Research output per year
Research output per year
- 39 results
Search results
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2022
Cardiomyocyte-specific loss of plasma membrane calcium ATPase 1 impacts cardiac rhythm and is associated with ventricular repolarisation dysfunction
Wilson, C., Stafford, N., Zi, M., Chelu, A., Niort, B. C., Li, Y., Baudoin, F., Prehar, S., Trafford, A. W. & Cartwright, E. J., 1 Aug 2022, In: Journal of molecular and cellular cardiology.Research output: Contribution to journal › Article › peer-review
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Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes
Rajab, B., Kassab, S., Mironov, A., Stonall, C., Daghistani, H., Gibbons, S., Mamas, M., Smith, D., Albalawi, Z., Baudoin, F., Zi, M., Prehar, S., Cartwright, E., Zhang, Y. H. & Kitmitto, A., 19 Jan 2022, In: Scientific Reports. 12, 1, 978.Research output: Contribution to journal › Article › peer-review
Open Access -
Microrna-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice
Nugroho, A., Stafford, N., Zi, M., Prehar, S., Potter, R., Kwon, D., Kohar, Y., Triastuti, E. & Anh Bu, T., 2022, In: JACC: Basic to Translational Science.Research output: Contribution to journal › Article › peer-review
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2021
PMCA4 inhibition does not affect cardiac remodelling following myocardial infarction, but may reduce susceptibility to arrythmia
Prehar, S., 15 Jan 2021, In: Scientific Reports. 11, 1518.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming
Baxter, M., Voronkov, M., Poolman, T., Galli, G., Pinali, C., Goosey, L., Knight, A., Krakowiak, K., Maidstone, R., Iqbal, M., Zi, M., Prehar, S., Cartwright, E. J., Gibbs, J., Matthews, L. C., Adamson, A. D., Humphreys, N. E., Rebelo-guiomar, P., Minczuk, M., Bechtold, D. A., & 2 others, 15 Jan 2020, In: eLife. 9, e50705.Research output: Contribution to journal › Article › peer-review
Open Access -
Signaling via the Interleukin-10 Receptor Attenuates Cardiac Hypertrophy in Mice During Pressure Overload, but not Isoproterenol Infusion
Stafford, N., Assrafally, F., Prehar, S., Zi, M., De Morais, A. M., Maqsood, A., Cartwright, E., Mueller, W. & Oceandy, D., 30 Oct 2020, (E-pub ahead of print) In: Frontiers in Pharmacology.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains
Zi, M., Stafford, N., Prehar, S., Baudoin, F., Oceandy, D., Wang, X., Bui, T., Shaheen, M., Neyses, L. & Cartwright, E., 1 Dec 2019, In: Current Research in Physiology.Research output: Contribution to journal › Article › peer-review
Open Access -
Pharmacological Inhibition of Hippo Pathway using XMU‐MP‐1 Protects The Heart Against Adverse Effects during Pressure Overload
Triastuti, E., Nugroho, A. B., Zi, M., Prehar, S., Kohar, Y. S., Bui, T. A., Stafford, N., Cartwright, E. J., Abraham, S. & Oceandy, D., 2019, In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Acute inhibition of PMCA4, but not global ablation, reduces blood pressure and arterial contractility via a nNOS-dependent mechanism
Lewis, S., Little, R., Baudoin, F., Prehar, S., Neyses, L., Cartwright, E. & Austin, C., 2017, In: Journal of cellular and molecular medicine.Research output: Contribution to journal › Article › peer-review
Open Access -
An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility
Lessard, S., Stern Gatof, E., Beaudoin, M., Schupp, P. G., Sher, F., Prehar, S., Ali, S. A., Kurita, R., Nakamura, Y., Baena Chaparro, E., Ledoux, J., Oceandy, D., Bauer, D. & Lettre, G., 1 Aug 2017, In: Journal of Clinical Investigation. 127, 8, p. 3065-3074 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile128 Downloads (Pure) -
Reduced Expression of PMCA1 is Associated with Increased Blood Pressure with Age Which is Preceded by Remodeling of Resistance Arteries
Little, R., Zi, M., Hammad, S. K., Nguyen, L., Njegic, A., Kurusamy, S., Prehar, S., Armesilla, A. L., Neyses, L., Austin, C. & Cartwright, E., 2017, In: Aging cell. 16, 5Research output: Contribution to journal › Article › peer-review
Open Access -
Stress-Activated Kinase MKK7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention
Chowdhury, S. K., Liu, W., Zi, M., Li, Y., Wang, S., Tsui, H., Prehar, S., Castro, S., Zhang, H., Ji, Y., Zhang, X., Xiao, R., Zhang, R., Lei, M., Cyganek, L., Guan, K., Millar, C. B., Liao, X., Jain, M. K., Boyett, M. R., & 3 others, 2017, In: Circulation. 135, 7, p. 683-699 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile117 Downloads (Pure) -
2016
Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?
