Philip Crosbie, MBChB, FRCP (Edin), PhD

Search results

• 2023

  Diagnosis and treatment outcomes from prebronchodilator spirometry performed alongside lung cancer screening in a Lung Health Check programme

  Bradley, C., Boland, A., Clarke, L., Dallinson, N., Eckert, C., Ellames, D., Finn, J., Gabe, R., Hancock, N., Kennedy, M. P., Lindop, J., Mohamed, A., Mullen, G., Murray, R. L., Rogerson, S., Shinkins, B., Simmonds, I., Upperton, S., Wilkinson, A., Crosbie, P. A., & 1 othersCallister, M. E., 1 Jun 2023, In: Thorax. 78, 6, p. 543-550 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Spirometry 100%
  • Lung 66%
  • Health 55%
  • Chronic Obstructive Pulmonary Disease 44%
  • Airway Obstruction 44%

• Diagnostic Accuracy of a Convolutional Neural Network Assessment of Solitary Pulmonary Nodules Compared With PET With CT Imaging and Dynamic Contrast-Enhanced CT Imaging Using Unenhanced and Contrast-Enhanced CT Imaging

  SPUtNIk investigators, 1 Feb 2023, In: Chest. 163, 2, p. 444-454 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Computed Tomography 100%
  • Contrast 81%
  • Lung Cancer 43%
  • Lung Nodule 43%
  • Dynamics 43%

• Optimising eligibility criteria for lung cancer screening

  Crosbie, P. A. J. & Callister, M. E. J., 5 Apr 2023, (E-pub ahead of print) In: The Lancet. Respiratory medicine.

  Research output: Contribution to journal › Comment/debate › peer-review

• Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

  TRACERx Consortium & Crosbie, P., 20 Apr 2023, In: Nature . 616, p. 553-562 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Tumor DNA 100%
  • DNA 100%
  • Patient 55%
  • Plasma 55%
  • Relapse 33%

• Validation of lung cancer polygenic risk scores in a high-risk case-control cohort

  Lebrett, M., Smith, M. J., Crosbie, E., Bowes, J., Byers, H., Evans, D. G. & Crosbie, P., 30 Apr 2023, (Accepted/In press) In: Genetics in Medicine.

  Research output: Contribution to journal › Article › peer-review
• 2022

  Attitudes towards the integration of smoking cessation into lung cancer screening in the United Kingdom: a qualitative study of individuals eligible to attend

  Groves, S., McCutchan, G., Quaife, S. L., Murray, R. L., Ostroff, J. S., Brain, K. E., Crosbie, P., Yorke, J., Baldwin, D., Field, J. K. & McWilliams, L., 15 Apr 2022, (Accepted/In press) In: Health Expectations.

  Research output: Contribution to journal › Article › peer-review

  • Screening 100%
  • Nicotine Withdrawal 83%
  • Lung Cancer Screening 83%
  • Motivation 50%
  • Attitude 33%

• Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context

  Quinn-Scoggins, H. D., Murray, R. L., Quaife, S. L., Smith, P., Brain, K. E., Callister, M. E. J., Baldwin, D. R., Britton, J., Crosbie, P. A. J., Thorley, R. & McCutchan, G. M., Dec 2022, In: BMC Pulmonary Medicine. 22, 1, 478.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Development 100%
  • Smoking 100%
  • Lung 80%
  • Radiation 80%
  • Computer Assisted Tomography 80%

• Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling

  Gilbert, F. J., Harris, S., Miles, K. A., Weir-McCall, J. R., Qureshi, N. R., Rintoul, R. C., Dizdarevic, S., Pike, L., Sinclair, D., Shah, A., Eaton, R., Clegg, A., Benedetto, V., Hill, J. E., Cook, A., Tzelis, D., Vale, L., Brindle, L., Madden, J., Cozens, K., & 17 othersLittle, L. A., Eichhorst, K., Moate, P., McClement, C., Peebles, C., Banerjee, A., Han, S., Poon, F. W., Groves, A. M., Kurban, L., Frew, A. J., Callister, M. E., Crosbie, P., Gleeson, F. V., Karunasaagarar, K., Kankam, O. & George, S., 1 Mar 2022, In: Health technology assessment (Winchester, England). 26, 17, p. 7-118 112 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Computed Tomography 100%
  • Positron Emission Tomography 52%
  • Lung Nodule 26%
  • Patient 17%
  • Diagnostic Accuracy 17%

• Early Diagnosis and Lung Cancer Screening

  Balata, H., Quaife, S. L., Craig, C., Ryan, D. J., Bradley, P., Crosbie, P. A. J., Murray, R. L. & Evison, M., Nov 2022, In: Clinical Oncology. 34, 11, p. 708-715 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung Cancer 100%
  • Screening 50%
  • Lung Cancer Screening 50%
  • Symptom 50%
  • Early Diagnosis 50%

• Explaining differences in the frequency of lung cancer detection between the National Lung Screening Trial and community-based screening in Manchester, UK

  Robbins, H. A., Zahed, H., Lebrett, M. B., Balata, H., Johansson, M., Sharman, A., Evans, D. G., Crosbie, E. J., Booton, R., Landy, R. & Crosbie, P. A. J., 1 Sep 2022, In: Lung Cancer.

  Research output: Contribution to journal › Article › peer-review

  • National Lung Screening Trial 100%
  • Health 80%
  • Lung 80%
  • Lung Cancer 70%
  • Screening 40%

• Incidental findings in low dose CT lung cancer screening of high-risk smokers: Results from the Manchester lung Health Check pilot

  Bradley, P., Bola, B. M., Balata, H., Sharman, A., Booton, R. & Crosbie, P. A. J., Nov 2022, In: Lung Cancer. 173, p. 1-4 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lung Cancer Screening 100%
  • Health 66%
  • Lung 66%
  • Computed Tomography 66%
  • Cancer 66%

• Likely uptake of a future a lung cancer screening programme in Hodgkin lymphoma survivors: a questionnaire study

  Broadbent, R., Armitage, C. J., Crosbie, P., Radford, J. & Linton, K., 28 Apr 2022, In: BMC Pulmonary Medicine. 22, 1, p. 165 165.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lung Cancer Screening 100%
  • Hodgkin's Lymphoma 72%
  • Screening 45%
  • Lung Cancer 45%
  • Smoking 27%

• Lung cancer screening in 2022: a narrative review

  Bradley, P., Taylor, M., Ugolini, S., Crosbie, P. A. J., Granato, F., Balata, H. & Booton, R., Sep 2022, In: Video-Assisted Thoracic Surgery. 7, 14.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Screening 100%
  • Lung Cancer 62%
  • Lung Cancer Screening 62%
  • Therapeutic Procedure 25%
  • Diseases 25%

• Participation in community-based lung cancer screening: the Yorkshire Lung Screening Trial

  Crosbie, P., Gabe, R., Simmonds, I., Hancock, N., Alexandris, P., Kennedy, M., Rogerson, S., Baldwin, D., Booton, R., Bradley, C., Darby, M., Eckert, C., Franks, K. N., Lindop, J., Janes, S. M., Møller, H., Murray, R. L., Neal, R. D., Quaife, S. L., Upperton, S., & 3 othersShinkins, B., Tharmanathan, P. & Callister, M. E. J., 2022, In: European Respiratory Journal.

  Research output: Contribution to journal › Article › peer-review

  • Screening 100%
  • Lung 85%
  • Health 57%
  • Computer Assisted Tomography 42%
  • Low Drug Dose 42%

• Risk perception and disease knowledge in attendees of a community-based lung cancer screening programme

  Lebrett, M. B., Crosbie, E. J., Yorke, J., Hewitt, K., Rowlands, A., Badrick, E., Evans, D. G., Balata, H., Booton, R. & Crosbie, P. A. J., 6 Apr 2022, In: Lung Cancer.

