Research output per year
Research output per year
My area of research is complex disease genetics. This applies to conditions where multiple genes interplay with environmental triggers.
I use both genetic and functional approaches to further the understanding of:
(i) The commonest inflammatory arthritis to affect children under 16 years – Juvenile Idiopathic Arthritis.
(ii) Changes that arise with weight variation a. Obesity
b. Bariatric surgery
c. Diabetes (T2DM, T1D, GDM)
(iii) Inflammatory pathologies, especially where variation in steroid sensitivity is a factor (eg SLE).
Rachelle Donn MB ChB PhD
Expertise in: Molecular Genetics and Functional Genomics.
Main Research interests:
1) Genetics of complex diseases (Juvenile Idiopathic Arthritis, Diabetes, Systemic Lupus Erythematosus)
2) Genetic basis of drug response (Steroids)
3) Network analysis of complex genetic diseases
The focus of my research is (i) the identification of novel markers for early identification of common chronic diseases (ii) translation of the basic science observations into patient benefit.
Research interests include:
(i) Genetic basis of common diseases. Juvenile Idiopathic Arthritis (JIA) used as model of a chronic, relapsing and remitting, inflammatory disease. Type 2 diabetes/obesity
(ii) Functional Genomics, as a way of extending the observations made from traditional genetic association studies.
(iii) Systems based analyses
Keywords:
Complex Genetics, Inflammation, Arthritis, Diabetes, Obesity, Bariatric Surgery
I have several leadership / senior management roles within Manchester Medical School
These include:
Associate Director for Student Progression 2018-
Personal Excellence Pathway Associate Lead (Years 1-5) 2017-
Deputy Director of Studies (Years 1&2) 2014-2017
Academic Lead for Attendance & Professionalism (Years 1&2) 2014-2017
Year 1 Lead for Peer Mentor Scheme 2016-
Phase 1 Lead Hospital Allocations Mitigations Panel 2015-
Module Lead for Semester 1 of MB ChB 2011-
Module Lead for Smester 4 of MB ChB 2014-15
MB ChB PBL Tutor 2011-
Semester 1 Lecturer 2011 -
Communication and Clinical Skills Tutor (MB ChB, Phase I) 2012-
Dr Handrean Soren
Dr Adam Stevens
Dr Kirk Siddals
Professor William Ollier
Professor Martin Gibson
The Healthy City Initiative is a long term, sustainable endeavour to improve the health of Salford residents, principally by educating and monitoring in relation to type 2 diabetes. This has fed forwards into more funding coming to Salford for extended projects related to wider, related public health issues such as the national diabetes prevention programme. I am chair of the streeing group for the Healthy City Initiative and liaise regularly with Diabetes UK in relation to this long term project.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Conference article
Adam, Safwaan (Recipient), Liu, Yifen (Recipient), Siah Mansur, Tarza (Recipient), Ho, Jan Hoong (Recipient), Azmi, Shazli (Recipient), Siddals, Kirk (Recipient), Dhage, Shaishav (Recipient), Malik, Rayaz (Recipient), Syed, Akheel (Recipient), Ammori, Basil (Recipient), Durrington, Paul (Recipient), Donn, Rachelle (Recipient) & Soran, Handrean (Recipient), 26 Jan 2018
Prize: Prize (including medals and awards)
Akheel Syed, Safwaan Adam, Handrean Soran, Philip Kalra, Rayaz Malik & Rachelle Donn
30/10/20
1 item of Media coverage
Press/Media: Research