Personal profile
Biography
I'm a First Year PhD Student under Professor David Wedge in the Manchester Cancer Research Centre. I'm a mathematician by trade but have extensively retrained in medicine and bioinformatics after a period working as a software engineer at NHS Digital.
My project is on developing new ML methods to analyse spatial transcriptomic data, and applying that to samples from Kenya, with the aim of understanding the specific aetiology of Prostate Cancer in African populations, which is systemically understudied.
I'm very interested in connecting with other people applying mathematics to genetic data, particularly in applications of topology and category theory.
Education/Academic qualification
Master in Science, MSc Health Data Science, The University of Manchester
2021 → 2022
Award Date: 13 Sept 2022
Master of Mathematics, MMathPhil Mathematics and Philosophy, Oxford University
2013 → 2017
Award Date: 30 Jun 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 10 Reduced Inequalities
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Research output
- 1 Article
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Investigating causal networks of dementia using causal discovery and natural language processing models
Yu, X. (Corresponding), Lophatananon, A., Holmes, V., Muir, K. & Guo, H. (Corresponding), 9 May 2025, In: npj Dementia. 1, 4.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Health Data Research UK Better Care North Partnership MSc Dissertation Placement
Holmes, V. (Recipient), 2022
Prize: Prize (including medals and awards)