Research output per year
Research output per year
Personal profile
Overview
Research in Medicinal Chemistry.
Lead for Social Responsibility in Division of Pharmacy & Optometry
Memberships of committees and professional bodies
- Fellow of the Royal Society of Chemistry, FRSC
- Member of The Lister Institute
Research interests
Dr Sally Freeman is interested in the fields of inositol phosphate chemistry, design and synthesis of drugs for the treatment of cancer, malaria, inflammation, Alzheimer's disease, epilepsy and genetic eye disorders.
Teaching
Chair of PIAT Exam Board.
Academic Lead for PASS.
Unit lead for first year MPharm Medicine (PHAR10100).
Biography
Sally Freeman is a Reader in organic/medicinal chemistry. Following her PhD in 1985 she was awarded an SERC-NATO Postdoctoral Fellowship at the Chemistry Department, Harvard University, under the supervision of Prof Jeremy Knowles. In 1987 she returned to the UK to take up a lectureship in the School of Pharmacy, Aston University. In 1989 she was awarded a 5.5 year Lister Fellowship. Prior to moving to the University of Manchester in 1994, Sally spent 6 months as a Visiting Research-Scientist at Arizona State University. Sally was promoted to Senior Lecturer in 1997 and Reader in 2009.
Qualifications
1982 - BSc(Hons) Chemistry - First Class (Dunlop Polymer Prize) - University of Leicester
1985 - PhD Organophosphorus Chemistry - University of Leicester
1993 - Lilly Prize for Pharmaceutical Excellence
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Fingerprint
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- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Carvedilol Analogue, VKII-86, Prevents Hypokalaemia- induced Ventricular Arrhythmia through Novel multi-Channel Effects.
Freeman, S., Venetucci, L. & Robinson, V., 5 May 2022, In: British Journal of Pharmacology . 179, 11, p. 2713-2732 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules
Elhemely, M., Belgath, A., El Sayed, S., Burusco-Goni, K., Kadirvel, M., Tirella, A., Finegan, K., Bryce, R., Stratford, I. & Freeman, S., 15 Mar 2022, In: Journal of Medicinal Chemistry. 65, 6, p. 4783-4797Research output: Contribution to journal › Article › peer-review
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A selective Review and Virtual Screening Analysis of Natural Product Inhibitors of the NLRP3 Inflammasome
El Sayed, S., Freeman, S. & Bryce, R. A., 21 Sep 2022, In: Molecules.Research output: Contribution to journal › Review article › peer-review
Open Access -
Computational investigation of mechanisms for pH modulation of human chloride channels
Elverson, K., Freeman, S., Manson, F. & Warwicker, J., 5 Oct 2022, (E-pub ahead of print) In: bioRxiv.Research output: Contribution to journal › Article
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Probing the effect of NEK7 and cofactor interactions on dynamics of NLRP3 monomer using molecular simulation
El Sayed, S., Freeman, S. & Bryce, R. A., 1 Oct 2022, In: Protein science. 31, 10Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Finished
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Identifying a New Drug Target for the Treatment of Alzheimer's Disease.
Brough, D., Allan, S., Freeman, S. & Lawrence, C.
18/09/17 → 17/09/20
Project: Research
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University of Leicester (External organisation)
Sally Freeman (Member)
2015 → 2017Activity: Membership › Membership of committee
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The Lister Institute of Preventative Medicine (External organisation)
Sally Freeman (Member)
2000 → …Activity: Membership › Membership of professional association
Datasets
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CCDC 670830: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Brandt, S. D. (Contributor), Nasima, S. (Contributor), Turvey, N. (Contributor), Alder, J. F. (Contributor), Freeman, S. (Contributor) & Schwalbe, C. H. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/ccqj1py, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqj1py&sid=DataCite
Dataset
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CCDC 1563191: Experimental Crystal Structure Determination
Baldwin, A. (Contributor), Rivers-Auty, J. (Contributor), Daniels, M. (Contributor), White, C. (Contributor), Schwalbe, C. H. (Contributor), Schilling, T. (Contributor), Hammadi, H. (Contributor), Jaiyong, P. (Contributor), Spencer, N. G. (Contributor), England, H. (Contributor), Luheshi, N. M. (Contributor), Kadirvel, M. (Contributor), Lawrence, C. (Contributor), Rothwell, N. (Contributor), Harte, M. (Contributor), Bryce, R. (Contributor), Allan, S. M. (Contributor), Eder, C. (Contributor), Freeman, S. (Contributor) & Brough, D. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2017
DOI: 10.5517/ccdc.csd.cc1pgmj9, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1pgmj9&sid=DataCite
Dataset
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CCDC 690016: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Rattray, N. J. W. (Contributor), Etchells, L. L. (Contributor), Schwalbe, C. H. (Contributor), Blake, A. J. (Contributor), Bichenkova, E. (Contributor), Bryce, R. (Contributor), Barker, C. J. (Contributor), Díaz, A. (Contributor), Kremer, C. (Contributor) & Freeman, S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2009
DOI: 10.5517/ccr50lh, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccr50lh&sid=DataCite
Dataset
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CCDC 670831: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Brandt, S. D. (Contributor), Nasima, S. (Contributor), Turvey, N. (Contributor), Alder, J. F. (Contributor), Freeman, S. (Contributor) & Schwalbe, C. H. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/ccqj1qz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqj1qz&sid=DataCite
Dataset
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CCDC 1827704: Experimental Crystal Structure Determination
Alnabulsi, S. (Contributor), Hussein, B. H. K. (Contributor), Santina, E. (Contributor), Alsalahat, I. (Contributor), Kadirvel, M. (Contributor), Magwaza, R. (Contributor), Bryce, R. (Contributor), Schwalbe, C. H. (Contributor), Baldwin, A. (Contributor), Russo, I. (Contributor), Stratford, I. (Contributor) & Freeman, S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2018
DOI: 10.5517/ccdc.csd.cc1zbw6d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1zbw6d&sid=DataCite
Dataset