Maciej Tomaszewski

Maciej Tomaszewski

Prof

  • Division of Cardiovascular Sciences
    Faculty of Biology Medicine & Health
    Room 5.014, 5th Floor AV Hill Building
    University of Manchester
    Oxford Road
    Manchester
    M13 9PT

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Overview

Biography

Professor Maciej Tomaszewski is a clinician-scientist interested in cardiovascular and renal disease, in particular – hypertension.

After completion of his MD, he was awarded a junior International Society of Hypertension clinical research fellowship (at the University of Glasgow) and subsequently career development awards from the Wellcome Trust, Scottish Chief Scientist Office and USA National Institute of Health (NIH). In 2006 he was appointed to a competitive New Blood Lectureship at the University of Leicester. Between 2009 and 2015 he was a senior clinical lecturer at the Department of Cardiovascular Sciences in Leicester. In 2015 he was awarded Chair of Cardiovascular Medicine in the Division of Cardiovascular Sciences, University of Manchester, and an honorary consultant physician position at the Manchester University NHS Foundation Trust. He is a co-lead for Integrative Cardiovascular Medicine Theme of NIHR Manchester Biomedical Research Centre.

Professor Tomaszewski is known for his international leadership in hypertension. He is a member of the Scientific Council of International Society of Hypertension (ISH). Between 2016 and 2018 he served as ISH Secretary and between 2020 and 2022 he was President of the Society and chairman of both its Scientific Council and the Executive Committee. He has been on Editorial Boards of leading hypertension journals including Hypertension, Journal of Hypertension, Journal of Human Hypertension and Blood Pressure. He chaired the Board of Management of Journal of Hypertension (2019-2022) and currently co-chairs European Society of Hypertension-International Society of Hypertension Journal of Hypertension Committee. He is an associate editor for Cardiovascular Research and an international consulting editor for Hypertension Research. He is also Fellow of the American Heart Association, International Society of Hypertension and Royal College of Physicians (London). He played an active part on the Programme Committees of several international meetings organised by International and European Society of Hypertension and served on management of hypertension guidelines taskforces/committees. He received several academic accolades including awards from European Society of Hypertension, International Society of Hypertension, American Heart Association and European Atherosclerosis Society.

His basic research focuses on genetic mechanisms of cardiovascular and renal diseases. He established one the largest collections of human kidney tissue characterised at genome-, transcriptome-, and epigenome-wide levels to facilitate translation of findings from genome-wide association studies into specific genes, molecules and pathways underpinning the genetic associations with blood pressure, chronic kidney disease and other complex polygenic traits. The insights delivered from Human Kidney Tissue Resource-based projects have been published in top journals including Nature Genetics, European Heart Journal, Nature Communications, Kidney International, Journal of the American Society of Nephrology, etc.

Professor Tomaszewski’s clinical research focuses on management of difficult to treat hypertension. He led the implementation of high performance liquid chromatography-based urine analysis as a direct, non-invasive and objective screening tool for non-adherence to antihypertensive treatment. He has been driving the integration of the biochemical screening for non-adherence to blood pressure lowering therapy into the routine diagnostic strategy to resistant hypertension locally, nationally and internationally through his contributions to Global Hypertension Practice Guidelines and European Society of Hypertension Working Group on Cardiovascular Pharmacotherapy and Adherence (of which he was a founding member). He is a chief investigator and chair of the Trial Management Committee of the British Heart Foundation-funded multi-centre BiOmarkers in Urine, anTihypeRtensive trEAtment and blood pressure Control in Hypertensive patients (OUTREACH) study.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension

    Charchar, F. J., Prestes, P. R., Mills, C., Ching, S. M., Neupane, D., Marques, F. Z., Sharman, J. E., Vogt, L., Burrell, L. M., Korostovtseva, L., Zec, M., Patil, M., Schultz, M. G., Wallen, M. P., Renna, N. F., Islam, S. M. S., Hiremath, S., Gyeltshen, T., Chia, Y-C., Gupta, A., & 26 othersSchutte, A. E., Klein, B., Borghi, C., Browning, C. J., Czesnikiewicz-Guzik, M., Lee, H-Y., Itoh, H., Miura, K., Brunström, M., Campbell, N. R. C., Akinnibossun, O. A., Veerabhadrappa, P., Wainford, R. D., Kruger, R., Thomas, S. A., Komori, T., Ralapanawa, U., Cornelissen, V. A., Kapil, V., Li, Y., Zhang, Y., Jafar, T. H., Khan, N., Williams, B., Stergiou, G. & Tomaszewski, M., 1 Jan 2024, In: Journal of hypertension. 42, 1, p. 23-49 27 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action

