Rebecca Bromley

2024

Discovery of DNA methylation signature in the peripheral blood of individuals with history of antenatal exposure to valproic acid

Haghshenas, S., Putoux, A., Reilly, J., Levy, M. A., Relator, R., Ghosh, S., Kerkhof, J., McConkey, H., Edery, P., Lesca, G., Besson, A., Coubes, C., Willems, M., Ruiz-Pallares, N., Barat-Houari, M., Tizzano, E. F., Valenzuela, I., Sabbagh, Q., Clayton-Smith, J. & Jackson, A. & 5 others, O'Sullivan, J., Bromley, R., Banka, S., Genevieve, D. & Sadikovic, B., 1 Oct 2024, In: Genetics in medicine : official journal of the American College of Medical Genetics. 26, 10, 101226.

Research output: Contribution to journal › Article › peer-review

Open Access

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Epilepsy-pregnancy registries: An update

Perucca, P., Battino, D., Bromley, R., Chen, L., Craig, J., Hernandez-Diaz, S., Holmes, L. B., Koshy, K. G., Meador, K. J., Menon, R. N., O'Brien, T. J., Pennell, P. B., Zhou, D. & Tomson, T., 14 Nov 2024, (E-pub ahead of print) In: Epilepsia.

Research output: Contribution to journal › Article › peer-review

Neurodevelopmental outcomes of infants after in utero exposure to SARS-CoV-2 or mRNA COVID-19 vaccine compared to unexposed infants: a COVI-PREG prospective cohort study

Favre, G., Bromley, R. L., Bluett-Duncan, M., Maisonneuve, E., Pomar, L., Daire, C., Radan, A.-P., Raio, L., Surbek, D., Blume, C., Kalimeris, S., Madec, Y., Schneider, J., Graz, M. B., Winterfeld, U., Panchaud, A. & Baud, D., 23 Oct 2024, (E-pub ahead of print) In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Research output: Contribution to journal › Article › peer-review

Preconception counselling in women with epilepsy

Pegg, E., Bromley, R., Mirza, F. & Campbell, E., 27 Jun 2024, In: Practical Neurology.

Research output: Contribution to journal › Article › peer-review

Prenatal Exposure to Antiseizure Medications and Risk of Epilepsy in Children of Mothers With Epilepsy

Dreier, J. W., Christensen, J., Igland, J., Gissler, M., Leinonen, M. K., Vegrim, H. M., Sun, Y., Tomson, T., Zoega, H., Bjørk, M.-H. & Bromley, R. L., 5 Feb 2024, In: JAMA Network Open. 7, 2, e2356425.

Research output: Contribution to journal › Article › peer-review

Open Access

The lived experience of young adults with Fetal Valproate Spectrum Disorder, and the perspective of their parents: A qualitative study

Khanom, S., Astill, D., Astill, N., Cozens, J., Mann, B., Garratt, J. & Bromley, R. L., Mar 2024, In: Epilepsy & Behavior . 152, 109680.

Research output: Contribution to journal › Article › peer-review

Open Access

The use of parent‐completed questionnaires to investigate developmental outcomes in large populations of children exposed to antiseizure medications in pregnancy

Bluett‐Duncan, M., Bullen, P., Campbell, E., Clayton‐Smith, J., Craig, J., García‐Fiñana, M., Hughes, D. M., Ingham, A., Irwin, B., Jackson, C., Kelly, T., Morrow, J., Rushton, S., Winterbottom, J., Wood, A. G., Yates, L. M. & Bromley, R. L., 16 Jul 2024, In: Epilepsia. 65, 7, p. 2017-2029 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Adaptive behaviour in children exposed to topiramate in the womb: an observational cohort study

Knight, R., Craig, J., Irwin, B., Wittkowski, A. & Bromley, R. L., 1 Feb 2023, In: Seizure. 105, p. 56-64 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Core Data Elements for Pregnancy Pharmacovigilance Studies Using Primary Source Data Collection Methods: Recommendations from the IMI ConcePTION Project

Richardson, J. L., Moore, A., Bromley, R. L., Stellfeld, M., Geissbühler, Y., Bluett-Duncan, M., Winterfeld, U., Favre, G., Alexe, A., Oliver, A. M., van Rijt-Weetink, Y. R. J., Hodson, K. K., Rezaallah, B., van Puijenbroek, E. P., Lewis, D. J. & Yates, L. M., 28 Mar 2023, In: Drug Safety.