  Research output: Contribution to journal › Article › peer-review

  • Lung Cancer 100%
  • Screening 83%
  • Age 33%
  • Diseases 33%
  • Cancer Risk 33%

• The diagnostic pathway in lung cancer patients with best supportive care decisions: are there lessons to be learnt?

  King, J., Shah, D., Hewitt, K., Punjabi, A., Marshall, K., Balata, H., Brockelsby, C., Sinnott, N., Lyons, J., Martin, J., Crosbie, P., Booton, R., Ng, C., Cove-Smith, L. & Evison, M., May 2022, In: Clinical medicine (London, England). 22, 3, p. 246-250 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Supportive Care 100%
  • Patient 90%
  • Lung Cancer 60%
  • Computer Assisted Tomography 30%
  • Diagnosis 20%

• The Yorkshire Kidney Screening Trial (YKST): protocol for a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other abdominal pathology within a trial of community-based CT screening for lung cancer

  Usher-Smith, J. A., Godoy, A., Burge, S. W., Burbidge, S., Cartledge, J., Crosbie, P. A. J., Eckert, C., Farquhar, F., Hammond, D., Hancock, N., Iball, G. R., Kimuli, M., Masson, G., Neal, R. D., Rogerson, S., Rossi, S. H., Sala, E., Smith, A., Sharp, S. J., Simmonds, I., & 4 othersWallace, T., Ward, M., Callister, M. E. J. & Stewart, G. D., 20 Sep 2022, In: BMJ Open. 12, 9, e063018.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Screening 100%
  • Computed Tomography 57%
  • Lung 42%
  • Cancer Cell 35%
  • Kidney 35%
• 2021

  Analysis of the baseline performance of five UK lung cancer screening programmes

  Balata, H., Ruparel, M., O'Dowd, E., Ledson, M., Field, J. K., Duffy, S. W., Quaife, S. L., Sharman, A., Janes, S., Baldwin, D., Booton, R. & Crosbie, P. A. J., 1 Nov 2021, In: Lung cancer (Amsterdam, Netherlands). 161, p. 136-140 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Screening 100%
  • Lung Cancer 70%
  • Surgery 50%
  • Low Drug Dose 40%
  • False Positive Result 30%

• Biomarkers in lung cancer screening: the importance of study design

  Baldwin, D. R., Callister, M. E., Crosbie, P. A., O'Dowd, E. L., Rintoul, R. C., Robbins, H. A. & Steele, R. J. C., 14 Jan 2021, In: The European respiratory journal. 57, 1, 2004367.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  • Screening 100%
  • Biological Marker 75%
  • Age 50%
  • Lung Cancer Screening 50%
  • Smoking 50%

• Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom

  Robbins, H. A., Alcala, K., Swerdlow, A. J., Schoemaker, M. J., Wareham, N., Travis, R. C., Crosbie, P. A. J., Callister, M., Baldwin, D. R., Landy, R. & Johansson, M., 8 Jun 2021, In: British Journal of Cancer. 124, 12, p. 2026-2034 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lung 100%
  • Lung Cancer 80%
  • Screening 60%
  • Cancer Risk 40%
  • Aptitude 20%

• Correction: Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom (British Journal of Cancer, (2021), 124, 12, (2026-2034), 10.1038/s41416-021-01278-0)

  Robbins, H. A., Alcala, K., Swerdlow, A. J., Schoemaker, M. J., Wareham, N., Travis, R. C., Crosbie, P. A. J., Callister, M., Baldwin, D. R., Landy, R. & Johansson, M., 20 Jul 2021, In: British Journal of Cancer. 125, 2, p. 305 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Screening 100%
  • Lung 100%
  • Lung Cancer 100%
  • Cancer Risk 100%
  • Malignant Neoplasm 50%

• Establishing scanning protocols for a CT lung cancer screening trial in the UK

  Iball, G. R., Darby, M., Gabe, R., Crosbie, P. A. J. & Callister, M. E. J., 1 Dec 2021, In: The British journal of radiology. 94, 1128, 20201343.