    Campbell, N. R. C., Whelton, P. K., Orias, M., Wainford, R. D., Cappuccio, F. P., Ide, N., Neal, B., Cohn, J., Cobb, L. K., Webster, J., Trieu, K., He, F. J., McLean, R. M., Blanco-Metzler, A., Woodward, M., Khan, N., Kokubo, Y., Nederveen, L., Arcand, J., MacGregor, G. A., & 65 othersOwolabi, M. O., Lisheng, L., Parati, G., Lackland, D. T., Charchar, F. J., Williams, B., Tomaszewski, M., Romero, C. A., Champagne, B., L'Abbe, M. R., Weber, M. A., Schlaich, M. P., Fogo, A., Feigin, V. L., Akinyemi, R., Inserra, F., Menon, B., Simas, M., Neves, M. F., Hristova, K., Pullen, C., Pandeya, S., Ge, J., Jalil, J. E., Wang, J-G., Wideimsky, J., Kreutz, R., Wenzel, U., Stowasser, M., Arango, M., Protogerou, A., Gkaliagkousi, E., Fuchs, F. D., Patil, M., Chan, A. W-K., Nemcsik, J., Tsuyuki, R. T., Narasingan, S. N., Sarrafzadegan, N., Ramos, M. E., Yeo, N., Rakugi, H., Ramirez, A. J., Álvarez, G., Berbari, A., Kim, C-I., Ihm, S-H., Chia, Y-C., Unurjargal, T., Park, H. K., Wahab, K., McGuire, H., Dashdorj, N. J., Ishaq, M., Ona, D. I. D., Mercado-Asis, L. B., Prejbisz, A., Leenaerts, M., Simão, C., Pinto, F., Almustafa, B. A., Spaak, J., Farsky, S., Lovic, D. & Zhang, X-H., Jun 2023, In: Journal of Human Hypertension. 37, 6, p. 428-437 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA)

    Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., Azizi, M., Benetos, A., Borghi, C., Hitij, J. B., Cifkova, R., Coca, A., Cornelissen, V., Cruickshank, J. K., Cunha, P. G., Danser, A. H. J., & 39 othersPinho, R. M. D., Delles, C., Dominiczak, A. F., Dorobantu, M., Doumas, M., Fernández-Alfonso, M. S., Halimi, J-M., Járai, Z., Jelaković, B., Jordan, J., Kuznetsova, T., Laurent, S., Lovic, D., Lurbe, E., Mahfoud, F., Manolis, A., Miglinas, M., Narkiewicz, K., Niiranen, T., Palatini, P., Parati, G., Pathak, A., Persu, A., Polonia, J., Redon, J., Sarafidis, P., Schmieder, R., Spronck, B., Stabouli, S., Stergiou, G., Taddei, S., Thomopoulos, C., Tomaszewski, M., Van de Borne, P., Wanner, C., Weber, T., Williams, B., Zhang, Z-Y. & Kjeldsen, S. E., 1 Dec 2023, In: Journal of hypertension. 41, 12, p. 1874-2071 198 p.

    Research output: Contribution to journalEditorialpeer-review

  • Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension

    Schutte, A. E., Jafar, T. H., Poulter, N. R., Damasceno, A., Khan, N. A., Nilsson, P. M., Alsaid, J., Neupane, D., Kario, K., Beheiry, H., Brouwers, S., Burger, D., Charchar, F. J., Cho, M-C., Guzik, T. J., Haji Al-Saedi, G. F., Ishaq, M., Itoh, H., Jones, E. S. W., Khan, T., & 19 othersKokubo, Y., Kotruchin, P., Muxfeldt, E., Odili, A., Patil, M., Ralapanawa, U., Romero, C. A., Schlaich, M. P., Shehab, A., Mooi, C. S., Steckelings, U. M., Stergiou, G., Touyz, R. M., Unger, T., Wainford, R. D., Wang, J-G., Williams, B., Wynne, B. M. & Tomaszewski, M., 1 Feb 2023, In: Cardiovascular research. 119, 2, p. 381-409 29 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

    Siedlinski, M., Carnevale, L., Xu, X., Carnevale, D., Evangelou, E., Caulfield, M. J., Maffia, P., Wardlaw, J., Samani, N. J., Tomaszewski, M., Lembo, G., Holmes, M. V. & Guzik, T. J., 14 Jun 2023, In: European Heart Journal . 44, 23, p. 2114-2125 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access