Research output per year
Research output per year
- 15 results
Search results
-
2024
An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies
Nagarajan, S. & et al., 1 Feb 2024, In: Gastroenterology. 166, 2, p. 298-312.e14Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
2020
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
Nagarajan, S., Rao, S. V., Sutton, J., Cheeseman, D., Dunn, S., Papachristou, E. K., Prada, J.-E. G., Couturier, D.-L., Kumar, S., Kishore, K., Chilamakuri, C. S. R., Glont, S.-E., Archer Goode, E., Brodie, C., Guppy, N., Natrajan, R., Bruna, A., Caldas, C., Russell, A. & Siersbæk, R. & 3 others, , 1 Feb 2020, In: Nature Genetics. 52, 2, p. 187-197Research output: Contribution to journal › Article › peer-review
Open AccessFile235 Downloads (Pure) -
Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Haider, M.-T., Saito, H., Zarrer, J., Uzhunnumpuram, K., Nagarajan, S., Kari, V., Horn-glander, M., Werner, S., Hesse, E. & Taipaleenmäki, H., 1 Dec 2020, In: Breast Cancer Research. 22, 1Research output: Contribution to journal › Article › peer-review
Open Access -
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
Nagarajan, S., 14 Sept 2020, In: Cancer Cell. 38, 3, p. 412-423.e9Research output: Contribution to journal › Article › peer-review
Open Access -
2019
VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer
Holding, A. N., Giorgi, F. M., Donnelly, A., Cullen, A. E., Nagarajan, S., Selth, L. A. & Markowetz, F., 1 Dec 2019, In: Genome biology. 20, 1Research output: Contribution to journal › Article › peer-review
Open Access -
2018
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart
Iyer, L. M., Nagarajan, S., Woelfer, M., Schoger, E., Khadjeh, S., Zafiriou, M. P., Kari, V., Herting, J., Pang, S. T., Weber, T., Rathjens, F. S., Fischer, T. H., Toischer, K., Hasenfuss, G., Noack, C., Johnsen, S. A. & Zelarayán, L. C., 6 Apr 2018, In: Nucleic acids research. 46, 6, p. 2850-2867Research output: Contribution to journal › Article › peer-review
Open Access -
2017
BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire
Najafova, Z., Tirado-magallanes, R., Subramaniam, M., Hossan, T., Schmidt, G., Nagarajan, S., Baumgart, S. J., Mishra, V., Bedi, U., Hesse, E., Knapp, S., Hawse, J. R. & Johnsen, S. A., 9 Jan 2017, In: Nucleic acids research. 45, 1, p. 127-141Research output: Contribution to journal › Article › peer-review
Open Access -
CHD1 regulates cell fate determination by activation of differentiation-induced genes
Baumgart, S. J., Najafova, Z., Hossan, T., Xie, W., Nagarajan, S., Kari, V., Ditzel, N., Kassem, M. & Johnsen, S. A., 27 Jul 2017, In: Nucleic acids research. 45, 13, p. 7722-7735Research output: Contribution to journal › Article › peer-review
Open Access -
Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism
Mishra, V. K., Subramaniam, M., Kari, V., Pitel, K. S., Baumgart, S. J., Naylor, R. M., Nagarajan, S., Wegwitz, F., Ellenrieder, V., Hawse, J. R. & Johnsen, S. A., 1 May 2017, In: Cancer Research. 77, 9, p. 2387-2400Research output: Contribution to journal › Article › peer-review
-
RNF40 regulates gene expression in an epigenetic context-dependent manner
Xie, W., Nagarajan, S., Baumgart, S. J., Kosinsky, R. L., Najafova, Z., Kari, V., Hennion, M., Indenbirken, D., Bonn, S., Grundhoff, A., Wegwitz, F., Mansouri, A. & Johnsen, S. A., 1 Dec 2017, In: Genome biology. 18, 1, 32.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3
Jozwik, K. M., Chernukhin, I., Serandour, A. A., Nagarajan, S. & Carroll, J. S., 1 Dec 2016, In: Cell Reports. 17, 10, p. 2715-2723Research output: Contribution to journal › Article › peer-review
Open Access -
Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation: SSSRP1 regulates osteoblast differentiation through Wnt-signaling pathway
Hossan, T., Nagarajan, S., Baumgart, S. J., Xie, W., Magallanes, R. T., Hernandez, C., Chiaroni, P.-M., Indenbirken, D., Spitzner, M., Thomas-chollier, M., Grade, M., Thieffry, D., Grundhoff, A., Wegwitz, F. & Johnsen, S. A., 1 May 2016, In: Stem Cells. 34, 5, p. 1369-1376Research output: Contribution to journal › Article › peer-review
Open Access -
2015
H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription
Nagarajan, S., Benito, E., Fischer, A. & Johnsen, S. A., 30 Mar 2015, In: Oncotarget. 6, 9, p. 7305-7317Research output: Contribution to journal › Article › peer-review
Open Access -
NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas
Chen, N.-M., Singh, G., Koenig, A., Liou, G.-Y., Storz, P., Zhang, J.-S., Regul, L., Nagarajan, S., Kühnemuth, B., Johnsen, S. A., Hebrok, M., Siveke, J., Billadeau, D. D., Ellenrieder, V. & Hessmann, E., 1 May 2015, In: Gastroenterology. 148, 5, p. 1024-1034.e9Research output: Contribution to journal › Article › peer-review
-
2014
Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription
Nagarajan, S., Hossan, T., Alawi, M., Najafova, Z., Indenbirken, D., Bedi, U., Taipaleenmäki, H., Ben-batalla, I., Scheller, M., Loges, S., Knapp, S., Hesse, E., Chiang, C.-M., Grundhoff, A. & Johnsen, S., 1 Jul 2014, In: Cell Reports. 8, 2, p. 460-469Research output: Contribution to journal › Article › peer-review
Open Access