Louise Carter

Search results

• 2023

  124MO A single centre experience of patients with rare cancers referred for early phase clinical trials

  Angelakas, A., Cook, N., Graham, D. M., Krebs, M., Thistlethwaite, F. & Carter, L., 22 Mar 2023, In: ESMO Open. 8, 1

  Research output: Contribution to journal › Meeting Abstract › peer-review

• 716TiP DETERMINE: A pioneering UK precision medicine trial for rare cancers

  Middleton, G., Marshall, L., Billingham, L., Duffus, K., Greystoke, A., Carter, L., Forster, M., Cook, N., Hargrave, D., Danson, S., Roxburgh, P., Beggs, A., Chaturvedi, A., Chesler, L., Sarmiento-Castro, A., Dive, C., Rothwell, D., Gath, J., Halford, S. & Krebs, M., 20 Oct 2023, In: Annals of Oncology. 34, p. S494-S495 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2022

  384P Concordance of genomic alterations in tumour tissue and ctDNA in patients with colorectal cancer referred for early phase trials

  Ramchander, N., Billy Graham Mariam, N., Rack, S., Shohdy, K., Franco, A., Thistlethwaite, F., Graham, D. M., Carter, L., Dransfield, S., Henshaw, A., Darlington, E., Rothwell, D., Burghel, G., Dive, C., Krebs, M. & Cook, N., 1 Sept 2022, In: Annals of Oncology. 33, p. S712

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Circulating tumor DNA (ctDNA) determinants of improved outcomes in patients (pts) with advanced solid tumors receiving the ataxia telangiectasia and Rad3-related inhibitor (ATRi), RP-3500, in the phase 1/2a TRESR trial (NCT04497116).

  Rosen, E., Silverman, I. M., Fontana, E., Lee, E. K., Spigel, D. R., Højgaard, M., Lheureux, S., Mettu, N. B., Carneiro, B. A., Carter, L., Plummer, E. R., Schonhoft, J. D., Ulanet, D., Manley, P., Reis-Filho, J. S., Xu, Y., Rimkunas, V., Koehler, M. & Yap, T. A., 2 Jun 2022, In: Journal of Clinical Oncology. 40, 16_suppl, p. 3082-3082 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Solid Malignant Neoplasm 100%
  • Circulating Tumor DNA 100%
  • Ataxia Telangiectasia 100%
  • Ataxia Telangiectasia and Rad3 Related 100%
  • Hematopoiesis 57%
• 2021

  1493P An evaluation of the psychological impact of early phase clinical trials in cancer patients

  Jittla, P., Graham, D., Zhou, C., Halliwell, J., O'Reilly, S., Aruketty, S., Azizi, A., Germetaki, T., Lowe, J., Little, M., Punnett, G., McMahon, P., Benson, L., Carter, L., Krebs, M., Thistlethwaite, F., Yorke, J. & Cook, N., 1 Sept 2021, In: Annals of Oncology. 32, p. S1097-S1098

  Research output: Contribution to journal › Meeting Abstract › peer-review

• 1849P Ethnicity and socioeconomic deprivation in early phase clinical trials in a UK tertiary referral centre

  Billy Graham Mariam, N., Rahman, R., Mistry, H., Aruketty, S., Adamson-Raieste, A., Church, M., Scott, J.-A., Carter, L., Thistlethwaite, F., Krebs, M., Cook, N. & Graham, D., 1 Sept 2021, In: Annals of Oncology. 32, p. S1247

  Research output: Contribution to journal › Meeting Abstract › peer-review

• 44P Value of comprehensive genomic profiling in pre-screening patients for NTRK fusion in STARTRK2 trial: Single centre experience

  Franco, A., Adamson-Raieste, A., Rahman, R., Pihlak, R., Peters, N., Scott, J.-A., Aruketty, S., Thomson, C., Dransfield, S., Henshaw, A., Ward, A., Cutts, T., Carter, L., Thistlethwaite, F., Cook, N., Graham, D. M., Stevenson, J. & Krebs, M., 1 Oct 2021, In: Annals of Oncology. 32, p. S1359

  Research output: Contribution to journal › Meeting Abstract › peer-review

• 560TiP A phase I/IIa study to evaluate the safety and efficacy of CCS1477, a first in clinic inhibitor of p300/CBP, as monotherapy in patients with selected molecular alterations

  Crabb, S., Plummer, R., Greystoke, A., Carter, L., Pacey, S., Walter, H., Coyle, V. M., Knurowski, T., Clegg, K., Ashby, F., Pegg, N., West, W., Brooks, N., Hughes, A. & de Bono, J., Sept 2021, In: Annals of Oncology. 32, p. S617

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Monotherapy 100%
  • Loss of Function Mutation 100%
  • Tumor Biopsy 66%
  • Breast Sarcoma 50%
  • Lethality 50%

• Differential response rates in early-phase cancer clinical trials (EPCCT).

