Research output per year
Research output per year
Search results
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2024
211 Systemic inflammation leads to neuronal loss and exacerbates behavioural deficits in a mouse model of MPS IIIA
Mandolfo, O., Parker, H., Aguado, È., Learmonth, Y. I., Liao, A., O'Leary, C., Ellison, S. M., Taylor, J., Wood, S. R., Holley, R., Boutin, H. & Bigger, B., Feb 2024, In: Molecular genetics and metabolism. 141, 2, 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Systemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease
Mandolfo, O., Parker, H., Aguado, È., Ishikawa Learmonth, Y., Liao, A. Y., O'Leary, C., Ellison, S., Forte, G., Taylor, J., Wood, S., Searle, R., Holley, R. J., Boutin, H. & Bigger, B. W., 15 Jul 2024, In: EMBO Molecular Medicine. 16, 7, p. 1579-1602 24 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Fusion of Rabies Virus Glycoprotein or gh625 to Iduronate-2-Sulfatase for the Treatment of Mucopolysaccharidosis Type II
Wood, S., Chaudrhy, A., Ellison, S., Searle, R., Burgod, C., Tehseen, G., Forte, G., O'Leary, C., Gleitz, H., Liao, A., Cook, J., Holley, R. & Bigger, B., 7 Jul 2023, In: Human Gene Therapy.Research output: Contribution to journal › Article › peer-review
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Sustained long-term disease correction in a murine model of MPSII following stem cell gene therapy
Ellison, S., Liao, A., Gleitz, H. F. E., Parker, H., Booth, L., Robinson, J., Wood, S., Taylor, J., Holley, R. & Bigger, B. W., 14 Dec 2023, In: Molecular Therapy - Methods & Clinical Development. 31, 101127.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Delivering gene therapy for mucopolysaccharide diseases
Wood, S. & Bigger, B., 12 Sept 2022, In: Frontiers in Molecular Biosciences.Research output: Contribution to journal › Review article › peer-review
Open AccessFile292 Downloads (Pure) -
2020
Actinomycin D Downregulates Sox2 and Improves Survival in Preclinical Models of Recurrent Glioblastoma
Taylor, J. T., Ellison, S., Pandele, A., Wood, S., Nathan, E., Forte, G., Parker, H., Zindy, E., Elvin, M., Dickson, A., Williams, K. J., Karabatsou, K., McCabe, M., McBain, C. & Bigger, B. W., 30 Mar 2020, In: Neuro-Oncology. 22, 9, p. 1289-1301 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
A quantitative chloride channel conductance assay for efficacy testing of AAV.BEST1
Wood, S., McClements, M. E., Martinez-Fernandez de la Camara, C., Patricio, M. M., Uggenti, C., Sekaran, S., Barnard, A. R., Manson, F. & MacLaren, R. E., 2019, In: Human Gene Therapy Methods.Research output: Contribution to journal › Article › peer-review
Open AccessFile215 Downloads (Pure) -
Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA
Ellison, S. M., Liao, A., Wood, S., Taylor, J., Youshani, A. S., Rowlston, S., Parker, H., Armant, M., Biffi, A., Chan, L., Farzaneh, F., Wynn, R., Jones, S. A., Heal, P., Gaspar, H. B. & Bigger, B. W., 14 Jun 2019, In: Molecular Therapy - Methods and Clinical Development. 13, p. 399-413 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Delivering Hematopoietic Stem Cell Gene Therapy Treatments for Neurological Lysosomal Diseases.
Holley, R., Wood, S. & Bigger, B., 2018, In: ACS Chemical Neuroscience.Research output: Contribution to journal › Review article › peer-review
Open AccessFile40 Downloads (Pure)