Personal profile
Overview
I am an Academic Clinical Lecturer in Obstetrics in the Maternal and Fetal Health Research Centre. I completed my undergraduate medical degree and MRes in Medical Sciences at the University of Manchester, graduating in 2009. I have undertaken Integrated Clinical Academic Training and completed my PhD in 2019, funded by a MRC / RCOG Clinical Research Training Fellowship.
My research interest lies in understanding maternal vascular physiology and identifying new treatments for maternal vascular dysfunction in hypertensive disorders of pregnancy.
I am passionate about small artery function and enjoy balancing long experimental days in the lab with the adrenaline of working on a busy delivery unit. I am enthusiastic about encouraging young clinicians to try laboratory science.
Education/Academic qualification
Doctor of Philosophy, The University of Manchester
Award Date: 20 Dec 2019
Master of Research, The University of Manchester
Award Date: 1 Jul 2009
Bachelor of Medicine and Bachelor of Surgery, The University of Manchester
Award Date: 1 Jul 2009
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy
Ormesher, L., Worton, S. A., Best, A., Dodd, S. R., Dempsey, A., Cottrell, E. C., Glossop, H., Chmiel, C., Wu, H. Y., Hardwick, B., Hennessy, S., Johnstone, E. D. & Myers, J. E., 1 Feb 2024, In: REPRODUCTIVE SCIENCES. 31, 2, p. 560-568 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Kynurenine Relaxes Arteries of Normotensive Women and Those with Preeclampsia
Worton, S. A., Pritchard, H. A., Greenwood, S. L., Alakrawi, M., Heazell, A. E., Wareing, M., Greenstein, A. S. & Myers, J. E., 3 Mar 2021, In: Circulation research.Research output: Contribution to journal › Article › peer-review
Open Access -
The kynurenine pathway; A new target for treating maternal features of preeclampsia?
Worton, S. A., Greenwood, S. L., Wareing, M., Heazell, A. E. & Myers, J., 1 May 2019, In: Placenta. 84, p. 44-49Research output: Contribution to journal › Review article › peer-review
Open Access -
IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics; biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth and fetal growth restriction.
Barbaux, S., Erwich, J. J. H. M., Favaron, P. O., Gil, S., Gallot, D., Golos, T. G., Gonzalez-Bulnes, A., Guibourdenche, J., Heazell, A. E. P., Jansson, T., Laprévote, O., Lewis, R. M., Miller, R. K., Monk, D., Novakovic, B., Oudejans, C., Parast, M., Peugnet, P., Pfarrer, C. & Pinar, H. & 13 others, , Apr 2015, In: Placenta. 36 Suppl 1Research output: Contribution to journal › Article › peer-review
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Antenatal glucocorticoid exposure and long-term alterations in aortic function and glucose metabolism
Kelly, B. A., Lewandowski, A. J., Worton, S. A., Davis, E. F., Lazdam, M., Francis, J., Neubauer, S., Lucas, A., Singhal, A. & Leeson, P., May 2012, In: Pediatrics. 129, 5, p. e1282-90Research output: Contribution to journal › Article › peer-review
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Maternal & Fetal Health Research Centre
Stevens, A. (PI), Heazell, A. (PI), Tower, C. (PI), Brison, D. (PI), Johnstone, E. (PI), Cottrell, E. (PI), Mann, E. (PI), Ingram, E. (PI), Crocker, I. (PI), Chernyavsky, I. (PI), Myers, J. (PI), Aplin, J. (PI), Higgins, L. (PI), Harris, L. (PI), Dilworth, M. (PI), Westwood, M. (PI), Whitworth, M. (PI), Desforges, M. (PI), Brownbill, P. (PI), Ruane, P. (PI), Sturmey, R. (PI), Worton, S. (PI), Greenwood, S. (PI), Sibley, C. (PI), Belchamber, K. (PI), Palin, V. (PI), Povey, A. (PI), Ormesher, L. (PI) & Perchard, R. (PI)
1/09/18 → 31/12/35
Project: Research
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Tommy's 2024-2025 Annual Budget
Heazell, A. (PI), Aplin, J. (CoI), Brownbill, P. (CoI), Cottrell, E. (CoI), Desforges, M. (CoI), Dilworth, M. (CoI), Higgins, L. (CoI), Johnstone, E. (CoI), Myers, J. (CoI), Palin, V. (CoI), Ruane, P. (CoI), Stevens, A. (CoI), Tropea, T. (CoI), Westwood, M. (CoI) & Worton, S. (CoI)
1/04/24 → 31/03/25
Project: Research
Thesis
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Can Kynurenine Pathway Manipulation Ameliorate Maternal Vascular Features of Preeclampsia?
Bosworth-Worton, S. (Author), Greenwood, S. (Co Supervisor), Myers, J. (Main Supervisor), Heazell, A. (Co Supervisor) & Wareing, M. (Co Supervisor), 12 Nov 2019Student thesis: Phd
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