Research output per year
Research output per year
Personal profile
Overview
Early phase clinical trials (e.g. first-in-human drugs or novel combinations of targeted/immuno-oncology therapies) with a focus in drug development for lung cancer
Precision medicine lead in Experimental Cancer Medicine Team, The Christie NHS Foundation Trust.
Translational circulating biomarker research
Personalised medicine with hypothesis-driven early phase clinical trials in biomarker-enriched populations
Qualifications
Fellow of Royal College of Physicians (London), UK, 2019
PhD in Experimental Pharmacology and Circulating Biomarkers, University of Manchester 2011
Member of Royal College of Physicians (London), UK, 2005
Bachelor of Medicine and Bachelor of Surgery (MB ChB), University of Leicester, 2001
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Manchester Cancer Research Centre
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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110P Real-world experience of molecular tumour boards for clinical decision-making for cancer patients
Colomina, J. H., Johnston, E., Duffus, K., Thistlethwaite, F., Krebs, M. G., Carter, L., Graham, D. & Cook, N., 1 Mar 2025, Abstract book of the ESMO Targeted Anticancer Therapies Congress 2025 3-5 March 2025, Paris, France. Supplement 2 ed. ESMO Press, Vol. 10. (ESMO Open).Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review
Open Access -
Amivantamab in Participants With Advanced NSCLC and MET Exon 14 Skipping Mutations: Final Results From the CHRYSALIS Study
Krebs, M. G., Cho, B. C., Hiret, S., Han, J.-Y., Lee, K. H., Pérez, C. L., De Braud, F., Haura, E. B., Sanborn, R. E., Chih-Hsin Yang, J., Shu, C. A., Goto, K., Nishio, M., Zhao, J., Wang, Z., Tomasini, P., Felip, E., Goldman, J. W., Ignatius Ou, S.-H. & Boyer, M. & 12 others, , Sept 2025, In: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 20, 9, p. 1289-1301 13 p.Research output: Contribution to journal › Article › peer-review
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A Response to the Letter to the Editor: "Durable Benefit Beyond Response: Reinterpreting Amivantamab Efficacy in METex14 NSCLC Subgroups"
Krebs, M. G., Cho, B. C., Kim, P., Spira, A. I. & Leighl, N. B., Oct 2025, In: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 20, 10, p. e109-e110Research output: Contribution to journal › Article › peer-review
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A single centre experience of patients with Rare Cancers referred for Early Phase Clinical Trials
Angelakas, A., Cook, N., Graham, D. A., Krebs, M., Thistlethwaite, F. & Carter, L., 28 Mar 2025, In: BMC Cancer.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating Tumor DNA as a Prognostic Biomarker for Selecting Participants to Early Phase Clinical Trials
Shaya, S., Uche-Ikonne, O., Kilerci, B., Stevenson, J., Greystoke, A., Cook, N., Thistlethwaite, F. C., Carter, L., Graham, D. M. & Krebs, M. G., 1 Aug 2025, In: Journal of Immunotherapy and Precision Oncology. 8, 3, p. 222-232 11 p.Research output: Contribution to journal › Article › peer-review
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NIHR Manchester Biomedical Research Centre
Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Crosbie, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)
1/12/22 → 30/11/27
Project: Research
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NIHR Biomedical Research Centre: Cancer Precision Medicine Theme.
Dive, C. (PI), Baena Chaparro, E. (CoI), Blackhall, F. (CoI), Bruce, I. (CoI), Bundred, N. (CoI), Carter, L. (CoI), Clarke, R. (CoI), Cook, N. (CoI), Crosbie, P. (CoI), Evans, D. (CoI), Harris, J. (CoI), Hawkins, R. (CoI), Hussell, T. (CoI), Illidge, T. (CoI), Jayson, G. (CoI), Jorgensen, C. (CoI), Kirwan, C. (CoI), Kostarelos, K. (CoI), Krebs, M. (CoI), Lorigan, P. (CoI), Marais, R. (CoI), Marshall, K. (CoI), Metcalf, R. (CoI), Payne, K. (CoI), Radford, J. (CoI), Somervaille, T. (CoI), Springer, C. (CoI), Taylor, S. (CoI), Thistlethwaite, F. (CoI), Viros Usandizaga, A. (CoI) & Zelenay, S. (CoI)
1/04/17 → 31/03/19
Project: Research
Prizes
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Bionow Healthcare Project of the Year
Krebs, M. (Recipient), Mar 2023
Prize: Prize (including medals and awards)
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Healthcare Project of The Year
Krebs, M. (Recipient), 24 Mar 2023
Prize: Prize (including medals and awards)
Press/Media
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Patients with rare cancers given hope by UK-led ‘drug-match’ trial 'DETERMINE'
14/10/23 → 15/10/23
2 items of Media coverage
Press/Media: Research
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Phase I trial of divarasib show positive results for patients with Kras-mutated solid tumours
24/08/23 → 5/09/23
3 items of Media coverage
Press/Media: Research
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University joins European precision cancer medicine trial consortium
27/06/23
1 Media contribution
Press/Media: Research
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Precision medicine trial opens for rare adult and paediatric cancers
23/11/22
1 item of Media coverage
Press/Media: Research
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VARIOUS MEDIA: Clinical trials cancer patient hails drug
28/03/22
2 items of Media coverage
Press/Media: Research
Thesis
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The Detection and Clinical Utility of Circulating Tumour Cells in Patients with Non-Small-Cell Lung Cancer and Colorectal Cancer
Krebs, M. (Author), Dive, C. (Supervisor), 11 Oct 2011Student thesis: Phd
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