van Loon, E. P. M., Little, R., Prehar, S., Bindels, R. J. M., Cartwright, E. J. & Hoenderop, J. G. J., 21 Apr 2016, In: PLoS ONE. 11, 4, e0153483.Research output: Contribution to journal › Article › peer-review
Open Access -
The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice
Omede, A., Zi, M., Prehar, S., Maqsood, A., Stafford, N., Mamas, M., Cartwright, E. & Oceandy, D., 2016, In: Biochemical and Biophysical Research Communications. 479, 4, p. 708-714 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile176 Downloads (Pure) -
The Plasma Membrane Calcium ATPase 4 Signalling in Cardiac Fibroblasts Mediates Cardiomyocyte Hypertrophy
Mohamed, T. M. A., Abou-Leisa, R., Stafford, N., Maqsood, A., Zi, M., Prehar, S., Baudoin, F., Wang, X., Neyses, L., Cartwright, E. & Oceandy, D., 29 Mar 2016, In: Nature Communications. 7:1107, 11074.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32.
Tsui, H., Zi, M., Wang, S., Chowdhury, S. K., Prehar, S., Liang, Q., Cartwright, E. J., Lei, M., Liu, W. & Wang, X., Dec 2015, In: Hypertension. 66, 6, p. 1176-1183 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile121 Downloads (Pure) -
2014
Ablation of the Hypertension Candidate Gene ATP2B1 Results in Increased Blood Pressure and Cardiac Hypertrophic Remodeling. American Heart Association Scientific Sessions 2014-Abstract 13798
Hammad, S. K., Zi, M., Prehar, S., Little, R., Neyses, L. & Cartwright, E., 2014, In: Circulation. 130, Suppl 2Research output: Contribution to journal › Article › peer-review
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Exercise training reduces resting heart rate via downregulation of the funny channel HCN4
D'souza, A., Bucchi, A., Johnsen, A. B., Logantha, S. J. R. J., Monfredi, O., Yanni, J., Prehar, S., Hart, G., Cartwright, E., Wisloff, U., Dobrzynski, H., Difrancesco, D., Morris, G. M. & Boyett, M. R., 13 May 2014, In: Nature Communications. 5, 3775.Research output: Contribution to journal › Article › peer-review
Open Access -
Global PMCA1 deletion leads to increased blood pressure and left ventricular hypertrophy. The Heart Failure Congress 2014-Rapid Fire-Basic Science 1-Abstract 520
Hammad, S., Zi, M., Prehar, S., Neyses, L. & Cartwright, E., 2014, In: European Journal of Heart failure. 16, s2, p. 108-112 5 p.Research output: Contribution to journal › Article › peer-review
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Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction
Ulm, S., Liu, W., Zi, M., Tsui, H., Chowdhury, S. K., Endo, S., Satoh, Y., Prehar, S., Wang, R., Cartwright, E. J. & Wang, X., 13 Mar 2014, In: Journal of molecular and cellular cardiology. 72, p. 104-116 12 p.Research output: Contribution to journal › Article › peer-review
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Targeted deletion of the Extracellular Signal-Regulated Protein Kinase 2 (ERK2) attenuates hypertrophic response in the heart
Ulm, S., Zi, M., Liu, W., Tsui, H., Chowdhury, S. K., Jin, J., Prehar, S., Neyses, L., Lei, M., Cartwright, E. & Wang, X., Jul 2014, In: Journal of molecular and cellular cardiology. 72, p. 104-116 12 p.Research output: Contribution to journal › Article › peer-review
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The mammalian Ste20-like kinase 2 (Mst2) modulates stress-induced cardiac hypertrophy
Zi, M., Maqsood, A., Prehar, S., Mohamed, T. M. A., Abou-Leisa, R., Robertson, A., Cartwright, E. J., Ray, S. G., Oh, S., Lim, D. S., Neyses, L. & Oceandy, D., 2014, In: Journal of Biological Chemistry. 289, 35, p. 24275-24288 13 p.Research output: Contribution to journal › Article › peer-review