  Research output: Contribution to journal › Article › peer-review

  • Image Quality 100%
  • Phantom 88%
  • Lung 66%
  • Screening 55%
  • Biological Marker 44%

• Impact of solitary pulmonary nodule size on qualitative and quantitative assessment using 18F-fluorodeoxyglucose PET/CT: the SPUTNIK trial

  SPUtNIk investigators, May 2021, In: European Journal of Nuclear Medicine and Molecular Imaging. 48, 5, p. 1560-1569 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diagnosis 100%
  • PET-CT 80%
  • Lung Nodule 60%
  • Assessment 40%
  • Blood 40%

• Performance monitoring of EBUS for the staging and diagnosis of lung cancer: Auditing the greater manchester ebus service against new national standards

  Punjabi, A., Al-Najjar, H., Teng, B., Borrill, Z., Brown, L., Nagarajan, T., Gallagher, J., Grundy, S., Sundar, R., Higgins, C., Shackley, D., Sinnott, N., Balata, H., Lyons, J., Martin, J., Brocklesby, C., Crosbie, P., Booton, R. & Evison, M., 25 Jun 2021, In: BMJ Open Respiratory Research. 8, 1, e000777.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endobronchial Ultrasonography 100%
  • Lung Cancer 33%
  • Diagnosis 25%
  • Malignant Neoplasm 25%
  • Monitoring 16%

• Targeting lung cancer screening to individuals at greatest risk: the role of genetic factors

  Lebrett, M., Crosbie, E., Smith, M. J., Woodward, E., Evans, D. G. & Crosbie, P., 1 Apr 2021, In: Journal of Medical Genetics. 58, 4, p. 217-226 10 p., 107399.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lung Cancer 100%
  • Screening 71%
  • Lung Cancer Screening 57%
  • Genetic Risk Factor 42%
  • Penetrance 28%
• 2020

  Analysis of lung cancer risk model (PLCOM2012 and LLPv2) performance in a community-based lung cancer screening programme

  Lebrett, M., Balata, H., Evison, M., Colligan, D., Duerden, R., Elton, P., Greaves, M., Howells, J., Irion, K., Karunaratne, D., Lyons, J., Mellor, S., Myerscough, A., Newton, T., Sharman, A., Smith, E., Taylor, B., Taylor, S., Walsham, A., Whittaker, J., & 5 othersBarber, P. V., Tonge, J., Robbins, H. A., Booton, R. & Crosbie, P., 2020, In: Thorax.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Screening 100%
  • Lung Cancer 63%
  • National Lung Screening Trial 45%
  • Health 27%
  • Analysis 18%

• Attending community-based lung cancer screening influences smoking behaviour in deprived populations

  Balata, H., Traverse-Healy, L., Blandin-Knight, S., Armitage, C., Barber, P., Colligan, D., Elton, P., Kirwan, M., Lyons, J., McWilliams, L., Novasio, J., Sharman, A., Slevin, K., Taylor, S., Tonge, J., Waplington, S., Yorke, J., Evison, M., Booton, R. & Crosbie, P. A. J., Jan 2020, In: Lung Cancer. 139, p. 41-46 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Smoking 100%
  • Screening 41%
  • Health 33%
  • Lung 33%
  • Lung Cancer Screening 33%

• Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

  TRACERx Consortium, 5 Mar 2020, In: Nature Genetics. 52, 3, p. 283-293 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Evolution 100%
  • Loss of Heterozygosity 100%
  • Sequencing 50%
  • Mutation 50%
  • Tumor Suppressor Gene 50%

