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Nicoletta Bobola, Ph.D


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Personal profile


2016-       Professor in Developmental Biology and Genomics

2013- 16  Senior Lecturer, University of Manchester, Manchester, UK

2006-13   Lecturer, University of Manchester, Manchester, UK

2001-06   Junior Group Leader Max-Planck Institute of Immunobiology in Freiburg, Germany

2000-01  Postdoctoral Fellow, Max-Planck Institute of Immunobiology in Freiburg, Germany

Research interests

As human and other animal embryos develop, many different cell types must be generated at the right place and time.  Because all the descendant cells of a unicellular embryo share the same genome, differentiation is achieved when cells use different portions of this common genome and transcribe different genes. Interactions between regulatory elements in the genome and a vast range of transcription factors modulate transcription; these combinatorial interactions are highly dynamic, tissue-specific and time-dependent.  

 My research group uses the latest genomics technologies to study development in human, mouse, chick and fish embryos. We generate and integrate data on chromatin states, occupancy of transcriptional regulators (ChIP-seq) and transcriptional profiles (RNA-seq), to decipher the transcriptional networks that guide apparently similar blocks of tissue into forming anatomical structures such as the face, the ear and the heart.  


1996   PhD, University of  Genoa, Italy and Institute of Molecular Pathology, Vienna, Austria

1989   Degree in Biological Sciences, University of Genoa, Italy

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Beacons, Institutes and Platforms

  • Digital Futures


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