Research output per year
Research output per year
Prof
I was appointed to the Chair of Imaging Science at Manchester University in 1999 to bring expertise in MR imaging techniques and their application in biology and medicine.
My research is based on the use of magnetic resonance techniques (imaging - MRI; spectroscopy - MRS) to understand normal physiology/biochemistry and how these become deranged in disease. I research into the development of new techniques but also the application of existing techniques in human disease and animal models. I have established valuable collaborations with a number of research groups in Manchester (see below) which have led to PhD studentships, programme grants, project grants and joint academic appointments as well as publications and abstracts. My main areas of interest are: (i) functional MRI of the brain, in the use of pharmacological challenge to probe the brain areas which respond to drugs, in gut-brain interactions and in appetite regulation. This work is carried out in human volunteers, psychiatric patients and animals; (ii) MRS of the brain, particularly the measurement of glutamate and GABA in psychiatric disease and in cortical plasticity; (iii) studies of anti-vascular agents in rodent models using contrast-enhanced MRI.
I am a member of the Diabetes and Obesity Research Network. My research interests in this area include:
I am the local PI for the UoM arm of the UK Regenerative Medicine Platform Safety Hub (led by Liverpool, with Manchester, Edinburgh Universities and UCL) bringing imaging techniques to bear on establishing safety and efficacy of stem cell therapies. This has involved extensive collaboration within Manchester (Susan Kimber, Adrian Woolfe, Marie-Claude Asselin) and outside:
I have previously been Postgraduate Tutor and MSc Programme Lead in the Centre. Now my main contribution to students (both undergraduate and post graduate) is through research supervision of projects (Medical School u/g, MSc and Ph.D.), module leader on the MSc in 'Medical Imaging', contributor of lectures on other modules and courses and as a Tutor for Personal and Professional Development for 1st and 2nd Year Medical students.
Geoff Parker, Marie-Claude Asselin, Rainer Hinz: Imaging Science
Shaheen Hamdy: GI Sciences
Bill Deakin, Ian Anderson, Rebecca Elliott, Shane McKie, Laura Parkes, Matt Lambon-Ralph: Experimental Neuroscience
Andrew Renehan: Cancer Science
Adrian Woolfe: Human Development
Susan Kimber: Cell Matrix Biology
Patricia Murray and Matt Rosseinsky: Liverpool University
Caroline Rae: University of New South Wales
Cristina Cudalbu: EPF Lausanne
1977 BA (Hons) Chemistry, Merton College Oxford
1980 D.Phil Biochemistry, Merton and Linacre Colleges Oxford
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to conference › Poster › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Parker, G. (PI), Asselin, M.-C. (CoI), Boutin, H. (CoI), Burns, A. (CoI), Herholz, K. (CoI), Matthews, J. (CoI), Parkes, L. (CoI) & Williams, S. (CoI)
1/01/15 → 28/02/19
Project: Research
Williams, S. (PI), Asselin, M.-C. (CoI), Kimber, S. (CoI), Lennon, R. (CoI) & Woolf, A. (CoI)
16/09/13 → 31/03/18
Project: Research
Hamdy, S. (PI) & Williams, S. (CoI)
5/01/12 → 30/06/18
Project: Research