Research output per year
Research output per year
Personal profile
Overview
Dr Cook’s research focuses on development of early phase clinical trials of experimental anti-cancer therapies, translational assay development and early phase trials for gastrointestinal cancers
Biography
Dr Cook attended medical school at the University of Sheffield, gained MRCP and was accepted into the specialist training program in Medical Oncology at Cambridge University Teaching Hospitals Trust. She completed a PhD at the University of Cambridge. This was funded by a CRUK Clinical Training fellowship and investigated the role of the Notch pathway in pancreatic cancer. In 2012 she was awarded the Rothwell Jackson Postgraduate Travelling Fellowship and travelled to Canada to undertake a 2 year drug development research fellowship, based at the University of Toronto and Princess Margaret Cancer Centre. She is now based at the Clinical Trials Unit, Oak Road Treatment Centre and will be working with the Experimental Cancer Medicine Team delivering early phase trials to patients, whilst developing her research interests in translational assay design and gastrointestinal oncology.
Teaching
She is interested in teaching and supervision of undergraduate and postgraduate students in health-related specialities
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Cancer
- Manchester Cancer Research Centre
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A single centre experience of patients with Rare Cancers referred for Early Phase Clinical Trials
Angelakas, A., Cook, N., Graham, D. A., Krebs, M., Thistlethwaite, F. & Carter, L., 13 Mar 2025, (Accepted/In press) In: BMC Cancer.Research output: Contribution to journal › Article › peer-review
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A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary
Conway, A.-M., Pearce, S. P., Clipson, A., Hill, S., Chemi, F., Slane-Tan, D., Ferdous, S., Hossain, A. S. M. M., Kamieniecka, K., White, D. J., Mitchell, C., Kerr, A., Krebs, M. G., Brady, G., Dive, C., Cook, N. & Rothwell, D., 17 Apr 2024, In: Nature Communications. 15, 1, 3292.Research output: Contribution to journal › Article › peer-review
Open Access -
Amplifying the Patient's Voice in Oncology Early-Phase Clinical Trials: Solutions to Burdens and Barriers
Spencer, K., Butenschoen, H., Alger, E., Bachini, M. & Cook, N., 1 Jun 2024, In: American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting. 44, 3, p. e433648Research output: Contribution to journal › Review article › peer-review
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A Phase I trial of AVA6000, a Fibroblast Activation Protein (FAP)-released and tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors
Banerji, U., Cook, N., Anthoney, A., Plummer, R., Tap, W. D., Evans, J. T., Cranmer, L. D., Plummer, C., Loadman, P., Lahu, G., Jones, H. S., Kinnersley, N., McLaughlin, F. & Twelves, C., 1 Apr 2024, In: Cancer Research. 84, 7 Supplement, 2 p., CT188.Research output: Contribution to journal › Meeting Abstract › peer-review
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Biomarkers of systemic inflammation provide additional prognostic stratification in cancers of unknown primary
Harvey, S., Stares, M., Scott, J. A., Thottiyil, T. J. V., Conway, A. M., Haigh, R., Brown, J., Knowles, G., Dasgupta, S., Shiu, K. K., Mitchell, C., Barrie, C., Cook, N. & Clive, S., 25 Feb 2024, In: Cancer Medicine. 13, 3, e6988.Research output: Contribution to journal › Article › peer-review
Open Access
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NIHR Manchester Biomedical Research Centre
Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Crosbie, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)
1/12/22 → 30/11/27
Project: Research
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NIHR Biomedical Research Centre: Cancer Precision Medicine Theme.
Dive, C. (PI), Baena Chaparro, E. (CoI), Blackhall, F. (CoI), Bruce, I. (CoI), Bundred, N. (CoI), Carter, L. (CoI), Clarke, R. (CoI), Cook, N. (CoI), Crosbie, P. (CoI), Evans, D. (CoI), Harris, J. (CoI), Hawkins, R. (CoI), Hussell, T. (CoI), Illidge, T. (CoI), Jayson, G. (CoI), Jorgensen, C. (CoI), Kirwan, C. (CoI), Kostarelos, K. (CoI), Krebs, M. (CoI), Lorigan, P. (CoI), Marais, R. (CoI), Marshall, K. (CoI), Metcalf, R. (CoI), Payne, K. (CoI), Radford, J. (CoI), Somervaille, T. (CoI), Springer, C. (CoI), Taylor, S. (CoI), Thistlethwaite, F. (CoI), Viros Usandizaga, A. (CoI) & Zelenay, S. (CoI)
1/04/17 → 31/03/19
Project: Research