Samrina Rehman, MChem MSc PhD MRSC

Dr

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Personal profile

Biography

Samrina studied Chemistry followed by MSc Cheminformatics at the University of Manchester, and then joined Inpharmatica Ltd, a former informatics-driven drug discovery company. Some of her work was integrated into what is now known as ChEMBLdb. She then completed a Ph.D. pioneering the application of systems biology methods to analyse Dupuytren biology, followed by postdoctoral research applying these methods to investigate liver disease (functional genomic data from patient-derived iPSCs), chronic myeloid leukemia, and urothelial cancer and later secured a fellowship sponsored by Unilever to investigate the metabolome of the human scalp. Samrina then joined Evotec SE bringing her expertise in systems biology, functional genomics data integration, and computational methods to complement and enhance Evotec’s drug discovery services. In 2019, Samrina joined the Medicines Discovery Catapult where she provides bioinformatics support to the UK life science and drug discovery SME community and supports a portfolio of immuno-oncology projects with a leading medical research charity. She is also leading an informatics collaboration on motor neurone disease with the charitable trust and is engaged in projects on healthy ageing and neuropathic pain. Samrina is an honorary senior research fellow at the University of Manchester and a member of the American Dupuytren’s Foundation research committee.

Research interests

Application of informatics, modelling and systems biology tools and techniques to help unravel the complexity of human physiology and address challenges in a range of clinical conditions, disease and also gerontology. Projects span across several medical areas i.e. connective tissue disorders, plastic & reconstructive surgery research, hepatology, neurology (motor neurone disease and multiple sclerosis), neuropathic pain and also healthy ageing.

  • Medical systems biology
  • Biomarker and drug discovery
  • Clinical metabolomics
  • Cancer and stem cell research
  • Informatics, machine learning, multivariate data analysis, biostatistics.

Qualifications

  • PhD Systems Biology, University of Manchester, 2011
  • MSc Cheminformatics, UMIST/University of Manchester, 2005
  • MChem Hons. Chemistry, University of Manchester, 2004

Memberships of committees and professional bodies

  • Royal Society of Chemistry, 2006-
  • Biochemical Society (a FEBS constituent society), 2007-
  • Duypuytren Research Committee, 2017-
  • British Society for Antimicrobial Chemotherapy, 2019-
  • Data Science Foundation, 2020-
  • British Society for Research on Ageing, 2022-

Impact

Awards/Grants/Prizes/News

  • In the news: Dupuytrens' Disease Maps
  • Global Challenges Research Fund Institutional Sponsorship (£salary)(Prof. A Masters, total value £5,400), Feb 2017 
  • In the news: Statification of the severity of Non-Alcoholic Fatty Liver Disease
  • Unilever Sponsorship awarded (£salary) (with Prof. HV Westerhoff, total value £55,000), Dec 2014
  • Unilever Sponsorship awarded (£salary) (with Prof. HV Westerhoff, total value £180,000), Nov 2013     
  • Best poster award sponsored by Biocrates Life Sciences at the 2nd Metabolomics & Systems Biology conference, Chicago, USA, Apr 2013
  • Scoping Project funds extended (with Prof. HV Westerhoff), Unilever UK & Ireland, (£4,085), Mar 2013
  • Scoping Project funds (with Prof. HV Westerhoff), Unilever UK & Ireland, (£16,387), Oct 2012             
  • Invitrogen award to present at University of California, Irvine, USA ($1000), May 2010

My collaborations

Please see Samrina's publications for indications of her extensive international collaboration network.

Other

Not for profit Dupuytrens Research Foundation

Industry Unilever UK, Evotec UK

 

Opportunities

Contact:

For academic/research collaborations please contact: Samrina.Rehman@manchester.ac.uk

For industrial, commercial and translational research interest please contact: Samrina.Rehman@md.catapult.org.uk

 

 

 

 

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 17 - Partnerships for the Goals

Education/Academic qualification

Doctor of Philosophy, A Systems approach to understand Dupuytren's disease

1 Jan 200710 Jun 2011

Award Date: 13 Dec 2011

External positions

Scientist, Infrastructure for Systems Biology Europe

Bioinformatics Data Scientist, Medicines Discovery Catapult Ltd

Research Beacons, Institutes and Platforms

  • Digital Futures
  • Cancer
  • Institute for Data Science and AI

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