Personal profile


Chondrocytes are cells that produce the specialised extracellular matrix that makes up cartilage. During development chondrocytes are responsible for forming the skeleton and in adulthood they maintain the articular cartilage of joints. I am interested in the molecular mechanisms that control chondrocyte phenotype during development and in diseases such as skeletal dysplasia and osteoarthritis. I am particularly interested in the function of microRNAs, the ion channel TRPV4 and the extracellular matrix proteins Matrilin-3 and COMP.

I completed my PhD project on ‘The role of osteoarthritis regulated microRNAs in skeletal development pathways’ under the supervision of Professor David Young at Newcastle University. I am currently a postdoctoral research associate in Professor Susan Kimber’s group at the University of Manchester, where I am using patient derived induced pluripotent stem cells (iPSCs) to model rare diseases of cartilage in vitro. I use a range of techniques including microarray, RNA-seq, stem cell culture/differentiation, CRISPR-Cas9, siRNA knockdown and luciferase reporter assays.    

Prizes and awards

  • Cartilage Gordon, Italy, Oral presentation prize, April 2017
  • 10th UK MSC meeting, York, Best oral presentation, December 2016
  • British Society of Matrix Biology (BSMB), Bristol, Poster prize, April 2011
  • Newcastle University research day, Newcastle, Poster prize, June 2010

Memberships of committees and professional bodies

British Society of Matrix Biology (BSMB)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


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Collaborations and top research areas from the last five years

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