Research output per year
Research output per year
Personal profile
Overview
Research in Medicinal Chemistry.
Memberships of committees and professional bodies
- Fellow of the Royal Society of Chemistry, FRSC
- Member of The Lister Institute
Research interests
Dr Sally Freeman is interested in the fields of inositol phosphate chemistry, design and synthesis of drugs for the treatment of cancer, malaria, inflammation, Alzheimer's disease, epilepsy and genetic eye disorders.
Teaching
Unit lead for first year MPharm Semester 2 Unit (PHAR11002)
Biography
Sally Freeman is a Reader in organic/medicinal chemistry. Following her PhD in 1985 she was awarded an SERC-NATO Postdoctoral Fellowship at the Chemistry Department, Harvard University, under the supervision of Prof Jeremy Knowles. In 1987 she returned to the UK to take up a lectureship in the School of Pharmacy, Aston University. In 1989 she was awarded a 5.5 year Lister Fellowship. Prior to moving to the University of Manchester in 1994, Sally spent 6 months as a Visiting Research-Scientist at Arizona State University. Sally was promoted to Senior Lecturer in 1997 and Reader in 2009.
Qualifications
1982 - BSc(Hons) Chemistry - First Class (Dunlop Polymer Prize) - University of Leicester
1985 - PhD Organophosphorus Chemistry - University of Leicester
1993 - Lilly Prize for Pharmaceutical Excellence
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Fingerprint
Dive into the research topics where Sally Freeman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome
Mcmahon, E., El Sayed, S., Green, J., Hoyle, C., Fitzpatrick, L., Jones, E., Corrie, E., Kelly, R., Challinor, M., Freeman, S., Bryce, R., Lawrence, C. B., Brough, D. & Kasher, P., 16 Feb 2024, In: iScience. 27, 2, 108968.Research output: Contribution to journal › Article
Open Access -
Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome.
Green, J., El-Sharkawy, L., Roth, S., Zhu, J., Cao, J., Leach, A., Liesz, A., Freeman, S. & Brough, D., 19 May 2024, In: iScience. 26, 5, 106758.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of Potent Benzothiazole Inhibitors of Oxidoreductase NQO2, a Target for Inflammation and Cancer
Belgath, A. A., Emam, A. M., Taujanskas, J., Bryce, R. A., Freeman, S. & Stratford, I. J., 8 Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12025.Research output: Contribution to journal › Article › peer-review
Open Access -
Virtual screening-led design of inhibitor scaffolds for the NLRP3 inflammasome
El-Sayed, S., Mcmahon, E., Musleh, S., Freeman, S., Brough, D., Kasher, P. R. & Bryce, R. A., 22 Oct 2024, (E-pub ahead of print) In: Bioorganic Chemistry. 107909.Research output: Contribution to journal › Article › peer-review
Open Access -
Computational investigation of mechanisms for pH modulation of human chloride channels
Elverson, K., Freeman, S., Manson, F. & Warwicker, J., 30 Jul 2023, In: Molecules. 28, 15, 5753.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Finished
-
Identifying a New Drug Target for the Treatment of Alzheimer's Disease.
Brough, D. (PI), Allan, S. (CoI), Freeman, S. (CoI) & Lawrence, C. (CoI)
18/09/17 → 17/09/20
Project: Research
-
University of Leicester (External organisation)
Freeman, S. (Member)
2015 → 2017Activity: Membership › Membership of committee › Research
-
The Lister Institute of Preventative Medicine (External organisation)
Freeman, S. (Member)
2000 → …Activity: Membership › Membership of professional association › Research
Datasets
-
CCDC 690016: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Rattray, N. J. W. (Contributor), Etchells, L. L. (Contributor), Schwalbe, C. H. (Contributor), Blake, A. J. (Contributor), Bichenkova, E. (Contributor), Bryce, R. (Contributor), Barker, C. J. (Contributor), Díaz, A. (Contributor), Kremer, C. (Contributor) & Freeman, S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2009
DOI: 10.5517/ccr50lh, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccr50lh&sid=DataCite
Dataset
-
CCDC 670830: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Brandt, S. D. (Contributor), Nasima, S. (Contributor), Turvey, N. (Contributor), Alder, J. F. (Contributor), Freeman, S. (Contributor) & Schwalbe, C. H. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/ccqj1py, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqj1py&sid=DataCite
Dataset
-
CCDC 670831: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Brandt, S. D. (Contributor), Nasima, S. (Contributor), Turvey, N. (Contributor), Alder, J. F. (Contributor), Freeman, S. (Contributor) & Schwalbe, C. H. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/ccqj1qz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqj1qz&sid=DataCite
Dataset
-
CCDC 762395: Experimental Crystal Structure Determination
Mansell, D. (Contributor), Rattray, N. J. W. (Contributor), Etchells, L. L. (Contributor), Schwalbe, C. H. (Contributor), Blake, A. J. (Contributor), Torres, J. (Contributor), Kremer, C. (Contributor), Bichenkova, E. (Contributor), Barker, C. J. (Contributor) & Freeman, S. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010
DOI: 10.5517/cctlbd3, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cctlbd3&sid=DataCite
Dataset
-
CCDC 1563192: Experimental Crystal Structure Determination
Baldwin, A. (Contributor), Rivers-Auty, J. (Contributor), Daniels, M. (Contributor), White, C. (Contributor), Schwalbe, C. H. (Contributor), Schilling, T. (Contributor), Hammadi, H. (Contributor), Jaiyong, P. (Contributor), Spencer, N. G. (Contributor), England, H. (Contributor), Luheshi, N. M. (Contributor), Kadirvel, M. (Contributor), Lawrence, C. (Contributor), Rothwell, N. (Contributor), Harte, M. (Contributor), Bryce, R. (Contributor), Allan, S. M. (Contributor), Eder, C. (Contributor), Freeman, S. (Contributor) & Brough, D. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2017
DOI: 10.5517/ccdc.csd.cc1pgmkb, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1pgmkb&sid=DataCite
Dataset