V. & Robinson, R. & 1 others, , 18 Jul 2020, In: BMJ Open Respiratory Research.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Persistent air leak after pulmonary transplantation
Pearmain, L., Krysiak, P., Blaikley, J. & Alaloul, M., 27 Jul 2017, In: BMJ Case Reports. 2017Research output: Contribution to journal › Article › peer-review
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SOX9 predicts progression towards cirrhosis in patients while its loss protects against liver fibrosis
Athwal, V., Pritchett, J., Llewellyn, J., Martin, K., Camacho, E., Raza, S., Phythian-Adams, A., Birchall, L., Mullan, A., Su, K., Pearmain, L., Dolman, G., Zaitoun, A. M., Friedman, S., MacDonald, A., Irving, W. L., Guha, I. N., Hanley, N. & Piper Hanley, K., 2017, In: EMBO Molecular Medicine .Research output: Contribution to journal › Article › peer-review
Open Access