Norman Van Rhijn

Accepting PhD Students

PhD projects

Currently only taking self-funded PhD students

Personal profile

Overview

I am a Wellcome Trust Research Fellow in Microbial Evolution Research Manchster (MERman) and the Manchester Fungal Infection Group (MFIG, http://www.inflammation-repair.manchester.ac.uk/mfig). 

 

My main research interests are: One Health and Fungal infections, Antimicrobial Resistance (AMR), Climate change and Genetic tools in non-model organisms (Fungal pathogens)

Biography

I started my Research career at the University of Manchester obtaining my PhD. This project was focused on transcriptional regulation during Aspergillus fumigatus infection of the mammalian lung through high-throughput screening of mutants. As an example, we screened the library for azole sensitivity and resistance where my passion for AMR came from.

During my PhD project we have developed CRISPR methodologies for genome editing of A. fumigatus. The focus was on CRISPR-mediated protein tagging and point mutations to avoid using dominant selection markers during transformation. This methodology is widely adopted now in several research laboratories and is still driving much of my research.

I am currently working on a project linking climate change to antifungal resistance, working on dual-use fungicides and novel antifungals. I work on evolution in soil through various techniques combining environmental microbiology, molecular fungal biology and infection biology.

 

Qualifications

2010-2014: BSc (Hons) Biology, Leiden University, the Netherlands

2014-2015: MSc (Dis) Medical Mycology, University of Manchester, United Kingdom

2015-2019: PhD in Molecular Biology, University of Manchester, United Kingdom

Memberships of committees and professional bodies

Microbiology Society (Member and Local Champion, 2019-2024)

Biochemical Society (Early career, member since 2016)

BSMM, British Society for Medical Mycology (member since 2017)

ISHAM (member since 2019) 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 5 - Gender Equality
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 10 - Reduced Inequalities
  • SDG 13 - Climate Action
  • SDG 17 - Partnerships for the Goals

External positions

Bio ECR Editorial Board, MBio

2024 → …

Student committee member, British Mycological Society

1 Oct 20161 Jan 2020

ECR Executive Member, British Society for Medical Mycology

Research Beacons, Institutes and Platforms

  • Global inequalities

Keywords

  • Mycology
  • Microbiology
  • Aspergillus

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