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The tumour suppressor Ras-association domain family protein 1A (RASSF1A) regulates TNF-α signalling in cardiomyocytes
Mohamed, T. M. A., Zi, M., Prehar, S., Maqsood, A., Abou-Leisa, R., Nguyen, L., Pfeifer, G. P., Cartwright, E. J., Neyses, L. & Oceandy, D., 1 Jul 2014, In: Cardiovascular research. 103, 1, p. 47-59 12 p.Research output: Contribution to journal › Article › peer-review
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YIA2 PMCA1 Deletion Leads to Increased Blood Pressure and Cardiac Hypertrophy.
Hammad, S., Zi, M., Prehar, S., Neyses, L. & Cartwright, E., Jun 2014, In: Heart (British Cardiac Society). 100, Suppl 3Research output: Contribution to journal › Article › peer-review
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2013
A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin
Liu, W., Zi, M., Tsui, H., Chowdhury, S. K., Zeef, L., Meng, Q. J., Travis, M., Prehar, S., Berry, A., Hanley, N. A., Neyses, L., Xiao, R. P., Oceandy, D., Ke, Y., Solaro, R. J., Cartwright, E. J., Lei, M. & Wang, X., 10 Jun 2013, In: Circulation: Heart Failure. 6, 4, p. 833-844 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Downloads (Pure) -
2011
Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload
Liu, W., Zi, M., Chi, H., Jin, J., Prehar, S., Neyses, L., Cartwright, E. J., Flavell, R. A., Davis, R. J. & Wang, X., Apr 2011, In: Journal of molecular and cellular cardiology. 50, 4, p. 702-711 9 p.Research output: Contribution to journal › Article › peer-review
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Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.
Zi, M., Kimura, T., Liu, W., Jin, J., Higham, N. J., Kharche, S., Hao, G., Shi, Y., Shen, W., Prehar, S., Mironov, A., Neyses, L., Bierhuizen, MF., Boyett, M., Zhang, H., Lei, M., Cartwright, E. & Wang, X., 20 May 2011, In: The Journal of biological chemistry. 286, 20, p. 17821-17830 9 p.Research output: Contribution to journal › Article › peer-review
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Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart
Liu, W., Zi, M., Naumann, R., Ulm, S., Jin, J., Taglieri, D. M., Prehar, S., Gui, J., Tsui, H., Xiao, R. P., Neyses, L., Solaro, R. J., Ke, Y., Cartwright, E. J., Lei, M. & Wang, X., 13 Dec 2011, In: Circulation. 124, 24, p. 2702-2715 13 p.Research output: Contribution to journal › Article › peer-review
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Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain
Mohamed, T. M. A., Oceandy, D., Zi, M., Prehar, S., Alatwi, N., Wang, Y., Shaheen, M. A., Abou-Leisa, R., Schelcher, C., Hegab, Z., Baudoin, F., Emerson, M., Mamas, M., Di Benedetto, G., Zaccolo, M., Lei, M., Cartwright, E. J. & Neyses, L., 2 Dec 2011, In: Journal of Biological Chemistry. 286, 48, p. 41520-41529 9 p.Research output: Contribution to journal › Article › peer-review
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2010
Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart
Kimura, T., Jin, J., Zi, M., Prehar, S., Liu, W., Oceandy, D., Abe, J. I., Neyses, L., Weston, A. H., Cartwright, E. J. & Wang, X., 19 Mar 2010, In: Circulation research. 106, 5, p. 961-970 9 p.Research output: Contribution to journal › Article › peer-review
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2009
Cardiac-specific deletion of Mkk4 reveals its role in pathological hypertrophic remodeling but not in physiological cardiac growth