Research output: Contribution to journal › Article › peer-review

Open Access

Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies

Bromley, R. L., Bickle Graz, M., Bluett-Duncan, M., Damkier, P., Dietrich, K., Dolk, H., Mattson, S., Meador, K. J., Nordeng, H., Oberlander, T. F., Ornoy, A., Revet, A., Rovet, J., Schuler-Faccini, L., Smearman, E., Simms, V., Vorhees, C., Wide, K., Ystrom, E. & Supraja, T. A., 1 Jun 2023, In: Frontiers in Pharmacology. 14, 1094698.

Research output: Contribution to journal › Article › peer-review

Open Access

Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child

Bromley, R., Adab, N., Bluett-Duncan, M., Clayton-Smith, J., Christensen, J., Edwards, K., Greenhalgh, J., Hill, R. A., Jackson, C. F., Khanom, S., McGinty, R. N., Tudur Smith, C., Pulman, J. & Marson, A. G., 29 Aug 2023, In: Cochrane Database of Systematic Reviews. 8, 11, p. 1-355 355 p., CD010224.

Research output: Contribution to journal › Article › peer-review

Open Access

Neurodevelopmental outcomes in children and adults with Fetal Valproate Spectrum Disorder: A contribution from the ConcePTION project

Bluett-Duncan, M., Astill, D., Charbak, R., Clayton-Smith, J., Cole, S., Cook, P. A., Cozens, J., Keely, K., Morris, J., Mukherjee, R., Murphy, E., Turnpenny, P., Williams, J., Wood, A. G., Yates, L. M. & Bromley, R. L., 1 Nov 2023, In: Neurotoxicology and Teratology. 100, 107292.

Research output: Contribution to journal › Article › peer-review

Open Access

Neurodevelopment of babies born to mothers with epilepsy: a prospective observational cohort study

NaME Study Group, Bromley, R. L., Bullen, P., Campbell, E., Craig, J., Ingham, A., Irwin, B., Jackson, C., Kelly, T., Morrow, J., Rushton, S., García-Fiñana, M., Hughes, D. M., Winterbottom, J., Wood, A., Yates, L. M. & Clayton-Smith, J., 19 Sept 2023, In: Epilepsia. 64, 9, p. 2454-2471 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

An inventory of European data sources to support pharmacoepidemiologic research on neurodevelopmental outcomes in children following medication exposure in pregnancy: A contribution from the ConcePTION project

Given, J., Bromley, R. L., Coste, F., Lopez-Leon, S. & Loane, M., 20 Oct 2022, In: PLoS ONE. 17, 10 October, e0275979.

Research output: Contribution to journal › Article › peer-review

Open Access

Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force

Tomson, T., Battino, D., Bromley, R., Kochen, S., Meador, K. J., Pennell, P. B. & Thomas, S. V., 1 Dec 2022, In: Epileptic Disorders. 24, 6, p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Zonisamide safety in pregnancy: Data from the UK and Ireland epilepsy and pregnancy register

McCluskey, G., Kinney, M. O., Russell, A., Smithson, W. H., Parsons, L., Morrison, P. J., Bromley, R., MacKillop, L., Heath, C., Liggan, B., Murphy, S., Delanty, N., Irwin, B., Campbell, E., Morrow, J., Hunt, S. J. & Craig, J. J., 1 Oct 2021, In: Seizure. 91, p. 311-315 5 p.

