Research output per year
Research output per year
Currently working towards a doctorate in the field of Regenerative Medicine; supervised by Professor Sue Kimber and Professor Rob Lucas.
My project involves manipulating TGFß signalling in pluripotent stem cells through the novel technology of optogenetics. Precise control of TGFß signalling will enable us to investigate and enhance differentiation of human pluripotent stem cells (hPSCs) towards chondrocytes; which will be important in the development of cell-based therapies for osteoarthritis. The main aims of the project are as follows:
1. Develop and optimise a TGFß signalling system
2. Demonstrate and titrate light-activated TGFß signalling with an associated downstream response
3. Fine-tune light dosage during hPSC differentiation to enhance chondrogenesis
My research is co-funded by the MRC and EPSRC.
Supervised by Prof Sue Kimber and Prof Rob Lucas.
MRes Tissue Engineering for Regenerative Medicine, Distinction, University of Manchester
Bsc (Hons) Biological Sciences, 1st Class, Lancaster University
I regularly contribute to public engagement and outreach activities such as British Science Week, in which myself and other members of the CDT in Regenerative Medicine hosted a stand where we introduced Regenerative Medicine concepts to secondary school students.
I also contribute to the FBMH Doctoral Academy blog: Research Hive. My role as scientific sub-editor involves highlighting current and novel work being performed at the University of Manchester, particularly by PhD students and early career researchers.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, Optogenetic Control of BMP Signalling to Drive hPSC Chondrogenesis, The University of Manchester
20 Sept 2016 → 30 Mar 2021
Award Date: 20 May 2021
Master of Research, Tissue Engineering for Regenerative Medicine, The University of Manchester
21 Sept 2015 → 21 Aug 2016
Award Date: 20 Oct 2016
Bachelor of Science, Biological Sciences, Lancaster University
5 Oct 2010 → 20 Jun 2013
Award Date: 10 Jul 2013
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Student thesis: Phd