Mahetab Amer

Mahetab Amer

Dr

 https://orcid.org/0000-0002-1493-3181

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PhD projects

Dr Amer leads an interdisciplinary research programme at the interface of regenerative medicine and biomaterials, investigating how the 3D microenvironment regulate cell fate, osteoimmunology, and tumour–bone interactions. Projects may address bone disease (e.g. osteoarthritis and osteoporosis), bone cancers, and cancer metastasis to bone, combining micro-engineered materials, cell biology, -omics, and/or advanced imaging to address fundamental mechanisms of skeletal regeneration and disease.

Personal profile

Overview

Areas of expertise: Cell-matrix interactions; Tissue engineering; Mesenchymal stem cells; 3D models of health and disease; Cell therapies; Regenerative Medicine
 
Recent developments in biomaterials engineering have opened up exciting new avenues in regenerative medicine. Biomaterials can be engineered as artificial niches for stem cells in order to advance our understanding of their biology under biomimetic three-dimensional settings, as well as for developing novel strategies for the directed differentiation of stem cells in regenerative medicine and cell therapies.
 

Biography

Mahetab was awarded a BSc in Pharmacy and a MSc in Pharmaceutical Sciences before completing her PhD in Tissue Engineering and Regenerative Medicine at the University of Nottingham (2017), for which she received the prestigious Andrew Hendry Endowed Postgraduate Award. She then spent three years as a Postdoctoral Research Fellow as part of the EPSRC-funded 'Next Generation Biomaterials Discovery' programme grant, where she was involved in several multidisciplinary research projects spanning biomaterials research, cell biology, regenerative medicine, chemistry and additive manufacturing. Mahetab has received several awards for her research, including the Robert Brown Early Investigator Award by the Tissue and Cell Engineering Society in 2018. She is currently a member of the Editorial (ECR) Board of Materials Today Bio, and has been an external reviewer and/or panel member for UKRI, the Academy of Medical Sciences and Swiss National Science Foundation. Mahetab was awarded a University Academic Fellowship at the University of Leeds in 2020. She joined the Division of Cell Matrix Biology and Regenerative Medicine at the University of Manchester as a Lecturer of Regenerative Medicine in 2023.
 

Research interests

Our research interests focus on exploring (stem) cell-material interactions, and how these can be exploited to recreate original functionality for artificial stem cell niche engineering, designing novel regenerative therapies, and developing in vitro models.

Current research in my laboratory focuses on utilising multidisciplinary tissue engineering approaches to develop next-generation regenerative therapies and in vitro models of healthy and diseased tissues, with a focus on recreating and studying the matrix-mediated mechanisms underlying disorders of the bone, bone marrow, and mesenchymal stem cell-associated diseases, with the potential for future translation for use in personalised medicine and high-throughput drug screening platforms.

Postgraduate research opportunities

We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. We have PhD projects advertised on findaphd.com. 

Qualifications

  • PhD; Tissue Engineering and Cell Therapies
  • Fellowship of the Higher Education Academy
  • PG Dipl.; Total Quality Management
  • MSc; Pharmaceutical Sciences
  • BSc; Pharmacy

Memberships of committees and professional bodies

  • UK Tissue and Cell Engineering Society (Elected member of the Executive Board)
  • Tissue Engineering and Regenerative Medicine International Society
  • UKRI Interdisciplinary Assessment College

Research Beacons, Institutes and Platforms

  • Christabel Pankhurst Institute
  • Advanced materials
  • Cancer
  • Biotechnology

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • 24 Article
  • 1 Conference contribution
  • 1 Review article
  • 1 Preprint
View all 27 research outputs