Research output: Contribution to journal › Article › peer-review

2020

Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy

Tomson, T., Battino, D., Bromley, R., Kochen, S., Meador, K. J., Pennell, P. B. & Thomas, S. V., 1 Sept 2020, In: Epilepsia open. 5, 3, p. 366-370 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability

Clayton-Smith, J., Bromley, R., Dean, J., Journel, H., Odent, S., Wood, A., Williams, J., Cuthbert, V., Hackett, L., Aslam, N., Malm, H., James, G., Westbom, L., Day, R., Ladusans, E., Jackson, A., Bruce, I., Walker, R., Sidhu, S. & Dyer, C. & 6 others, Ashworth, J., Hindley, D., Diaz, G. A., Rawson, M., Turnpenny, P. & Jackson, A., 2019, In: Orphanet Journal of Rare Diseases. 14, 1, p. 180

Research output: Contribution to journal › Article › peer-review

Open Access

Effects of periconceptional folate on cognition in children of women with epilepsy: NEAD study

NEAD Investigator Group, Meador, K. J., Pennell, P. B., May, R. C., Brown, C. A., Baker, G., Bromley, R., Loring, D. W. & Cohen, M. J., 2019, In: Neurology.

Research output: Contribution to journal › Article › peer-review

Open Access

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Executive Summary: Management of epilepsy in pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy

Tomson, T., Battino, D., Bromley, R., Kochen, S., Meador, K., Pennell, P. & Thomas, S. V., Dec 2019, In: Epilepsia. 60, 12, p. 2343-2345 3 p.

Research output: Contribution to journal › Article

Open Access

Exome sequencing in patients with antiepileptic drug exposure and complex phenotypes

DDD Study, 3 Sept 2019, In: Archives of Disease in Childhood.

Research output: Contribution to journal › Article › peer-review

Open Access

Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study

NEAD Study Group, 1 Mar 2019, In: Epilepsy and Behavior. 92, p. 154-164 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Intellectual functioning in clinically confirmed fetal valproate syndrome

Bromley, R. L., Baker, G. A. & Clayton-Smith, J., 1 Jan 2019, In: Neurotoxicology and Teratology. 71, p. 16-21 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy

Tomson, T., Battino, D., Bromley, R., Kochen, S., Meador, K., Pennell, P. & Thomas, S. V., 1 Dec 2019, In: Epileptic Disorders. 21, 6, p. 497-517 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Use and validity of child neurodevelopment outcome measures in studies on prenatal exposure to psychotropic and analgesic medications - A systematic review

Hjorth, S., Bromley, R., Ystrom, E., Lupattelli, A., Spigset, O. & Nordeng, H., 11 Jul 2019, In: PLoS ONE. 14, 7, p. e0219778

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Changing antiepilepsy drug-prescribing trends in women with epilepsy in the UK and Ireland and the impact on major congenital malformations

Kinney, M. O., Morrow, J., Patterson, C. C., Campbell, E., Russell, A., Smithson, H. W., Parsons, L., Morrison, P. J., Bromley, R., Liggan, B., Delanty, N., Irwin, B., Hunt, S. J. & Craig, J. J., 2018, In: Journal of Neurology, Neurosurgery & Psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

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2017

Fetal antiepileptic drug exposure and cognitive outcomes

Bromley, R. & Baker, G., Jan 2017, In: Seizure: European Journal of Epilepsy. 44, p. 225-231

Research output: Contribution to journal › Article › peer-review

Open Access

4 Downloads (Pure)

Maternal use of antiepileptic agents during pregnancy and major congenital malformations in children

Bromley, R., Marson, A. G. & Weston, J., 7 Nov 2017, In: JAMA: The Journal of the American Medical Association . 318, 17, p. 1700-1701

Research output: Contribution to journal › Article › peer-review

Open Access

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Sensitivity of the UK Clinical Practice Research Datalink to detect neurodevelopmental effects of medicine exposure in utero: comparative analysis of an antiepileptic drug exposed cohort

Charlton, R., McGrogan, A., Snowball, J., Yates, L., Wood, A., Clayton-Smith, J., Smithson, H., Richardson, J., McHugh, N., Thomas, S., Bromley, R. & Baker, G., 2017, In: Drug Safety. p. 1–11

