Research output per year
Research output per year
Search results
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2024
25-hydroxycholesterol dysregulates brain endothelial cell function and exacerbates cerebral haemorrhage
Tapia, V. S., Withers, S., Zhou, R., Bennington, A., Hedley, F., El Khouja, A., Luka, N., Massimo, M., Crilly, S., Long, K., Lawrence, C. B. & Kasher, P., 10 May 2024, Cold Spring Harbor Laboratory Press, (bioRxiv).Research output: Preprint/Working paper › Preprint
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Developing an in vitro model of haematoma for study of intracerebral haemorrhage
Crilly, S., Tapia, V. S., Bawn, C. & Tirella, A., 17 Apr 2024, (Accepted/In press) In: Biomaterials Science.Research output: Contribution to journal › Article › peer-review
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Investigating recovery after a spontaneous intracerebral haemorrhage in zebrafish larvae
Crilly, S., Shand, I., Bennington, A., McMahon, E., Flatman, D., Tapia, V. S. & Kasher, P., 12 Sept 2024, In: Brain Communications. fcae310.Research output: Contribution to journal › Article › peer-review
Open Access -
Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions
Wellens, R., Tapia , V., Seoane Denicola, P., Bennett, H., Adamson, A., Coutts, G., Rivers-Auty, J., Lowe, M., Green, J., Lopez-Castejon, G., Brough, D. & Hoyle, C., 8 Aug 2024, In: Nature Communications. 15, 6750.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Characterization of a mutant samhd1 zebrafish model implicates dysregulation of cholesterol biosynthesis in Aicardi-Goutières syndrome
Withers, S., Rowlands, C., Tapia, V., Hedley, F., Mosneag, I., Crilly, S., Rice, G., Badrock, A., Hayes, A., Allan, S., Briggs, T. & Kasher, P., 6 Mar 2023, In: Frontiers in Immunology. 14, 11 p., 1100967.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Zebrafish drug screening identifies candidate therapies for neuroprotection after spontaneous intracerebral haemorrhage
Crilly, S., Parry-Jones, A., Wang, X., Selley, J., Cook, J., Tapia Olivares, V., Anderson, C. S., Allan, S. & Kasher, P., 29 Mar 2022, In: Disease Models & Mechanisms. 15, 3, dmm049227.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation
Lawrence, C. B., Rivers-Auty, J., Tapia Olivares, V., White, C., Daniels, M., Drinkall, S., Kennedy, P., Spence, H., Yu Shi, A., Green, J., Hoyle, C., Cook, J., Bradley, A., Mather, A., Peters, R., Tzeng, T.-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 31 Mar 2021, In: Journal of Neuroscience. 41 , 13, p. 3025–3038Research output: Contribution to journal › Article › peer-review
Open Access -
2019
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
Tapia, V. S., Daniels, M. J. D., Palazón-riquelme, P., Dewhurst, M., Luheshi, N. M., Rivers-auty, J., Green, J., Redondo-castro, E., Kaldis, P., Lopez-castejon, G. & Brough, D., 2019, In: Journal of Biological Chemistry. 294, 21, p. 8325-8335 11 p.Research output: Contribution to journal › Article › peer-review
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2018
Design, Synthesis and Evaluation of Novel Oxazaborine Inhibitors of the NLRP3 Inflammasome
Baldwin, A., Tapia Olivares, V., Swanton, T., White, C., Beswick, J., Brough, D. & Freeman, S., 2018, In: ChemMedChem.Research output: Contribution to journal › Article › peer-review
Open Access