Liu, W., Zi, M., Jin, J., Prehar, S., Oceandy, D., Kimura, T. E., Lei, M., Neyses, L., Weston, A. H., Cartwright, E. J. & Wang, X., 10 Apr 2009, In: Circulation research. 104, 7, p. 905-914 9 p.Research output: Contribution to journal › Article › peer-review
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EuroPhenome: A repository for high-throughput mouse phenotyping data
Morgan, H., Beck, T., Blake, A., Gates, H., Adams, N., Debouzy, G., Leblanc, S., Lengger, C., Maier, H., Melvin, D., Meziane, H., Richardson, D., Wells, S., White, J., Wood, J., De Angelis, M. H., Brown, S. D. M., Hancock, J. M., Mallon, A. M., Neyses, L., & 4 others, 23 Nov 2009, In: Nucleic acids research.. 38, 1, p. D577-D585Research output: Contribution to journal › Article › peer-review
Open Access -
Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the β-adrenergic signal in the myocardium
Mohamed, T. M. A., Oceandy, D., Prehar, S., Alatwi, N., Hegab, Z., Baudoin, F. M., Pickard, A., Zaki, A. O., Nadif, R., Cartwright, E. J. & Neyses, L., 1 May 2009, In: Journal of Biological Chemistry. 284, 18, p. 12091-12098 7 p.Research output: Contribution to journal › Article › peer-review
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The cardiovascular phenotype of a mouse model of acromegaly
Izzard, A. S., Emerson, M., Prehar, S., Neyses, L., Trainer, P., List, E. O., Kopchick, J. J. & Heagerty, A. M., Oct 2009, In: Growth Hormone and IGF Research. 19, 5, p. 413-419 6 p.Research output: Contribution to journal › Article › peer-review
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Tumor suppressor ras-association domain family 1 Isoform A Is a novel regulator of cardiac hypertrophy
Oceandy, D., Pickard, A., Prehar, S., Zi, M., Mohamed, T. M. A., Stanley, P. J., Baudoin-Stanley, F., Nadif, R., Tommasi, S., Pfeifer, G. P., Armesilla, A. L., Cartwright, E. J. & Neyses, L., 18 Aug 2009, In: Circulation. 120, 7, p. 607-616 9 p.Research output: Contribution to journal › Article › peer-review
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2007
Neuronal nitric oxide synthase signaling in the heart is regulated by the sarcolemmal calcium pump 4b
Oceandy, D., Cartwright, E. J., Emerson, M., Prehar, S., Baudoin, F. M., Zi, M., Alatwi, N., Venetucci, L., Schuh, K., Williams, J. C., Armesilla, A. L. & Neyses, L., Jan 2007, In: Circulation. 115, 4, p. 483-492 9 p.Research output: Contribution to journal › Article › peer-review
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2003
Interleukin-6 is an afferent signal to the hypothalamo-pituitary-adrenal axis during local inflammation in mice
Turnbull, A. V., Prehar, S., Kennedy, A. R., Little, R. A. & Hopkins, S. J., 1 May 2003, In: Endocrinology. 144, 5, p. 1894-1906 12 p.Research output: Contribution to journal › Article › peer-review
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1991
Autoradiographic localization of [125I]Endothelin binding sites in human blood vessels and coronary tissue: Functional correlates
Dashwood, M. R., Sykes, R. M., Muddle, J. R., Collins, M. J., Prehar, S., Theodoropoulos, S. & Yacoub, M. H., 1991, In: Journal of Cardiovascular Pharmacology. 17, 7, p. S458-S462Research output: Contribution to journal › Article › peer-review
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Identification of [(125)I]endothelin binding sites in human coronary tissue.
Dashwood, M. R., Sykes, R. M., Collins, M. J., Prehar, S., Theodoropoulos, S. & Yacoub, M. H., 1991, In: Neurochemistry International: the journal of cellular and molecular neuroscience . 18, 4Research output: Contribution to journal › Article › peer-review