Michael Grant

Search results

• 2003

  Apoptosis of terminal hypertrophic chondrocytes in an in vitro model of endochondral ossification

  Cheung, J. O. P., Grant, M. E., Jones, C. J. P., Hoyland, J. A., Freemont, A. J. & Hillarby, M. C., Nov 2003, In: Journal of Pathology. 201, 3, p. 496-503 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chondrocyte 100%
  • Culture 88%
  • Programmed Cell Death 66%
  • Apoptosis 66%
  • Azacitidine 44%
• 2001

  Coordinated expression of matrix Gla protein is required during endochondral ossification for chondrocyte survival

  Newman, B., Gigout, L. I., Sudre, L., Grant, M. E. & Wallis, G. A., 6 Aug 2001, In: Journal of Cell Biology. 154, 3, p. 659-666 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteocalcin 100%
  • Matrix Gla Protein 92%
  • Chondrocyte 69%
  • Mineralization 23%
  • Therapeutic Procedure 15%
• 2000

  Role of pericytes in vascular caclification: a review

  Canfield, AE., Doherty, MM. J., Wood, AA. C., Farrington, CC., Begum, N., Harvey, B., Poole, A., Grant, MM. E. & Boot-Handford, RR., 2000, In: Zeitschrift fuer Kardiologie. 89.2

  Research output: Contribution to journal › Article › peer-review
• 1999

  Identification and functional analysis of genes involved in the osteogenic differentiation of pericytes

  Canfield, AE., Wood, AC., Doherty, MJ., Grant, MM. E. & Boot-Handford, RR., 1999, In: Journal of Bone Mineral Research. 14

  Research output: Contribution to journal › Article › peer-review
• 1998

  Identification of genes expressed during the osteogenic differentiation of vascular pericytes in vitro

  Doherty, M., Boot-Handford, R. P., Grant, M. E. & Canfield, A. E., 1998, In: Biochemical Society Transactions. 26, 1, p. S4

  Research output: Contribution to journal › Article › peer-review

• The bcl-2 knockout mouse exhibits marked changes in osteoblast phenotype and collagen deposition in bone as well as a mild growth plate phenotype

  Boot-Handford, R. P., Michaelidis, T. M., Hillarby, M. C., Zambelli, A., Denton, J., Hoyland, J. A., Freemont, A. J., Grant, M. E. & Wallis, G. A., 1998, In: International Journal of Experimental Pathology. 79, 5, p. 329-335 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteoblast 100%
  • Bone 83%
  • Phenotype 66%
  • Epiphyseal Plate 50%
  • Age 33%

• Vascular pericytes express osteogenic potential in vitro and in vivo

  Doherty, M. J., Ashton, B. A., Walsh, S., Beresford, J. N., Grant, M. E. & Canfield, A. E., May 1998, In: Journal of Bone and Mineral Research. 13, 5, p. 828-838 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pericyte 100%
  • Cells 66%
  • Marker 33%
  • Osteoblast 33%
  • Adipocyte 33%
• 1996

  Expression of osteogenic markers by vascular pericytes

  Doherty, MJ., Ashton, BA., Grant, MM. E. & Canfield, AE., 1996, In: Journal of Bone Mineral Research. 11

  Research output: Contribution to journal › Article › peer-review

• Localisation of gene expression during endochondral ossification

  Hillarby, M., King, K., Brady, G., Grant, MM. E., Wallis, GA. & Boot-Handford, RR., 1996, In: Annals of the New York Academy of Science. 785

  Research output: Contribution to journal › Article › peer-review

• Vascular pericytes express osteogenic markers in vitro and form bone in vivo

  Doherty, MJ., Ashton, BA., Grant, MM. E. & Canfield, AE., 1996, In: International Journal of Experimental Pathology. 77

  Research output: Contribution to journal › Article › peer-review
• 1995

  Vascular pericytes as possible osteoprogenitor cells

  Doherty, MJ., Ashton, BA., Grant, MM. E. & Canfield, AE., 1995, In: Bone. 17

  Research output: Contribution to journal › Article › peer-review
• 1992

  Aortic endothelial cell heterogeneity in vitro: Lack of association between morphological phenotype and collagen biosynthesis

  Canfield, A. E., Wren, F. E., Schor, S. L., Grant, M. E. & Schor, A. M., Aug 1992, In: Journal of Cell Science. 102, 4, p. 807-814 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells 100%
  • Cell Line 75%
  • Phenotype 75%
  • Endothelial Cells 62%
  • Collagen 37%
• 1990

  Modulation of extracellular matrix biosynthesis by bovine retinal pericytes in vitro: Effects of the substratum and cell density

  Canfield, A. E., Allen, T. D., Grant, M. E., Schor, S. L. & Schor, A. M., May 1990, In: Journal of Cell Science. 96, 1, p. 159-169 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix 100%
  • Collagen Gel 80%
  • Contrast 40%
  • Phenotype 40%
  • Protein 20%
• 1989

  Plasminogen activator inhibitor-type I is a major biosynthetic product of retinal microvascular endothelial cells and pericytes in culture

  Canfield, A. E., Schor, A. M., Loskutoff, D. J., Schor, S. L. & Grant, M. E., 1989, In: Biochemical Journal. 259, 2, p. 529-535 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelial Cell 100%
  • Pericyte 100%
  • Plasminogen Activator Inhibitor-1 80%
  • Species 40%
  • Protein 40%
• 1987

  Identification and partial characterisation of two major proteins of Mr47000 synthesised by bovine retinal endothelial cells in culture

  Canfield, AE., Schor, AM., West, DC., Schor, SL. & Grant, MM. E., 1987, In: Biochemical Journal. 246

  Research output: Contribution to journal › Article › peer-review
• 1986

  The biosynthesis of extracellular-matrix components by bovine retinal endothelial cells displaying distinctive morphological phenotypes

  Canfield, A. E., Schor, A. M., Schor, S. L. & Grant, M. E., 1986, In: Biochemical Journal. 235, 2, p. 375-383 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells 100%
  • Endothelial Cell 50%
  • Morphology 40%
  • Procollagen 40%
  • Synthesis 30%