Personal profile
Education/Academic qualification
Doctor of Philosophy, Statistics, University of Nottingham
Award Date: 15 Jul 2015
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Multiple origins and phenotypic implications of an extended human pseudoautosomal region shown by analysis of the UK Biobank
Poriswanish, N., Eales, J., Xu, X., Scannali, D., Neumann, R., Wetton, J. H., Tomaszewski, M., Jobling, M. A. & May, C. A., 3 Apr 2025, In: American Journal of Human Genetics. 112, 4, p. 927-939 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets
Human Kidney Tissue Resource Study Group, Xu, X., Khunsriraksakul, C., Eales, J. M., Rubin, S., Scannali, D., Saluja, S., Talavera, D., Markus, H., Wang, L., Drzal, M., Maan, A., Lay, A. C., Prestes, P. R., Regan, J., Diwadkar, A. R., Denniff, M., Rempega, G., Ryszawy, J. & Król, R. & 19 others, , 19 Mar 2024, In: Nature Communications. 15, 1, 2359.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.
Hughes, O., Bentley, A., Breeze, C., Aguet, F., Xu, X., Nadkarni, G., Sun, Q., Lin, B., Gilliland, T., Meyer, M., Du, J., Raffield, L., Kramer, H., Morton, R., Gouveia, M., Atkinson, E., Valladares-Salgado, A., Wacher-Rodarte, N., Dueker, N. & Guo, X. & 31 others, , 10 Jan 2024, In: Cell genomics. 4, 1, 100468.Research output: Contribution to journal › Article › peer-review
Open Access -
Interactive molecular causal networks of hypertension using a fast machine learning algorithm MRdualPC
Kelly, J., Xu, X., Eales, J. M., Keavney, B., Berzuini, C., Tomaszewski, M. & Guo, H., 2 Aug 2024, In: BMC Medical Research Methodology . 24, 1, 168.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure
Siedlinski, M., Carnevale, L., Xu, X., Carnevale, D., Evangelou, E., Caulfield, M. J., Maffia, P., Wardlaw, J., Samani, N. J., Tomaszewski, M., Lembo, G., Holmes, M. V. & Guzik, T. J., 14 Jun 2023, In: European Heart Journal . 44, 23, p. 2114-2125 12 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Normalised gene expression, miRNA expression and urinary transcriptomic data from Human Kidney Tissue Resource (HKTR)
Xu, X. (Creator), University of Manchester Figshare, 22 Mar 2024
DOI: 10.48420/24871785, https://figshare.manchester.ac.uk/articles/dataset/Normalised_gene_expression_miRNA_expression_and_urinary_transcriptomic_data_from_HKTR/24871785
Dataset
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Sample-size-balanced Genotype-Tissue Expression (GTEx) v8 prediction models for transcriptome-wide association studies (TWAS)
Xu, X. (Creator), University of Manchester Figshare, 22 Mar 2024
DOI: 10.48420/24871794, https://figshare.manchester.ac.uk/articles/dataset/Sample-size-balanced_GTEx_v8_TWAS_models/24871794
Dataset
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Summary statistics of UK Biobank blood pressure genome-wide association studies (GWAS) using 337,422 unrelated white European individuals
Xu, X. (Creator), Khunsriraksakul, C. (Contributor), Eales, J. M. (Contributor), Rubin, S. (Contributor), Scannali, D. (Contributor), Saluja, S. (Contributor), Talavera, D. (Contributor), Markus, H. (Contributor), Wang, L. (Contributor), Drzal, M. (Contributor), Maan, A. (Contributor), Lay, A. C. (Contributor), Prestes, P. R. (Contributor), Regan, J. (Contributor), Diwadkar, A. R. (Contributor), Denniff, M. (Contributor), Rempega, G. (Contributor), Ryszawy, J. (Contributor), Król, R. (Contributor), Dormer, J. P. (Contributor), Szulinska, M. (Contributor), Walczak, M. (Contributor), Antczak, A. (Contributor), Matías-García, P. R. (Contributor), Waldenberger, M. (Contributor), Woolf, A. S. (Contributor), Keavney, B. (Contributor), Zukowska-Szczechowska, E. (Contributor), Wystrychowski, W. (Contributor), Zywiec, J. (Contributor), Bogdanski, P. (Contributor), Danser, A. H. J. (Contributor), Samani, N. J. (Contributor), Guzik, T. J. (Contributor), Morris, A. (Contributor), Liu, D. J. (Contributor), Charchar, F. J. (Contributor) & Tomaszewski, M. (Contributor), University of Manchester Figshare, 22 Mar 2024
DOI: 10.48420/24851436, https://figshare.manchester.ac.uk/articles/dataset/UK_Biobank_blood_pressure_GWAS_summary_statistics_using_337_422_unrelated_white_European_individuals/24851436/2
Dataset
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Summary statistics of UK Biobank blood pressure genome-wide association studies (GWAS) using 337,422 unrelated white European individuals
Xu, X. (Creator), University of Manchester Figshare, 22 Mar 2024
DOI: 10.48420/24851436, https://figshare.manchester.ac.uk/articles/dataset/UK_Biobank_blood_pressure_GWAS_summary_statistics_using_337_422_unrelated_white_European_individuals/24851436/2
Dataset
Press/Media
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THE MIRROR: 'Piling on the pounds is crippling your kidneys but weight loss could reverse issues'
24/03/22
1 item of Media coverage
Press/Media: Research