Research output per year
Research output per year
- 1 - 50 out of 68 results
Search results
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2022
Nitric oxide favours tumour-promoting inflammation through mitochondria-dependent and -independent actions on macrophages
Drehmer, D., Mesquita Luiz, J. P., Hernandez, C. A. S., Alves-filho, J. C., Hussell, T., Townsend, P. A. & Moncada, S., 27 May 2022, In: Redox biology. p. 102350Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Inflammation, glucose, and vascular cell damage: The role of the pentose phosphate pathway
Peiró, C., Romacho, T., Azcutia, V., Villalobos, L., Fernández, E., Bolaños, J. P., Moncada, S. & Sánchez-Ferrer, C. F., 1 Jun 2016, In: Cardiovascular Diabetology. 15, 82.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival
Funes, J. M., Henderson, S., Kaufman, R., Flanagan, J. M., Robson, M., Pedley, B., Moncada, S. & Boshoff, C., 3 Feb 2014, In: Molecular Cancer. 13, 1, 20.Research output: Contribution to journal › Article › peer-review
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2013
I Lección Magistral Andrés Laguna. Metabolismo de la división celular: descubrimiento y perspectives
Translated title of the contribution :1st andrés laguna master lecture. Metabolism of cell division: Discovery and perspectives Research output: Contribution to journal › Article › peer-review
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2012
Fulfilling the metabolic requirements for cell proliferation
Moncada, S., Higgs, E. A. & Colombo, S. L., 15 Aug 2012, In: Biochemical Journal. 446, 1, p. 1-7 6 p.Research output: Contribution to journal › Article › peer-review
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2011
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
Colombo, S. L., Palacios-Callender, M., Frakich, N., Carcamo, S., Kovacs, I., Tudzarova, S. & Moncada, S., 27 Dec 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 52, p. 21069-21074 5 p.Research output: Contribution to journal › Article › peer-review
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Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle
Tudzarova, S., Colombo, S., Stoeber, K., Carcamo, S., Williams, G. & Moncada, S., 2011, In: Proc Natl Acad Sci U S A.. 108, p. 5278-5283Research output: Contribution to journal › Article › peer-review
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Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle
Tudzarova, S., Colombo, S. L., Stoeber, K., Carcamo, S., Williams, G. H. & Moncada, S., 29 Mar 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 13, p. 5278-5283 5 p.Research output: Contribution to journal › Article › peer-review
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2010
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes
Colombo, S. L., Palacios-Callender, M., Frakich, N., De Leon, J., Schmitt, C. A., Boorn, L., Davis, N. & Moncada, S., 2 Nov 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 44, p. 18868-18873 5 p.Research output: Contribution to journal › Article › peer-review
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E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
Almeida, A., Bolaños, J. P. & Moncada, S., 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 2, p. 738-741 3 p.Research output: Contribution to journal › Article › peer-review
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Glycolysis: a bioenergetic or a survival pathway?
Bolaños, J. P., Almeida, A. & Moncada, S., Mar 2010, In: Trends in Biochemical Sciences. 35, 3, p. 145-149 4 p.Research output: Contribution to journal › Article › peer-review
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Inactivation of nitric oxide by cytochrome c oxidase under steady-state oxygen conditions
Unitt, D. C., Hollis, V. S., Palacios-Callender, M., Frakich, N. & Moncada, S., Mar 2010, In: Biochimica et Biophysica Acta. Bioenergetics . 1797, 3, p. 371-377 6 p.Research output: Contribution to journal › Article › peer-review
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Mitochondria as pharmacological targets
Moncada, S., May 2010, In: British Journal of Pharmacology. 160, 2, p. 217-219 2 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide, cytochrome c oxidase, and the cellular response to hypoxia
Taylor, C. T. & Moncada, S., Apr 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 643-647 4 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation
De Palma, C., Falcone, S., Pisoni, S., Cipolat, S., Panzeri, C., Pambianco, S., Pisconti, A., Allevi, R., Bassi, M. T., Cossu, G., Pozzan, T., Moncada, S., Scorrano, L., Brunelli, S. & Clementi, E., Nov 2010, In: Cell Death and Differentiation. 17, 11, p. 1684-1696 12 p.Research output: Contribution to journal › Article › peer-review
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2009
AMPKalpha1 regulates the antioxidant status of vascular endothelial cells
Columbo, S. L. & Moncada, S., 2009, In: Biochem J.. 421, p. 163-169Research output: Contribution to journal › Article › peer-review
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AMPKα1 regulates the antioxidant status of vascular endothelial cells
Colombo, S. L. & Moncada, S., 15 Jul 2009, In: Biochemical Journal. 421, 2, p. 163-169 6 p.Research output: Contribution to journal › Article › peer-review
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Regulation of oxygen distribution in tissues by endothelial nitric oxide
