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Personal profile

Overview

I have been interested in the fundamental questions behind clinical conditions from the beginning of my medical training. I completed a PhD in gene therapy in 2011 whilst at medical school through the MB PhD program at UCL. In my postgraduate training I became fascinated with disorders of the respiratory system and how the immune system can influence pathogenesis and clinical course. I have used NIHR funded posts to develop a core theme of respiratory immunology that I have applied to a broad range of respiratory conditions, most notably lung cancer and the recent COVID-19 pandemic.

Biography

Following an intercalated BSc in Immunology, I joined the MB PhD program at UCL in 2008. This led to a PhD in gene therapy, where I worked on how retroviral vectors dysregulate neighbouring gene expression. I also developed a new production system for lentiviral vectors that is scalable, enabling sufficient quantities of vector for widespread application. I graduated from UCL medical school in 2013 and joined the academic foundation program in Cambridge. I started a Respiratory Academic Clinical Fellowship in London in 2015 and relocated to the North West in 2017. I am now an Academic Clinical Lecturer and specialist registrar in Respiratory Medicine

Further information

sean.knight@manchester.ac.uk

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Bachelor of Medicine and Bachelor of Surgery, University College London (UCL)

Award Date: 15 Jul 2013

Doctor of Philosophy, Lentiviral Vectors for Gene Therapy, University College London (UCL)

Award Date: 28 Mar 2012

Bachelor of Science, Immunology and Cell Pathology, University College London (UCL)

Award Date: 1 Aug 2007

External positions

Honorary Respiratory Registrar, Salford Royal NHS Foundation Trust

8 Aug 20197 Aug 2020

Areas of expertise

  • R Medicine (General)
  • Respiratory Medicine

Research Beacons, Institutes and Platforms

  • Cancer
  • Lydia Becker Institute

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Collaborations and top research areas from the last five years

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