Samrina Rehman, PhD MRSC

Dr

Personal profile

Biography

Samrina graduated with an MChem with Honours in Chemistry with Medicinal Chemistry from The University of Manchester and an MSc in Cheminformatics from UMIST. She gained industrial experience as an electroplating chemist. Following her master's degree, she joined Inpharmatica, and contributed to the company’s pioneering proprietary chemogenomic drug-discovery databases now integrated into ChEMBL, a crucial resource today for drug discovery researchers. She earned a PhD in Systems Biology at the University of Manchester, where she pioneered the application of systems biology methods to investigate Dupuytren biology. Her postdoctoral research focused on stressed networks in liver disease and involved patient-derived iPSCs. In parallel, she developed mathematical models to understand chronic myeloid leukemia, and urothelial cancer. This work earned her a prestigious Unilever fellowship to study the metabolome of the human scalp. This work further expanded to the transcriptomes and lipidomes which were integrated with systems biology methods. Samrina has worked at Evotec SE, applying her expertise in systems biology and computational methods to enhance drug discovery services, including work on Facioscapulohumeral Muscular Dystrophy. In 2019, Samrina joined Medicines Discovery Catapult, where she provides bioinformatics support to the UK life sciences and drug discovery SME community. Her role involves supporting immuno-oncology projects and leading an informatics collaborations on motor neurone disease and multiple sclerosis. Additionally, she is engaged in projects on healthy ageing, neuropathic pain and mental health disorders. She is an honorary senior research fellow at FBMH, and serves on the American Dupuytren’s Foundation research committee.
 

Qualifications

  • PhD Systems Biology, University of Manchester, 2011
  • MSc Cheminformatics, UMIST/University of Manchester, 2005
  • MChem Hons. Chemistry, University of Manchester, 2004

Research interests

Application of informatics, modelling and systems biology tools and techniques to help unravel the complexity of human physiology and address challenges in a range of clinical conditions, disease and also gerontology. Projects span across several medical areas i.e. connective tissue disorders, plastic & reconstructive surgery research, hepatology, neurology (motor neurone disease and multiple sclerosis), neuropathic pain and also healthy ageing.

  • Medical systems biology
  • Biomarker and drug discovery
  • Clinical metabolomics
  • Cancer and stem cell research
  • Informatics, machine learning, multivariate data analysis, biostatistics.

Impact

Awards, Grants and Prizes

  • Strada Leadership Scholarship,  for pursuing EMBA. This award recognises exceptional academic merit and career achievement, Quantic School of Business & Technology, (USD 3,500), Aug 2023
  • Global Challenges Research Fund Institutional Sponsorship (£salary)(Prof. A Masters, (total value GBP 5,400)), Feb 2017 
  • Unilever Sponsorships awarded (£salary) - Multiple sponsorships in collaboration with Prof. HV Westerhoff, (totaling GBP 235,000), Nov 2013 and Dec 2014    
  • Best poster award sponsored by Biocrates Life Sciences at the 2nd Metabolomics & Systems Biology conference, Chicago, USA, Apr 2013
  • Scoping Project funds (with Prof. HV Westerhoff), Unilever UK & Ireland, (totaling GBP 20,472), Oct 2012  and Mar 2013           
  • Invitrogen award to present at University of California, Irvine, USA (USD 1000), May 2010

News

Memberships of committees and professional bodies

  • American Medical Informatics Association, 2024-
  • OBN (UK), 2024-
  • Applied Microbiology International, 2023-
  • British Society for Research on Ageing, 2022-
  • Data Science Foundation, 2020-
  • British Society for Antimicrobial Chemotherapy, 2019-
  • Duypuytren Research Committee, 2017-
  • Biochemical Society (a FEBS constituent society), 2007-
  • Royal Society of Chemistry, 2006-

My collaborations

Please see Samrina's publications for indications of her extensive international collaboration network.

Other

Not for profit Dupuytrens Research Foundation

Industry Unilever UK, Evotec UK

 

Opportunities

Contact:

For academic/research collaborations please contact: Samrina.Rehman@manchester.ac.uk

For industrial, commercial and translational research interest please contact: Samrina.Rehman@md.catapult.org.uk

 

 

 

 

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 17 - Partnerships for the Goals

Education/Academic qualification

Doctor of Philosophy, A Systems approach to understand Dupuytren's disease

1 Jan 200710 Jun 2011

Award Date: 13 Dec 2011

External positions

Scientist, Infrastructure for Systems Biology Europe

Bioinformatics Data Scientist, Medicines Discovery Catapult Ltd

Research Beacons, Institutes and Platforms

  • Digital Futures
  • Cancer
  • Institute for Data Science and AI

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