• Publisher Correction: A clonal expression biomarker associates with lung cancer mortality (Nature Medicine, (2019), 25, 10, (1540-1548), 10.1038/s41591-019-0595-z)

  TRACERx Consortium, 1 Jul 2020, In: Nature Medicine. 26, 7, p. 1148-1148 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Biological Marker 100%
  • Lung Cancer 100%
  • Error 100%
  • Cancer Mortality 100%
  • Nature Medicine 100%

• Spirometry performed as part of the Manchester community-based lung cancer screening programme detects a high prevalence of airflow obstruction in individuals without a prior diagnosis of COPD

  Balata, H., Harvey, J., Barber, P., Colligan, D., Duerdan, R., Elton, P., Evison, M., Greaves, M., Howells, J., Irion, K., Karunaratne, D., Mellor, S., Newton, T., Sawyer, R., Sharman, A., Smith, E., Taylor, B., Taylor, S., Tonge, J., Walsham, A., & 4 othersWhittaker, J., Vestbo, J., Booton, R. & Crosbie, P., 8 May 2020, (Accepted/In press) In: Thorax.

  Research output: Contribution to journal › Article › peer-review

  • Diagnosis 100%
  • Chronic Obstructive Pulmonary Disease 100%
  • Airway Obstruction 85%
  • Screening 71%
  • Spirometry 71%

• The Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low dose computed tomography screening for lung cancer versus usual care in a targeted population at risk.

  Crosbie, P., Gabe, R., Simmonds, I., Kennedy, M., Rogerson, S., Ahmed, N., Baldwin, D., Booton, R., Cochrane, A., Darby, M., Franks, K., Hinde, S., Janes, S. M., MacLeod, U., Messenger, M., Møller, H., Murray, R. L., Neal, R. D., Quaife, S. L., Sculpher, M., & 3 othersTharmanathan, P., Torgerson, D. & Callister, M. E. J., 8 Jul 2020, (Accepted/In press) In: BMJ Open.

  Research output: Contribution to journal › Article › peer-review

  • Screening 100%
  • Lung Cancer 62%
  • Lung 50%
  • Health 37%
  • Computer Assisted Tomography 37%

• Yorkshire Enhanced Stop Smoking (YESS) study: a protocol for a randomised controlled trial to evaluate the effect of adding a personalised smoking cessation intervention to a lung cancer screening programme

  Murray, R. L., Brain, K., Britton, J., Quinn-Scoggins, H. D., Lewis, S., McCutchan, G. M., Quaife, S. L., Wu, Q., Ashurst, A., Baldwin, D., Crosbie, P. A. J., Neal, R. D., Parrott, S., Rogerson, S., Thorley, R. & Callister, M. E., 10 Sep 2020, In: BMJ Open. 10, 9, p. e037086

  Research output: Contribution to journal › Article › peer-review

  • Nicotine Withdrawal 100%
  • Screening 50%
  • Smoking 50%
  • Lung 40%
  • Health 20%
• 2019

  Attendees of Manchester’s Lung Health Check pilot express a preference for community-based lung cancer screening.

  Crosbie, P., 2019, In: Thorax.

  Research output: Contribution to journal › Article › peer-review

  • Screening 100%
  • Smoking 100%
  • Health 66%
  • Lung 66%
  • Hospital 66%

• CT screening for lung cancer: Are we ready to implement in Europe?

  Balata, H., Evison, M., Sharman, A., Crosbie, P. & Booton, R., 1 Aug 2019, In: Lung Cancer. 134, p. 25-33 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Screening 100%
  • Computed Tomography 100%
  • Lung Cancer Screening 100%
  • Low Drug Dose 66%
  • Base 33%

• Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients

  Geary, B., Walker, M. J., Snow, J. T., Lee, D., Pernemalm, M., Maleki-Dizaji, S., Azadbakht, N., Apostolidou, S., Barnes, J., Krysiak, P., Shah, R., Booton, R., Dive, C., Crosbie, P. A. & Whetton, A. D., 2019, In: Journal of Proteome Research. 18, 9, p. 3369-3382 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein 100%
  • Mass Spectrometry 75%
  • Sample 50%
  • Experiment 25%
  • Spectrum 25%

