Rosanna Wright

2024

A chromosomal mutation is superior to a plasmid-encoded mutation for plasmid fitness cost compensation

Wright, R. C. T., Wood, A. J., Bottery, M. J., Muddiman, K. J., Paterson, S., Harrison, E., Brockhurst, M. A., Hall, J. P. J. & de Visser, J. A. G. M. (Editor), 2 Dec 2024, In: PLoS Biology. 22, 12, e3002926.

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Exploiting lung adaptation and phage steering to clear pan-resistant Pseudomonas aeruginosa infections in vivo

Ashworth, E., Wright, R., Shears, R., Wong, J., Hassan, A., Hall, J., Kadioglu, A. & Fothergill, J., 20 Feb 2024, In: Nature Communications. 15, 1, 1547.

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Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits

Buddle, J. E., Thompson, L. M., Williams, A. S., Wright, R. C. T., Durham, W. M., Turner, C. E., Chaudhuri, R. R., Brockhurst, M. A. & Fagan, R. P., 15 Aug 2024, In: PLoS Biology. 22, 8, e3002741.

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Multi-layered genome defences in bacteria

Agapov, A., Baker, K. S., Bedekar, P., Bhatia, R. P., Blower, T. R., Brockhurst, M. A., Brown, C., Chong, C. E., Fothergill, J. L., Graham, S., Hall, J. P., Maestri, A., Mcquarrie, S., Olina, A., Pagliara, S., Recker, M., Richmond, A., Shaw, S. J., Szczelkun, M. D. & Taylor, T. B. & 5 others, Van houte, S., Went, S. C., Westra, E. R., White, M. F. & Wright, R., 1 Apr 2024, In: Current Opinion in Microbiology. 78, 102436.

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2023

The novel anti-phage system Shield co-opts an RmuC domain to mediate phage defense across Pseudomonas species

Macdonald, E., Wright, R., Connolly, J. P. R., Strahl, H., Brockhurst, M., Van houte, S., Blower, T. R., Palmer, T., Mariano, G. & Matic, I. (Editor), 5 Jun 2023, In: PLoS Genetics. 19, 6, p. e1010784 e1010784.

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2021

Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

Hall, J. P. J., Wright, R. C. T., Harrison, E., Muddiman, K. J., Wood, A. J., Paterson, S., Brockhurst, M. A. & De Visser, J. A. G. M., 13 Oct 2021, In: PLoS Biology. 19, 10, p. e3001225

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2020

Eco-evolutionary dynamics set the tempo and trajectory of metabolic evolution in multispecies communities

Evans, R., Beckerman, A. P., Wright, R., McQueen-Mason, S. J., Brockhurst, M. & Bruce, N. C., 4 Sept 2020, (Accepted/In press) In: Current biology .

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2019

Resistance evolution against phage combinations depends on the timing and order of exposure

Wright, R. C. T., Friman, V. P., Smith, M. C. M. & Brockhurst, M. A., 24 Sept 2019, In: mBio. 10, 5, e01652-19.

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Temperate Bacteriophages from Chronic Pseudomonas aeruginosa Lung Infections Show Disease-Specific Changes in Host Range and Modulate Antimicrobial Susceptibility

Tariq, M. A., Everest, F. L. C., Cowley, L. A., Wright, R., Holt, G. S., Ingram, H., Duignan, L. A. M., Nelson, A., Lanyon, C. V., Perry, A., Perry, J. D., Bourke, S., Brockhurst, M. A., Bridge, S. H., De Soyza, A. & Smith, D. L., Jul 2019, In: mSystems. 4, 4, e00191-18.

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