Personal profile
Overview
- Professor of Medicine, University of Manchester
- Director of Research & Innovation, Manchester University NHS Foundation Trust
- Honorary Consultant Endocrinologist at Manchester Royal Infirmary
Memberships of committees and professional bodies
- Association of Physicians (President, 2018-2019)
- Society for Endocrinology (Council 2014-2018)
- Endocrine Society
- Fellow of the Royal College of Physicians
Research interests
Neil researches human developmental biology and associated aspects of stem cell biology. For over 20 years, this has focussed on embryogenesis and the early fetal period, with a keen interest in how human organs become established. More widely, he collaborates on organ fibrosis and associated disease processes; work that originated from researching human developmental mechanisms. Please see the Publications section for more details.
As Director of R & I at Manchester University NHS Foundation Trust (MFT), Neil has responsiblility for developing research and innovation at the largest NHS Trust in the country spanning nine hospitals and additional hosted organisations with over 500 staff and an annual budget over £50M. This inclues the Manchester Royal Infirmary, Wythenshawe Hospital, Royal Manchester Children's Hospital, St Mary's (Women's) Hospital, Royal Manchester Eye Hospital and the Manchester Dental Hospital, the interface with primary care for nearly two million people via the Manchester Local Care Organisation, and the Citylabs Innovation Campus.
Teaching
Neil has held multiple roles in academic training. He set up and directs the Faculty's Fellowship Academy with a rolling roster of approximately 100 externally funded fellows (UKRI, NIHR, Wellcome and other charities) and has served terms on MRC and NIHR panels. He co-authored NIHR's 2017 Strategic Review of Training.
He has taught all aspects of undergraduate and postgraduate endocrinology and is author, with Professor Richard Holt (University of Southampton), of 'Essential Endocrinology & Diabetes', a textbook published by Wiley-Blackwell, the latest edition of which has sold over 8,000 copies worldwide.
Biography
Neil Hanley graduated from the University of Edinburgh in 1993 with a MBChB in Medicine and Surgery, and a BSc Hons in Pharmacology. After 'House jobs', he moved to Newcastle to complete early internal medicine postgraduate training and MRCP, after which he began a PhD in Molecular Genetics as a Wellcome Clinical Training Fellow. He spent two years with Dr Keith Parker at UT Southwestern Medical Center at Dallas, USA, as a visiting fellow. He returned to the UK in 2000 to the University of Southampton, completing speciality training in Endocrinology and Diabetes in 2004 while he was an NIHR Clinician Scientist. He was awarded a personal Chair in 2006 and moved to a Chair of Medicine position at the University of Manchester in 2008 as part of Manchester's first NIHR Biomedical Research Centre. During his time in Manchester, he has held a Wellcome Trust Senior Fellowship in Clinical Science alongside research grants from MRC, BBSRC, EPSRC and other bodies, and led the Centre for Endocrinology & Diabetes (2013-2017). In 2018, he served as President of the Association of Physicians of GB & Ireland and helped oversee its transition into an open membership body.
Qualifications
- PhD (University of Newcastle)
- MRCP (Royal College of Physicians; now FRCP)
- MBChB in Medicine and Surgery (University of Edinburgh)
- BSc Hons in Pharmacology (University of Edinburgh)
Research Beacons, Institutes and Platforms
- Christabel Pankhurst Institute
- Creative Manchester
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 10 Reduced Inequalities
Fingerprint
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Collaborations and top research areas from the last five years
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Lessons learned from North West England Research Partnership to Improve Early Detection of Liver Disease
Gahloth, D., Street, O., Landi, S., Mysko, C., Purssell, H., Rogers, G., Payne, K., Hanley, K. P., Hanley, N. & Athwal, V., 12 Jan 2026, In: NIHR Open Research.Research output: Contribution to journal › Article
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EVC protein regulates Sonic hedgehog signaling during human intervertebral disc development and degeneration
Wu, Z., Shaw, L., Dube, C., Ionescu, A.-M., Qiu, T., Tierney, A., Baird, P., Patel, S., Zeef, L., Birchall, L., Jennings, R., Hanley, N., Unwin, R., Hoyland, J. & Richardson, S., 26 Nov 2025, (Accepted/In press) In: iScience.Research output: Contribution to journal › Article › peer-review
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HAND1 level controls the speci fication of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
Lynch, A., Phillips, N., Douglas, M., Dorgnach, M., Lin, I.-H., Adamson, A., Darieva, Z., Whittle, J., Hanley, N., Bobola, N. & Birket, M. (Lead), 2 May 2025, In: EMBO Journal. 44, 9, p. 2541 - 2565Research output: Contribution to journal › Article › peer-review
Open Access -
Health inequalities in hepatocellular carcinoma surveillance, diagnosis, treatment, and survival in the United Kingdom: a scoping review
Mysko, C., Landi, S., Purssell, H., Allen, A. J., Prince, M., Lindsay, G., Rodrigues, S., Irvine, J., Street, O., Gahloth, D., MacLennan, S., Hanley, K. P., Hanley, N. & Athwal, V. S., 3 Mar 2025, In: BJC reports. 3, 13 .Research output: Contribution to journal › Article › peer-review
Open Access -
Metaplastic Barrett's oesophagus represents reversion to a developmental-like epithelial cell state
Murtuza Baker, S., Mullan, A., Jennings, R. E., Piper Hanley, K., Ang, Y., Palles, C., Hanley, N. A. & Sharrocks, A. D., 15 Nov 2025, In: Development (Cambridge, England). 152, 22Research output: Contribution to journal › Article › peer-review
Projects
- 3 Finished
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The UK Interstitial Lung Disease Long-COVID19 study (UKILD-Long COVID): understanding the burden of Interstitial Lung Disease in Long COVID.
