Personal profile


Professor of Cardiovascular Medicine, The University of Manchester

Professor and Chair of Pharmacology, Professor of Molecular Physiology and Biophysics, University of Vermont, Link to Homepage

Visiting Professor, Department of Oxford

Google Scholar Citation Index

Memberships of committees and professional bodies

  • National Academy of Sciences (USA)
  • Vermont Academy of Arts and Science
  • Vermont Academy of Science and Engineering
  • American Physiological Society
  • American Society for Biochemistry and Molecular Biology (ASBMB)
  • American Society for Pharmacology & Experimental Therapeutics (ASPET)
  • Biophysical Society
  • Council on Basic Sciences, American Heart Association
  • Society of General Physiologists
  • Society for Neuroscience
  • Associate of Medical School Pharmacology

Research interests

Membrane transport and ion channels. In particular, to apply molecular, physiological, biophysical and pharmacological approaches to understand the roles of ion channels and calcium signaling in the function and dysfunction of smooth muscle, with an emphasis on urinary bladder and neurovascular coupling.

Link to Google Scholar Citation Index

Methodological knowledge

Electrophysiology (patch clamp/bilayer/microelectrode techniques)

  • In vitro contraction and pressurized artery measurements
  • High-speed confocal calcium imaging
  • Fluorescence microscopy
  • Transport measurements with radioisotope tracers
  • Immunohisto- and cytochemistry
  • In vivo urodynamic, blood pressure and local cerebral blood flow measurements in mice
  • State-of-the-art PCR techniques (standard PCR, RT-PCR, etc.)
  • Southern and Western blot


  • Toxicology Pharm 272 (Spring 2007 - 2015)
    Lectures on Animal Toxins: Reptiles. Approximately 30 undergraduate and graduate students. Lecture: 1.5 hours/year.
  • Medicinal Chemistry Pharm 328 (Spring 2007 - 2013) Lectures on calcium channel inhibitors, approximately 10 undergraduate and graduate students. Lecture 2 hours/year.
  • Molecular and Cellular Pharmacology Pharm 290 (Spring 2007 - 2010) Lecture on ryanodine receptors, 2 hours/year.
  • Cardiovascular Physiology (Fall 2006 - 2010)
    Lectures on cardiovascular system function, disease, and pharmacological intervention. Topics include membrane structure and function, receptor/drug interactions, excitable membranes, muscle contraction, control by the autonomic and somatic nervous systems, cardiac cycle, and mechanics of vascular blood flow. Approximately 14 graduate students. Lecture: 10 hours/year.
  • Introductory to Pharmacology 201 (Fall 2007 - 2011)
    Lectures on hyperlipidemia, gonadal hormones, thyroid, bone pharmacology, vitamins, adrenal hormones, diabetes. Approximately 14 undergraduate students. Lecture: 6 hours/year.
  • Graduate Course in Neurochemistry (Fall 2005 - 2008)
    Lecture and Discussion Group: calcium as an intracellular messenger. 4 hour/semester.
  • College of Medicine Vermont Integrated Curriculum (Generations and NMGI) (2004-present)
    Lectures on hyperlipidemia, diabetes, adrenal and thyroid. 20 hours/year.
  • Medical Pharmacology 301 (Summer) (1986-2018)
    Lectures on hyperlipidemia, gonadal hormones, thyroid, bone pharmacology, vitamins, adrenal hormones, diabetes. Approximately 35 medical students. Lecture and Conference: 12 hours/year.
  • Pharmacology for Physical Therapists, Pharmacology 190 (1986-2000)
    Spring lectures (5) on Hyperlipidemia, Steroids, and Cardiovascular drugs. Approximately 60 undergraduate students. Lecture 9 hours/ year.
  • Graduate Course in Molecular and Cellular Pharmacology, Pharmacology 290 (1995-2010) Lectures on ion channel and ion pump pharmacology and biophysics. Approximately 15 graduate students. Lecture 6 hours/year.
  • Graduate Course in Molecular and Cell Biology (1986-1998)
    Lectures on ion channels. 2 lectures (4 hours) per year to approximately 30 graduate students


6/96- Chair, Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT
7/95-5/96 Interim Chair, Department of Pharmacology, University of Vermont
5/93- Professor, Department of Molecular Physiology & Biophysics, University of Vermont (Secondary)
7/92- Professor, Department of Pharmacology, College of Medicine, University of Vermont
7/90-6/92 Associate Professor with Tenure, Department of Pharmacology, University of Vermont
6/86-6/90 Assistant Professor, Department of Pharmacology, University of Vermont
9/84-5/86 Assistant Professor, Department of Pharmacology, University of Miami School of Medicine, Miami, FL
11/82-8/84 Research Assistant Professor, Department of Physiology, University of Maryland School of Medicine, Baltimore, MD. Sponsor: Professor B.K. Krueger
6/81-10/82 Research Fellow of the Alexander von Humboldt Stiftung, Fakultät für Biologie, Universität Konstanz, West Germany. Sponsor: Professor P. Läuger
4/80-5/81 Research Fellow of the American Heart Association, Dept. of Physiology, University of Maryland, Baltimore, MD. Sponsor: Professor M.P. Blaustein


1980 Ph.D., Neural Sciences Washington University, St. Louis, MO Advisor: Prof. M.P. Blaustein
1976 B.A., Mathematics & Biology with Honors Tufts University, Medford, MA
1973 Undergraduate studies Swarthmore College, Swarthmore, PA

My collaborations

Adam Greenstein, British Heart Foundation Intermediate Clinical Research Fellow, Institute of Cardiovascular Sciences, University of Manchester

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 17 - Partnerships for the Goals

Areas of expertise

  • QP Physiology
  • Vascular biology
  • ion channels

Research Beacons, Institutes and Platforms

  • Dementia@Manchester


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Collaborations and top research areas from the last five years

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