Victor, V. M., Nuñez, C., D'Ocón, P., Taylor, C. T., Esplugues, J. V. & Moncada, S., 22 May 2009, In: Circulation research. 104, 10, p. 1178-1183 5 p.Research output: Contribution to journal › Article › peer-review
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The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
Herrero-Mendez, A., Almeida, A., Fernández, E., Maestre, C., Moncada, S. & Bolaños, J. P., 2009, In: Nature Cell Biology. 11, 6, p. 747-752 5 p.Research output: Contribution to journal › Article › peer-review
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2008
The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning
Lafuente, N., Matesanz, N., Azcutia, V., Romacho, T., Nevado, J., Rodríguez-Mañas, L., Moncada, S., Peiró, C. & Sánchez-Ferrer, C. F., Mar 2008, In: Journal of hypertension. 26, 3, p. 478-485 7 p.Research output: Contribution to journal › Article › peer-review
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2007
Cytochrome c oxidase maintains mitochondrial respiration during partial inhibition by nitric oxide
Palacios-Callender, M., Hollis, V., Frakich, N., Mateo, J. & Moncada, S., 1 Jan 2007, In: Journal of Cell Science. 120, 1, p. 160-165 5 p.Research output: Contribution to journal › Article › peer-review
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Cytochrome c oxidase regulates endogenous nitric oxide availability in respiring cells: A possible explanation for hypoxic vasodilation
Palacios-Callender, M., Hollis, V., Mitchison, M., Frakich, N., Unitt, D. & Moncada, S., 20 Nov 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 47, p. 18508-18513 5 p.Research output: Contribution to journal › Article › peer-review
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Defective mitochondrial biogenesis: A hallmark of the high cardiovascular risk in the metabolic syndrome?
Nisoli, E., Clementi, E., Carruba, M. O. & Moncada, S., Mar 2007, In: Circulation research. 100, 6, p. 795-806 11 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide and hypoxia
Galkin, A., Higgs, A. & Moncada, S., 2007, In: Essays in biochemistry. 43, p. 29-42 13 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide and mitochondrial signaling: From physiology to pathophysiology
Erusalimsky, J. D. & Moncada, S., Dec 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 12, p. 2524-2531 7 p.Research output: Contribution to journal › Article › peer-review
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Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress
Diaz-Hernandez, J. I., Moncada, S., Bolaños, J. P. & Almeida, A., Jun 2007, In: Cell Death and Differentiation. 14, 6, p. 1211-1221 10 p.Research output: Contribution to journal › Article › peer-review
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S-nitrosation of mitochondrial complex I depends on its structural conformation
Galkin, A. & Moncada, S., 28 Dec 2007, In: Journal of Biological Chemistry. 282, 52, p. 37448-37453 5 p.Research output: Contribution to journal › Article › peer-review
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Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
Funes, J. M., Quintero, M., Henderson, S., Martinez, D., Qureshi, U., Westwood, C., Clements, M. O., Bourboulia, D., Pedley, R. B., Moncada, S. & Boshoff, C., 10 Apr 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 15, p. 6223-6228 5 p.Research output: Contribution to journal › Article › peer-review
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2006
Adventures in vascular biology: A tale of two mediators
Moncada, S., 2006, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 361, 1469, p. 735-759 24 p.Research output: Contribution to journal › Article › peer-review
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Inhibition of cellular respiration by endogenously produced carbon monoxide
D'Amico, G., Lam, F., Hagen, T. & Moncada, S., 1 Jun 2006, In: Journal of Cell Science. 119, 11, p. 2291-2298 7 p.Research output: Contribution to journal › Article › peer-review
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Mitochondria as signaling organelles in the vascular endothelium
Quintero, M., Colombo, S. L., Godfrey, A. & Moncada, S., 4 Apr 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 14, p. 5379-5384 5 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide, cell bioenergetics and neurodegeneration
Moncada, S. & Bolaños, J. P., Jun 2006, In: Journal of neurochemistry. 97, 6, p. 1676-1689 13 p.Research output: Contribution to journal › Article › peer-review
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Nitric Oxide. In: Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery
Carre, J., Singer, M. & Moncada, S., 2006, Springer Nature.Research output: Book/Report › Book › peer-review
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Nitric oxide and the vascular endothelium
Moncada, S. & Higgs, E. A., 2006, In: Handbook of Experimental Pharmacology. 176, 1, p. 213-254 41 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1α in cancer: Role of free radical formation
Quintero, M., Brennan, P. A., Thomas, G. J. & Moncada, S., 15 Jan 2006, In: Cancer Research. 66, 2, p. 770-774 4 p.Research output: Contribution to journal › Article › peer-review
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Sir John Robert Vane: 29 March 1927 - 19 November 2004.