• Neoantigen-directed immune escape in lung cancer evolution

  The TRACERx consortium, 2019, In: Nature. 567, 7749, p. 479-485 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunity 100%
  • Neoantigen 71%
  • Lung 42%
  • Cells 28%
  • Evolution 28%

• Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

  TRACERx Consortium, 7 Oct 2019, In: Nature Medicine. 25, 10, p. 1534-1539 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Surgery 100%
  • Relapse 100%
  • Non Small Cell Lung Cancer 80%
  • Patient 60%
  • Diseases 60%

• Pulmonary venous tumour cells disseminating prior to tumour resection are associated with relapse and seed future metastasis.

  Crosbie, P., Oct 2019, In: Nature Medicine.

  Research output: Contribution to journal › Article › peer-review

• Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

  Crosbie, P. A., Balata, H., Evison, M., Atack, M., Bayliss-brideaux, V., Colligan, D., Duerden, R., Eaglesfield, J., Edwards, T., Elton, P., Foster, J., Greaves, M., Hayler, G., Higgins, C., Howells, J., Irion, K., Karunaratne, D., Kelly, J., King, Z., Lyons, J., & 23 othersManson, S., Mellor, S., Miller, D., Myerscough, A., Newton, T., O’leary, M., Pearson, R., Pickford, J., Sawyer, R., Screaton, N. J., Sharman, A., Simmons, M., Smith, E., Taylor, B., Taylor, S., Walsham, A., Watts, A., Whittaker, J., Yarnell, L., Threlfall, A., Barber, P. V., Tonge, J. & Booton, R., 2019, In: Thorax.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Screening 100%
  • Lung Cancer Screening 100%
  • Health 66%
  • Lung 66%
  • Lung Cancer 66%

• The potential of breath analysis to improve outcome for patients with lung cancer.

  Crosbie, P., Antoniou, S. X., Gaude, E., Ruparel, M., van der Schee, M. P., Janes, S. M. & Rintoul, M. C., 24 Apr 2019, In: Journal of Breath Research. 13, 3

  Research output: Contribution to journal › Review article › peer-review

  • Lung Cancer 100%
  • Breathing 83%
  • Breath Analysis 50%
  • Volatile Organic Compound 50%
  • Electric Potential 50%

• "To know or not to know horizontal ellipsis ?" Push and pull in ever smokers lung screening uptake decision-making intentions

  Tonge, J. E., Atack, M., Crosbie, P. A., Barber, P. V., Booton, R. & Colligan, D., Apr 2019, In: Health Expectations. 22, 2, p. 162-172 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Smoking 100%
  • Lung 81%
  • Screening 72%
  • Decision Making 36%
  • Health 27%

• Top Ten Research Priorities for Detecting Cancer Early

  Renehan, A., Crosbie, E., Crosbie, P. & Detecting Cancer Early PSP steering group, 2019, In: The Lancet Public Health.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors

  Crosbie, P., 2018, In: International Journal of Cancer.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cells 100%
  • Lung Cancer 80%
  • Neoplasm 60%
  • Epithelial Cell 60%
  • Malignant Neoplasm 60%
  98 Downloads (Pure)

• Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

  Arce Vargas, F., Furness, A. J. S., Litchfield, K. & Crosbie, P., 2018, In: Cancer Cell.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Monospecific Antibody 100%
  • Regulatory T Cell 100%
  • Ipilimumab 100%
  • Mouse Model 50%
  • Isotype 50%

• Implementing lung cancer screening: baseline results from a community-based ‘Lung Health Check’ pilot in deprived areas of Manchester.