Piper Hanley, K. (PI), Blaikley, J. (CoI) & Hanley, N. (CoI)
17/02/21 → 16/08/22
Project: Research
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Integrated Diagnostics for Early Diagnosis of Liver Disease [ID-LIVER}
Hanley, N. (PI), Ainsworth, J. (CoI), Athwal, V. (CoI), Martin, K. (CoI), Payne, K. (CoI), Piper Hanley, K. (CoI) & Rattray, M. (CoI)
1/09/20 → 31/03/24
Project: Research
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PHOSP-COVID: PHOSP-COVID Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes
Horsley, A. (PI), Blaikley, J. (CoI), Buch, M. (CoI), Hanley, N. (CoI) & Piper Hanley, K. (CoI)
30/07/20 → 29/01/22
Project: Research
Datasets
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Human Embryonic Multi-tissue ChIP-seq (Manchester)
Gerrard, D. (Creator), Hanley, N. (Owner) & Jennings, R. (Data Manager), The European Genome-phenome Archive, 2019
https://ega-archive.org/datasets/EGAD00001004335
Dataset
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Processed single cell RNA-seq data for manuscript "HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells"
Birket, M. (Creator), Lynch, A. (Creator), Phillips, N. (Creator), douglas, M. (Creator), Dorgnach, M. (Creator), Lin, I.-H. (Creator), Adamson, A. (Creator), Darieva, Z. (Creator), Whittle, J. (Creator), Hanley, N. (Creator) & Bobola, N. (Creator), University of Manchester Figshare, 10 Mar 2025
DOI: 10.48420/26935324, https://figshare.manchester.ac.uk/articles/dataset/Processed_single_cell_RNA-seq_data_for_manuscript_HAND1_level_controls_the_specification_of_multipotent_cardiac_and_extraembryonic_progenitors_from_human_pluripotent_stem_cells_/26935324/1 and one more link, https://figshare.manchester.ac.uk/articles/dataset/Processed_single_cell_RNA-seq_data_for_manuscript_HAND1_level_controls_the_specification_of_multipotent_cardiac_and_extraembryonic_progenitors_from_human_pluripotent_stem_cells_/26935324 (show fewer)
Dataset
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Dataset EV1 for manuscript "HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells"
Birket, M. (Creator), Lynch, A. (Creator), Phillips, N. (Creator), douglas, M. (Creator), Dorgnach, M. (Creator), Lin, I.-H. (Creator), Adamson, A. (Creator), Darieva, Z. (Creator), Whittle, J. (Creator), Hanley, N. (Creator) & Bobola, N. (Creator), University of Manchester Figshare, 10 Mar 2025
DOI: 10.48420/26364184, https://figshare.manchester.ac.uk/articles/dataset/Dataset_EV1_for_manuscript_HAND1_level_controls_the_specification_of_multipotent_cardiac_and_extraembryonic_progenitors_from_human_pluripotent_stem_cells_/26364184/1
Dataset
Press/Media
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Ground breaking liver disease screening study reaches 2000 patients
Landi, S., Purssell, H., Mysko, C., Street, O., Piper Hanley, K., Athwal, V. & Hanley, N.
2/07/25
1 Media contribution
Press/Media: Research
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New research highlights inequalities in liver cancer care
Mysko, C., Landi, S., Street, O., Gahloth, D., Hanley, N., Piper Hanley, K. & Athwal, V.
11/04/25
1 item of Media coverage
Press/Media: Research
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Life-saving technology in Manchester detects patients in early, curable stages of liver cancer
Mysko, C., Landi, S., Street, O., Hanley, N., Piper Hanley, K. & Athwal, V.
3/04/25
1 item of Media coverage
Press/Media: Research
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The six least survivable cancers – and how to protect yourself against them
Mysko, C., Landi, S., Street, O., Hanley, N., Piper Hanley, K. & Athwal, V.
15/01/25
1 item of Media coverage
Press/Media: Research
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Greater Manchester’s state-of-the-art mobile research clinic rolls into Old Trafford
31/01/23
1 item of Media coverage
Press/Media: Research