Research output per year
Research output per year
Personal profile
Biography
My key area of interest is the development and engineering of therapeutic proteins. I possess valuable experience from the biopharmaceutical industry, which I am bringing into my current research post at the University of Manchester. I understand the critical role biotechnology plays in the future of healthcare and I wish to continue to develop my career in this cutting edge and exciting field.
Research interests
The Interplay Between Aggregation and Immunogenicity in Biopharmaceuticals.
Two key concerns over product quality within the biopharmaceutical industry are immunogenicity and aggregation of therapeutic proteins. We are developing a model system to understand the interplay of aggregation and immunogenicity to aid development of improved quality, safer and more effective therapies.
This is a BBSRC LINK project in collaboration with Lonza - Applied Protein Services (Cambridge, UK).
Research Beacons, Institutes and Platforms
- Christabel Pankhurst Institute
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Research output
- 2 Article
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Use of peptide microarrays for fast and informative profiling of therapeutic antibody formulation conditions
Austerberry, J., Edwards, J., Eyes, T. & Derrick, J., 18 Oct 2021, In: Molecular Pharmaceutics.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Downloads (Pure) -
Identification of B cell epitopes enhanced by protein unfolding and aggregation
Eyes, T., Austerberry, J., Dearman, R., Johannissen, L., Kimber, I., Smith, N., Thistlethwaite, A. & Derrick, J., Jan 2019, In: Molecular immunology. 105, p. 181-189 8 p.Research output: Contribution to journal › Article › peer-review
Open Access
Thesis
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Deimmunisation oF Enhanced Green Fluorescent Protein
Author: Eyes, T., 1 Aug 2014Student thesis: Phd
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