Research output per year
Research output per year
Personal profile
Biography
B.Sc. (1971), Ph.D. (1974), Imperial College, London; Postdoctoral work, Geneva (1974-1976); Sussex(1976-1980); Lecturer/Senior Lecturer, Salford (1980-2001), UMIST (2001-2004).
Research interests
My research focus is the development and application of organic synthetic reactions. Particular interests include the metal-free radical cyclisation of unsaturated ketoesters, stereoselective electrocyclic and cycloaddition reactions, asymmetric induction using chiral auxiliaries, and axis-controlled biaryl synthesis. Targeted materials have included anticancer and antifungal agents, antimalarials, naturally occurring polyenes, terpenoids and axially-chiral amines.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
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Axial stereocontrol in: Tropos dibenz [c, e] azepines: The individual and cooperative effects of alkyl substituents
Balgobin, S. M. C., Brookes, D. J., Jiang, J., Pritchard, R. G. & Wallace, T. W., 2017, In: Organic and Biomolecular Chemistry. 15, 48, p. 10184-10199 16 p.Research output: Contribution to journal › Article › peer-review
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Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
France, S. P., Aleku, G. A., Sharma, M., Mangas-Sanchez, J., Howard, R. M., Steflik, J., Kumar, R., Adams, R. W., Slabu, I., Crook, R., Grogan, G., Wallace, T. W. & Turner, N. J., 2017, In: Angewandte Chemie - International Edition. 56, 49, p. 15589-15593 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
Tubulin-binding dibenz[c,e]oxepines: Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents
Rossington, S., Hadfield, J., Shnyder, S. D., Wallace, T. & Williams, K., 1 Mar 2017, In: Bioorganic and Medicinal Chemistry. 25, 5, p. 1630-1642 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile177 Downloads (Pure) -
Atroposelective formation of dibenz[c,e]azepines via intramolecular direct arylation with centre-axis chirality transfer
Cheetham, C. A., Massey, R. S., Pira, S. L., Pritchard, R. G. & Wallace, T. W., 21 Mar 2011, In: Organic and Biomolecular Chemistry. 9, 6, p. 1831-1838 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile188 Downloads (Pure) -
Tubulin-binding dibenz[c,e]oxepines as colchinol analogues for targeting tumour vasculature
Edwards, D. J., Hadfield, J. A., Wallace, T. W. & Ducki, S., 1 Jan 2011, In: Organic and Biomolecular Chemistry. 9, 1, p. 219-231 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile161 Downloads (Pure)
Datasets
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CCDC 276887: Experimental Crystal Structure Determination
Sheldrake, H. M. (Contributor), Wallace, T. (Contributor) & Wilson, C. P. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2006
DOI: 10.5517/cc993vj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc993vj&sid=DataCite
Dataset
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CCDC 1008372: Experimental Crystal Structure Determination
Balgobin, S. M. C. (Contributor), Brookes, D. J. (Contributor), Jiang, J. (Contributor), Pritchard, R. (Contributor) & Wallace, T. (Contributor), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/ccdc.csd.cc12v94c, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc12v94c&sid=DataCite
Dataset
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CCDC 679032: Experimental Crystal Structure Determination
Pritchard, R. (Contributor), Sheldrake, H. M. (Contributor), Taylor, I. Z. (Contributor) & Wallace, T. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2008
DOI: 10.5517/ccqsl8b, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccqsl8b&sid=DataCite
Dataset
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CCDC 1008371: Experimental Crystal Structure Determination
Balgobin, S. M. C. (Contributor), Brookes, D. J. (Contributor), Jiang, J. (Contributor), Pritchard, R. (Contributor) & Wallace, T. (Contributor), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/ccdc.csd.cc12v93b, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc12v93b&sid=DataCite
Dataset
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CCDC 793197: Experimental Crystal Structure Determination
Cheetham, C. A. (Contributor), Massey, R. S. (Contributor), Pira, S. L. (Contributor), Pritchard, R. (Contributor) & Wallace, T. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2011
DOI: 10.5517/ccvmd0v, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccvmd0v&sid=DataCite
Dataset