  Rahman, R., Billy Graham Mariam, N., Mistry, H., Aruketty, S., Church, M., Adamson-Raieste, A., Scott, J.-A., Thistlethwaite, F., Krebs, M., Carter, L., Graham, D. & Cook, N., 28 May 2021, In: Journal of Clinical Oncology. 39, 15_suppl, p. 3133 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Lactate Dehydrogenase 100%
  • Hazard Analysis 100%
  • Electrocorticography 50%
• 2019

  A multidisciplinary-guided digital solution to data capture in early-phase clinical trials.

  Graham, D. M., Clarke, J., Wickert, G., Goodwin, L., Timmins, C., Chang, D., Walker, A., Rees, A., Stringer, S., Theis, A., Carter, L., Cook, N., Krebs, M., Thistlethwaite, F., Hughes, A. M. & Bradford, J., 20 May 2019, In: Journal of Clinical Oncology. 37, 15_suppl, p. e18063-e18063

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Early Phase 100%
  • Malignant Neoplasm 100%
  • Patient Data 100%
  • Patient Coding 50%
  • Conference Room 50%

• A multidisciplinary-tailored digital solution to data capture in early phase clinical trials.

  Graham, D. M., Wickert, G., Goodwin, L., Clarke, J., Timmins, C., Chang, D., Walker, A., Rees, A., Stringer, S., Theis, A., Carter, L., Cook, N., Krebs, M., Thistlethwaite, F. C., Bradford, J., Royle, J. & Hughes, A. M., 7 Oct 2019, In: Journal of Global Oncology. 5, suppl, p. 2-2 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Simulated Patient 100%
  • Acceptance Test 100%
  • Early Phase 100%
  • Malignant Neoplasm 100%
  • Patient Data 100%

• EVALUATION OF OLDER PATIENTS IN EARLY PHASE CLINICAL TRIALS

  Lowe, J., Lauste, R., Descamps, T., Krebs, M., Graham, D., Thistlethwaite, F., Carter, L. & Cook, N., Nov 2019, In: Journal of Geriatric Oncology. 10, 6, p. S109

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Meeting Proceedings of the “Phase I: Where Science Becomes Medicine” Conference, Manchester, UK

  Graham, D., Carter, L., Krebs, M., Jodrell, D. I., Armstrong, A., Kilgour, E., Illidge, T., Mowll-Clarke, J., Chown, R., Williams, K., Dive, C., Yorke, J., Dickinson, C., Hughes, A., Thistlethwaite, F., Bristow, R. & Cook, N., 2019, In: Journal of Immunotherapy and Precision Oncology. 2, 4, p. 156-174 19 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2018

  Antibiotic use and efficacy of small molecule inhibitors in patients with advanced cancer

  Tan, G., Tinsley, N., Zhou, C., Villa, S., Lorigan, P., Blackhall, F., Krebs, M., Carter, L., Thistlethwaite, F., Hughes, A. & Cook, N., 8 Nov 2018, In: British Journal of Cancer. 119, 11, p. 25-25

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2017

  Dose-exposure-response relationship between AZD6738 and peripheral monocytes.

  Pierce, A., Berges, A., Cheung, S. Y. A., Standifer, N., Ross, G., Smith, S., Hollingsworth, S. J., Krebs, M., Postel-Vinay, S., Bang, Y.-J., El-Khoueiry, A. B., Abida, W., Sundar, R., Carter, L., Castanon-Alvarez, E., Im, S.-A., Lopez, J. S., Yap, T. A., Harrington, K. & Soria, J.-C., 20 May 2017, In: Journal of Clinical Oncology. 35

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2014

  Circulating tumor cells from small cell lung cancer patients are tumorigenic

  Morrow, C. J., Hodgkinson, C. L., Li, Y., Metcalf, R., Rothwell, D., Trapani, F., Polanski, R., Burt, D., Simpson, K., Morris, K., Pepper, S., Nonaka, D., Greystole, A., Kelly, P., Krebs, M., Antonello, J., Ayub, M., Faulkner, S., Priest, L. & Carter, L. & 5 others, Tate, C., Miller, C. J., Blackhall, F., Brady, G. & Dive, C., 1 Oct 2014, In: Cancer Research. 74, 19

  Research output: Contribution to journal › Meeting Abstract › peer-review