Maya Buch

Maya Buch

Prof, Honorary Consultant Rheumatologist, PhD FRCP

Personal profile


I am a Professor of Rheumatology and Director of Experimental Medicine at the Centre for Musculoskeletal Research, University of Manchester. I am a NIHR Senior Investigator and at the NIHR Manchester Biomedical Research Centre, lead the ‘Disease complexity and multimorbidity’ cluster and within this, theme lead for ‘Next Generation Therapeutics’. 

My clinical and experimental research programme comprises the following research themes: (i) PRECISion medicinE across the disease continuum to prevent and treat Rheumatoid Arthritis (PRECISE-RA); with a focus on personalised therapeutics in early RA and Difficult-to-Treat-Refractory disease (ii) CARDIOvascular pathology in Immune-Mediated Inflammatory Diseases (CARDIO-IMID) to identify patients at risk of CVD, optimal detection methods and shared mechanisms of CV-IMID comorbidity (iii) Improving therapeutics and cardiovascular outcomes in Systemic Sclerosis. In addition to clinical trials, I undertake complex observational studies and linked experimental investigation to identify prognostic, mechanistic and predictive biomarkers. 

I am Chair of the NIHR-Versus Arthritis UK Musculoskeletal Translational Research Collaboration, which aims to support and innovate the experimental research landscape and deliver meaningful, multi-centre trials in the UK. I lead the Medical Research Council (MRC)-British Heart Foundation (BHF) UK CARDIO(vascular)-IMID (immune mediated inflammatory diseases partnership, bringing together 29 centres to deliver experimental studies in IMID-CVD and I am national lead of NIHR Bioresource rare disease ‘systemic sclerosis’. I have also informed multiple national/European guidelines in RA and SSc.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being

External positions

National lead, Medical Research Council (MRC)

Jun 2023 → …

Chair , NIHR-Versus Arthritis UK Musculoskeletal Translational Research Collaboration

2020 → …

Visiting Professor of Rheumatology, University of Leeds

1 Oct 2019 → …

Co-lead Cardio-Immune work stream, NIHR-BHF Cardiovascular partnership

2019 → …

NIHR Bioresource Systemic Sclerosis national lead

2018 → …

Areas of expertise

  • RZ Other systems of medicine
  • Rheumatology
  • Scleroderma
  • Immune mediated inflammatory disease
  • Cardiovascular
  • RM Therapeutics. Pharmacology
  • Targeted therapies
  • Precision Medicine


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Collaborations and top research areas from the last five years

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