Moncada, S., 2006, In: Royal Society of London. Biographical Memoirs of Fellows of the Royal Society. 52, p. 401-411 10 p.Research output: Contribution to journal › Article › peer-review
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The discovery of nitric oxide and its role in vascular biology
Moncada, S. & Higgs, E. A., Jan 2006, In: British Journal of Pharmacology. 147, 1, p. S193-S201Research output: Contribution to journal › Article › peer-review
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TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
Valerio, A., Cardile, A., Cozzi, V., Bracale, R., Tedesco, L., Pisconti, A., Palomba, L., Cantoni, O., Clementi, E., Moncada, S., Carruba, M. O. & Nisoli, E., 2 Oct 2006, In: Journal of Clinical Investigation. 116, 10, p. 2791-2798 7 p.Research output: Contribution to journal › Article › peer-review
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2005
Cell biology: Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
Nisoli, E., Tonello, C., Cardile, A., Cozzi, V., Bracale, R., Tedesco, L., Falcone, S., Valerio, A., Cantoni, O., Clementi, E., Moncada, S. & Carruba, M. O., 14 Oct 2005, In: Science. 310, 5746, p. 314-317 3 p.Research output: Contribution to journal › Article › peer-review
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Discrepancies between nitroglycerin and NO-releasing drugs on mitochondrial oxygen consumption, vasoactivity, and the release of NO
Núñez, C., Víctor, V. M., Tur, R., Alvarez-Barrientos, A., Moncada, S., Esplugues, J. V. & D'Ocón, P., Nov 2005, In: Circulation research. 97, 10, p. 1063-1069 6 p.Research output: Contribution to journal › Article › peer-review
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GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo
Alderton, W. K., Angell, A. D. R., Craig, C., Dawson, J., Garvey, E., Moncada, S., Monkhouse, J., Rees, D., Russell, L. J., Russell, R. J., Schwartz, S., Waslidge, N. & Knowles, R. G., Jun 2005, In: British Journal of Pharmacology. 145, 3, p. 301-312 11 p.Research output: Contribution to journal › Article › peer-review
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Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages
Frost, M. T., Wang, Q., Moncada, S. & Singer, M., Feb 2005, In: AJP: Regulatory, Integrative and Comparative Physiology. 288, 2, p. R394-R400Research output: Contribution to journal › Article › peer-review
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Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo
Scotland, R. S., Madhani, M., Chauhan, S., Moncada, S., Andresen, J., Nilsson, H., Hobbs, A. J. & Ahluwalia, A., 15 Feb 2005, In: Circulation. 111, 6, p. 796-803 7 p.Research output: Contribution to journal › Article › peer-review
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Nitric oxide: Orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response
Xu, W., Charles, I. G. & Moncada, S., 2005, In: Cell Research. 15, 1, p. 63-65 2 p.Research output: Contribution to journal › Article › peer-review
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Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis
Herman, A. G. & Moncada, S., Oct 2005, In: European Heart Journal. 26, 19, p. 1945-1955 10 p.Research output: Contribution to journal › Article › peer-review
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2004
Adventures in pharmacology, aspirin, prostacyclin and nitric oxide
Moncada, S., 2004, In: Acta Cardiologica. 59, 1, p. 47-50 3 p.Research output: Contribution to journal › Article › peer-review
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Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
Ahluwalia, A., Foster, P., Scotland, R. S., McLean, P. G., Mathur, A., Perretti, M., Moncada, S. & Hobbs, A. J., 3 Feb 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 5, p. 1386-1391 5 p.Research output: Contribution to journal › Article › peer-review
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Can endogenous gaseous messengers control mitochondrial biogenesis in mammalian cells?
Nisoli, E., Clementi, E., Tonello, C., Moncada, S. & Carruba, M. O., Jan 2004, In: Prostaglandins and Other Lipid Mediators. 73, 1-2, p. 9-27 18 p.Research output: Contribution to journal › Article › peer-review
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Endogenous NO regulates superioxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase
Palacios-Callender, M., Quintero, M., Hollis, V. S., Springe, R. J. & Moncada, S., 18 May 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7630-7635 5 p.Research output: Contribution to journal › Article › peer-review
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Inhibition of mitochondrial respiration by the anticancer agent 2-methoxyestradiol
Hagen, T., D'Amico, G., Quintero, M., Palacios-Callender, M., Hollis, V., Lam, F. & Moncada, S., 24 Sept 2004, In: Biochemical and Biophysical Research Communications. 322, 3, p. 923-929 6 p.Research output: Contribution to journal › Article › peer-review