  Crosbie, P., Balata, H., Evison, M., Bayliss-Brideaux, V., Colligan, D., Duerden, R., Eaglesfield, J., Elton, P., Foster, J., Greaves, M., Hayler, G., Higgins, C., Howells, J., Irion, K., Karunaratne, D., Kelly, J., Z, K., Manson, S., Mellor, S., Miller, D., & 20 othersMyerscough, A., Newton, T., O'Leary, M., Pearson, R., Pickford, J., Sawyer, R., Screaton, N., Sharman, A., Simons, M., Smith, E., Taylor, B., Taylor, S., Walsham, A., Watts, A., Whittaker, J., Yarnell, L., Threlfall, A., Barber, PV., Tonge, J. & Booton, R., 13 Feb 2018, In: Thorax. 74, 4, p. 405-409 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Health 100%
  • Lung 100%
  • Lung Cancer Screening 100%
  • Computed Tomography 66%
  • Low Drug Dose 66%
  100 Downloads (Pure)

• KRAS induces lung tumorigenesis through microRNAs modulation

  Crosbie, P., Shi, L., Middleton, J. D., Magee, P., Laganá, A., Leong, H. S., Sahoo, S., Fassan, M., Booton, R., Shah, R. & Garofalo, M., 2018, In: CELL DEATH & DISEASE.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • KRAS 100%
  • MicroRNA 60%
  • Development 40%
  • Gene Expression 20%
  • Mouse 20%

• Predicting survival following surgical resection of lung cancer using clinical and pathological variables: The development and validation of the LNC-PATH score

  Balata, H., Foden, P., Edwards, T., Chaturvedi, A., Elshafi, M., Tempowski, A., Teng, B., Whittemore, P., Blyth, K. G., Kidd, A., Ellames, D., Flint, L. A., Robson, J., Teh, E., Jones, R., Batchelor, T., Crosbie, P., Booton, R. & Evison, M., Nov 2018, In: Lung Cancer. 125, p. 29-34

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  133 Downloads (Pure)

• Prevalence of nodal metastases in lymph node stations 8 & 9 in a large UK lung cancer surgical centre without routine pre-operative EUS nodal staging

  Evison, M., Edwards, T., Balata, H., Tempowski, A., Teng, B., Bishop, P., Fontaine, E., Krysiak, P., Rammohan, K., Shah, R., Crosbie, P. & Booton, R., 1 Jan 2018, In: Lung Cancer. 115, p. 127-130 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Endoscopic Ultrasound 100%
  • Patient 85%
  • Diseases 71%
  • Lymph Node 71%
  • Enalapril Maleate 57%

• Targeted lung cancer screening selects individuals at high risk of cardiovascular disease.

  Balata, H., Knight, S., Barber, P., Colligan, D., Crosbie, E., Duerdan, R., Elton, P., Evison, M., Greaves, M., Howells, J., Irion, K., Karunaratne, D., Kirwan, M., Macnab, A., Mellor, S., Miller, C., Newton, T., Novasio, J., Sawyer, R., Sharman, A., & 10 othersSlevin, K., Smith, E., Taylor, B., Taylor, S., Tonge, J., Walsham, A., Waplington, S., Whittaker, J., Booton, R. & Crosbie, P., Oct 2018, In: Lung Cancer. 124, p. 148-153 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Screening 100%
  • Cardiovascular Disease 71%
  • Lung Cancer Screening 57%
  • Age 42%
  • Lung Cancer 28%
  382 Downloads (Pure)

• The cost-effectiveness of the Manchester ‘lung health checks’, a community-based lung cancer low-dose CT screening pilot

  Hinde, S., Crilly, T., Balata, H., Bartlett, R., Crilly, J., Barber, P., Threlfall, A., Tonge, J., Booton, R. & Crosbie, P. A., Dec 2018, In: Lung Cancer. 126, p. 119-124 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Health Care Cost 100%
  • Screening 100%
  • Computed Tomography 100%
  • Low Drug Dose 100%
  • Patient 80%