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate

Bromley, R., Calderbank, R., Cheyne, C. P., Rooney, C., Trayner, P., Clayton-Smith, J., García-Fiñana, M., Irwin, B., Morrow, J., Shallcross, R. & Baker, G., 2016, In: Neurology. 87, 18, p. 1943-1953

Research output: Contribution to journal › Article › peer-review

Open Access

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The treatment of epilepsy in pregnancy: The neurodevelopmental risks associated with exposure to antiepileptic drugs

Bromley, R., Sept 2016, In: Reproductive Toxicology. 64, p. 203-10

Research output: Contribution to journal › Article › peer-review

Open Access

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2015

Does in-utero exposure of antiepileptic drugs lead to failure to reach full cognitive potential?

McCorry, D. & Bromley, R., 2015, In: Seizure - European Journal of Epilepsy. 28, p. 51-56 5 p.

Research output: Contribution to journal › Article › peer-review

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. A controlled cohort study

Baker, G. A., Bromley, R. L., Briggs, M., Cheyne, C. P., Cohen, M. J., García-Fiñana, M., Gummery, A., Kneen, R., Loring, D. W., Mawer, G., Meador, K. J., Shallcross, R. & Clayton-Smith, J., 27 Jan 2015, In: Neurology. 84, 4, p. 382-390 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2014

Breastfeeding in children of women taking antiepileptic drugs: Cognitive outcomes at age 6 years

Meador, K. J., Baker, G. A., Browning, N., Cohen, M. J., Bromley, R. L., Clayton-Smith, J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M. & Loring, D. W., Aug 2014, In: JAMA pediatrics. 168, 8, p. 729-736 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

In utero exposure to levetiracetam vs valproate: development and language at 3 years of age.

Shallcross, R., Bromley, R. L., Cheyne, C. P., García-Fiñana, M., Irwin, B., Morrow, J. & Baker, G. A., 21 Jan 2014, In: Neurology. 82, 3, p. 213-221 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child

Bromley, R., Weston, J., Adab, N., Greenhalgh, J., Sanniti, A., McKay, A. J., Smith, C. T. & Marson, A. G., 27 Oct 2014, In: Cochrane Database of Systematic Reviews. 10, Art. No.: CD010236.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): A prospective observational study

Meador, K. J., Baker, G. A., Browning, N., Cohen, M. J., Bromley, R. L., Clayton-Smith, J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M. & Loring, D. W., Mar 2013, In: The Lancet Neurology. 12, 3, p. 244-252 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs

Bromley, R. L., Mawer, G. E., Briggs, M., Cheyne, C., Clayton-Smith, J., García-Fiñana, M., Kneen, R., Lucas, S. B., Shallcross, R., Baker, G. A., Dixon, P. (Collaborator), Fryer, A. (Collaborator), Gummery, A. (Collaborator) & Kerr, L. (Collaborator), Jun 2013, In: Journal of Neurology, Neurosurgery and Psychiatry. 84, 6, p. 637-643 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2012

Effects of fetal antiepileptic drug exposure: Outcomes at age 4.5 years

Meador, K. J., Baker, G. A., Browning, N., Cohen, M. J., Bromley, R. L., Clayton-Smith, J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M. & Loring, D. W., 17 Apr 2012, In: Neurology. 78, 16, p. 1207-1214 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Fetal effects of selective serotonin reuptake inhibitor treatment during pregnancy: Immediate and longer term child outcomes

Bromley, R. L., Wieck, A., Makarova, D., Tower, C., Wood, A. & Clayton-Smith, J., Nov 2012, In: Fetal and Maternal Medicine Review. 23, 3-4, p. 230-275 45 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2011

Child development following in utero exposure: levetiracetam vs sodium valproate.

