Research output per year
Research output per year
Personal profile
Biography
2004 - 2007 Post Doctoral Fellow, Cancer Research UK London Research Institute, London
2007 - 2010 Post Doctoral Fellow, Institute of Cancer Research, London
2011 - 2014 Senior Research Associate, University College London
2014 - Lecturer, University of Manchester
Qualifications
Ph.D 2004, Biochemistry, University of Cologne, Germany
M.Sc. 1999, Medical Biochemistry, Mahatma Gandhi University, Kerala, India.
B.Sc. 1996, Mahatma Gandhi University, Kerala, India.
Research interests
Understanding the mechanisms of blood vessel development have implications in a number of human disease conditions such as cardiovascular disease, eye disease and cancer where abnormal vessel growth plays a crucial part in the pathogenesis. Insights in the cellular signalling pathways regulating angiogenesis are essential for designing novel therapeutic strategies. We are particularly interested in investigating a secreted small ligand called apelin and its role in diabetic retinopathy using mouse as the model system.
Memberships of committees and professional bodies
ARVO - The Association for Research in Vision and Ophthalmology
NAVBO - North American VAscular Biology Organisation
My group
Present and Past Lab Members
Ms. Karen Tzia Wei Lim PhD Student 2016-2020 ( Co-supervising with Prof. Clair Baldock)
Ms. Shona Borland PhD Student 2017-2020 ( Co-Supervising with Prof. Bernard Keavney)
Ms. Efta Triastuti PhD Student 2017- 2020( Co-supervising with Dr. Delvac Oceandy)
Mr David Scannali PhD Student 2019-2023 ( Supervising with Dr. Nick Ashton and Prof. Maciej Tomaszewski
Mr.Daniel Mcmanus Final year undergraduate project 2020
Ms Sareeka Yadav MRes in Cardiovascular Science project 2020
Ms. Rebecca Horsfall Research Technician 2015
Ms. Alexandra Njegic 2015 BHF PhD rotation student
Mr. Daniel Prescott 2016 MRes in Cardiovascular Science
Ms. Héloïse Grunchec 2015 MSc Summer student
Mr. Sanjay Goorwappa 2017 Medical student (APEP project)
Mr. Harry Charalambos 2017 Medical student (APEP project)
Mr. Brandon Yeo 2018 Medical student (APEP project)
Mr. Kieran Hardy 2018 Masters in Molecular Medicine
Ms Wai Chun Tse 2019 MSc Clinical Biochemistry
Teaching
MRes Cardiovascular Health and Disease
PEP/APEP Supervisor for Mancheser Medical School
PBL Tutor for MBChB
BSc Biomedical Sciences
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Human Cardiac Organoids: Quantification and Qualification in Cardiovascular Studies
Liu, Y., Abraham, S. & Xu, H., 29 Aug 2024, In: International Journal of Drug Discovery and Pharmacology.Research output: Contribution to journal › Article › peer-review
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Atrial Septal Defect (ASD) associated long non-coding RNA STX18-AS1 maintains time-course of in vitro cardiomyocyte differentiation
Liu, Y., Choy, M.-K., Abraham, S., Tenin, G., Black, G. C. & Keavney, B. D., 8 Aug 2022, In: Genes & Diseases.Research output: Contribution to journal › Article › peer-review
Open Access -
Data on cardiac lncRNA STX18-AS1 expression in developing human hearts and function during in vitro hESC-cardiomyocyte differentiation
Liu, Y., Choy, M.-K., Abraham, S., Tenin, G., Black, G. C. & Keavney, B. D., Dec 2022, In: Data in Brief. 45, p. 108770Research output: Contribution to journal › Article › peer-review
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Progress of 3D Organoid Technology for Preclinical Investigations: Towards Human In Vitro Models
Liu, Y., Xu, H., Abraham, S., Wang, X. & Keavney, B. D., 21 Dec 2022, In: International Journal of Drug Discovery and Pharmacology. 1, 9 p.Research output: Contribution to journal › Review article › peer-review
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Investigating the role of KMT2C in heart development
Borland, S. C., Tenin, G., Monaghan, R., Williams, S., Zi, M., Wilson, C., Prehar, S., Cartwright, E., Abraham, S. & Keavney, B., Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 42-42 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
Projects
- 3 Finished
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BHF 4-Year PhD Studentship - University of Manchester (3rd Intake 2019 of 4th Scheme).
Cartwright, E. (PI), Abraham, S. (CoI), Allan, S. (CoI), Ashton, N. (CoI), Ballestrem, C. (CoI), Dibb, K. (CoI), Dobrzynski, H. (CoI), Eisner, D. (CoI), Galli, G. (CoI), Greenstein, A. (CoI), Heagerty, A. (CoI), Hentges, K. (CoI), Herbert, S. (CoI), Keavney, B. (CoI), Kitmitto, A. (CoI), Liu, W. (CoI), Oceandy, D. (CoI), Pinali, C. (CoI), Pinteaux, E. (CoI), Saiani, A. (CoI), Shiels, H. (CoI), Talavera, D. (CoI), Tomaszewski, M. (CoI), Trafford, A. (CoI), Venetucci, L. (CoI) & Wang, X. (CoI)
1/10/19 → 30/09/23
Project: Research
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BHF 4yr PhD Studentship - 2018 Intake.
Cartwright, E. (PI), Abraham, S. (CoI), Allan, S. (CoI), Ashton, N. (CoI), Ballestrem, C. (CoI), Boyett, M. (CoI), Dibb, K. (CoI), Dobrzynski, H. (CoI), Eisner, D. (CoI), Galli, G. (CoI), Greenstein, A. (CoI), Heagerty, A. (CoI), Hentges, K. (CoI), Herbert, S. (CoI), Keavney, B. (CoI), Kitmitto, A. (CoI), Liu, W. (CoI), Miller, C. (CoI), Oceandy, D. (CoI), Parry-Jones, A. (CoI), Saiani, A. (CoI), Sherratt, M. (CoI), Shiels, H. (CoI), Talavera, D. (CoI), Tomaszewski, M. (CoI), Trafford, A. (CoI), Venetucci, L. (CoI) & Wang, X. (CoI)
1/10/18 → 30/09/22
Project: Research
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BHF 4-Year PhD Studentship Award - University of Manchester (1st Intake 2017 of 4th Scheme).
Cartwright, E. (PI), Abraham, S. (CoI), Allan, S. (CoI), Ballestrem, C. (CoI), Boyett, M. (CoI), Canfield, A. (CoI), Dibb, K. (CoI), Dobrzynski, H. (CoI), Eisner, D. (CoI), Galli, G. (CoI), Heagerty, A. (CoI), Hentges, K. (CoI), Herbert, S. (CoI), Holt, C. (CoI), Humphries, M. (CoI), Keavney, B. (CoI), Kitmitto, A. (CoI), Liu, W. (CoI), Miller, C. (CoI), Oceandy, D. (CoI), Parry-Jones, A. (CoI), Saiani, A. (CoI), Sherratt, M. (CoI), Shiels, H. (CoI), Talavera, D. (CoI), Tomaszewski, M. (CoI), Trafford, A. (CoI), Venetucci, L. (CoI), Wang, X. (CoI) & Zhang, Y. (CoI)
1/10/17 → 30/09/21
Project: Research