Shallcross, R., Bromley, R. L., Irwin, B., Bonnett, L. J., Morrow, J., Baker, G. A., Fryer, A. (Collaborator), Kneen, R. (Collaborator), Banka, S. (Collaborator), Briggs, M. (Collaborator), Clayton-Smith, J. (Collaborator), Mawer, G. (Collaborator), Baker, G. (Collaborator), Bromley, R. (Collaborator), Dixon, P. (Collaborator), Gummery, A. (Collaborator), Shallcross, R. (Collaborator), Kerr, L. (Collaborator), Craig, J. (Collaborator) & Hunt, S. (Collaborator) & 9 others, Irwin, B. (Collaborator), Morrison, P. (Collaborator), Morrow, J. (Collaborator), Delanty, N. (Collaborator), Liggan, B. (Collaborator), Russell, A. (Collaborator), Smithson, H. (Collaborator), Parsons, L. (Collaborator) & Robertson, I. (Collaborator), 25 Jan 2011, In: Neurology. 76, 4, p. 383-389 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Cognitive and neurodevelopmental effects of antiepileptic drugs

Bromley, R. L., Leeman, B. A., Baker, G. A. & Meador, K. J., Sept 2011, In: Epilepsy and Behavior. 22, 1, p. 9-16 7 p.

Research output: Contribution to journal › Article › peer-review

Fetal antiepileptic drug exposure: Motor, adaptive, and emotional/behavioral functioning at age 3 years

Cohen, M. J., Meador, K. J., Browning, N., Baker, G. A., Clayton-Smith, J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M., Loring, D. W. & Bromley, R., Oct 2011, In: Epilepsy and Behavior. 22, 2, p. 240-246 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age

Meador, K. J., Baker, G. A., Browning, N., Cohen, M. J., Clayton-Smith, J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M., Loring, D. W. & Bromley, R., Feb 2011, In: Brain. 134, 2, p. 396-404 8 p.

Research output: Contribution to journal › Article › peer-review

Relationship of child IQ to parental IQ and education in children with fetal antiepileptic drug exposure

Meador, K. J., Baker, G. A., Browning, N., Clayton-Smith, J., Cohen, M. J., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M., Loring, D. W. & Bromley, R., Jun 2011, In: Epilepsy and Behavior. 21, 2, p. 147-152 5 p.

Research output: Contribution to journal › Article › peer-review

2010

Early cognitive development in children born to women with epilepsy: A prospective report

Bromley, R. L., Mawer, G., Love, J., Kelly, J., Purdy, L., McEwan, L., Briggs, M., Smith, J. C., Sin, X., Banka, S. & Baker, G. A., Oct 2010, In: Epilepsia. 51, 10, p. 2058-2065 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Pregnancy with epilepsy: Obstetric and neonatal outcome of a controlled study

Mawer, G., Briggs, M., Baker, G. A., Bromley, R., Coyle, H., Eatock, J., Kerr, L., Kini, U., Kuzmyshcheva, L., Lucas, S. B., Wyatt, L., Clayton-Smith, J. & Banka, S., Mar 2010, In: Seizure: European Journal of Epilepsy. 19, 2, p. 112-119 7 p.

Research output: Contribution to journal › Article › peer-review

2009

Cognitive abilities and behaviour of children exposed to antiepileptic drugs in utero

Bromley, R. L., Baker, G. A. & Meador, K. J., Apr 2009, In: Current Opinion in Neurology. 22, 2, p. 162-166 4 p.

Research output: Contribution to journal › Article › peer-review

Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs

Meador, K. J., Baker, G. A., Browning, N., Clayton-Smith, J., Combs-Cantrell, D. T., Cohen, M., Kalayjian, L. A., Kanner, A., Liporace, J. D., Pennell, P. B., Privitera, M., Loring, D. W. & Bromley, R., 16 Apr 2009, In: New England Journal Of Medicine. 360, 16, p. 1597-1605 8 p.

Research output: Contribution to journal › Article › peer-review

The behavioral consequences of exposure to antiepileptic drugs in utero

Clayton-Smith, J., Vinten, J., Bromley, R. L., Taylor, J., Adab, N., Kini, U. & Baker, G. A., Jan 2009, In: Epilepsy and Behavior. 14, 1, p. 197-201 4 p.

Research output: Contribution to journal › Article › peer-review

Rebecca Bromley, ClinPsyD, PhD

Research output

Search results