Xiaoping Zhu

2024

Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study.

Lewis, D., Li, K.-L., Waqar, M., Coope, D., Pathmanaban, O., King, A., Djoukhadar, I., Zhao, S., Cootes, T., Jackson, A. & Zhu, X., 28 Feb 2024, In: Scientific Reports. 14, 4905 .

Research output: Contribution to journal › Article › peer-review

Open Access

2023

A Novel Multi-Model High Spatial Resolution Method for Analysis of DCE MRI Data: Insights from Vestibular Schwannoma Responses to Antiangiogenic Therapy in Type II Neurofibromatosis

Li, K.-L., Lewis, D., Zhu, X., Coope, D. J., Djoukhadar, I., King, A. T., Cootes, T. & Jackson, A., 11 Sept 2023, In: Pharmaceuticals. 16, 9, 23 p., 1282.

Research output: Contribution to journal › Article › peer-review

Open Access

Quantitative ΔR1 and PK Mapping Supports Tumor Habitat Delineation and Anti-Angiogenic Response Prediction of Vestibular Schwannoma

Zhu, X., Lewis, D., Li, K.-L., Lloyd, W., Waqar, M., Djoukhadar, I., Coope, D., King, A. T., Cootes, T. & Jackson, A., 3 Jun 2023.

Research output: Contribution to conference › Poster › peer-review

2022

Surrogate vascular input function measurements from the superior sagittal sinus are repeatable and provide tissue-validated kinetic parameters in brain DCE-MRI

Lewis, D., Zhu, X., Coope, D., Zhao, S., King, A., Cootes, T., Jackson, A. & Li, K.-L., 24 May 2022, In: Scientific Reports. 12, 1, 14 p., 8737.

Research output: Contribution to journal › Article › peer-review

Open Access

Visualising spatial heterogeneity in glioblastoma using imaging habitats

Waqar, M., Van Houdt, P. J., Hessen, E., Li, K.-L., Zhu, X., Jackson, A., Iqbal, M., O'Connor, J., Djoukhadar, I., van der Heide, U. A., Coope, D. J. & Borst, G. R., 24 Nov 2022, In: Frontiers in Oncology. 12, p. 1037896 1037896.

Research output: Contribution to journal › Review article › peer-review

Open Access

2021

The LEGATOS technique: A new tissue‐validated dynamic contrast‐enhanced MRI method for whole‐brain, high‐spatial resolution parametric mapping

Li, K.-L., Lewis, D., Coope, D., Roncaroli, F., Agushi, E., Pathmanaban, O., King, A. T., Zhao, S., Jackson, A., Cootes, T. & Zhu, X., 1 Oct 2021, In: Magnetic Resonance in Medicine. 86, 4, p. 2122-2136 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2020

Accuracy assessment of high-spatial resolution whole-brain tracer-kinetic parameter maps generated using dual-temporal resolution DCE-MRI.

Li, K.-L., Lewis, D., Zhao, S., Jackson, A. & Zhu, X., 2020.

Research output: Contribution to conference › Poster › peer-review

A Novel Approach Using First-Pass Adjusted DTR-DCE-MRI (FAD) for Accurate Super-Spatial Resolution Brain Pharmacokinetic Parametric Mapping

Zhu, X., Lewis, D., Zhao, S., Jackson, A. & Li, K.-L., 2020.

Research output: Contribution to conference › Poster › peer-review

The microenvironment in sporadic and neurofibromatosis type II-related vestibular schwannoma: the same tumor or different? A comparative imaging and neuropathology study

Lewis, D., Donofrio, C. A., O'Leary, C., Li, K.-L., Zhu, X., Williams, R., Djoukhadar, I., Agushi, E., Hannan, C. J., Stapleton, E., Lloyd, S. K., Freeman, S. R., Wadeson, A., Rutherford, S. A., Hammerbeck-Ward, C., Evans, D. G., Jackson, A., Pathmanaban, O. N., Roncaroli, F. & King, A. T. & 1 others, Coope, D. J., 29 May 2020, In: Journal of neurosurgery. 134, 5, p. 1419-1429 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Improving quantification accuracy in whole brain high spatial resolution 3D kinetic mapping: Development of a novel dual temporal resolution DCE-MRI technique.

Li, K.-L., Lewis, D., Jackson, A., Zhao, S. & Zhu, X., 2019, The 27th Scientific Meeting of the International Society for Magnetic Resonance in Medicine..

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Inflammation and vascular permeability correlate with growth in sporadic vestibular schwannoma

Lewis, D., Roncaroli, F., Agushi, E., Mosses, D., Williams, R., Li, K.-L., Zhu, X., Hinz, R., Atkinson, R., Wadeson, A., Hulme, S., Mayers, H., Stapleton, E., Lloyd, S. K. L., Freeman, S. R., Rutherford, S. A., Hammerbeck-Ward, C., Evans, D. G., Pathmanaban, O. & Jackson, A. & 2 others, King, A. T. & Coope, D. J., Mar 2019, In: Neuro-Oncology. 21, 3, p. 314-325 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Low Dose T1W DCE-MRI for Early Time Points (ET) Perfusion Measurement in Patients with Intra-Cranial Tumors: A Pilot Study Applying the Microsphere Model to Measure Absolute Cerebral Blood Flow

Li, K.-L., Lewis, D., Jackson, A., Zhao, S. & Zhu, X., 2018, In: Journal of Magnetic Resonance Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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2017

Blood-Brain Barrier Permeability of Normal Appearing White Matter in Patients with Vestibular Schwannoma: A New Hybrid Approach for Analysis of T1W DCE-MRI

Li, K.-L., Zhu, X., Zhao, S. & Jackson, A., 2017, In: Journal of Magnetic Resonance Imaging.

Research output: Contribution to journal › Article › peer-review

Open Access

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225 Downloads (Pure)

2015

A Comparison of [11C]-(R)PK11195 Tracer Kinetics and MRI-Based Vascularity-Related Parameters in Gliomas

Li, C., Su, Z., Li, K.-L., Gerhard, A., Thompson, G., Zhu, X., Hinz, R., Roncaroli, F., Herholz, K. & Jackson, A., 30 May 2015, 2015 Annual Meeting proceedings. ISMRM, p. 4671-4671 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Assessment and Prediction of Vestibular Schwannoma Response to Anti-angiogenic Therapy in Neurofibromatosis Type 2 Patient Using Low Dose High Temporal Resolution DCE-MRI

Li, K., Jackson, A. & Zhu, X., 2015, 2015 Annual Meeting Proceedings. ISMRM, p. 3079-3079 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Vascular biomarkers derived from dynamic contrast-enhanced MRI predict response of vestibular schwannoma to antiangiogenic therapy in type 2 neurofibromatosis.

Li, K.-L., Djoukhadar, I., Zhu, X., Zhao, S., Lloyd, S., Mccabe, M., McBain, C., Evans, G. & Jackson, A., 26 Aug 2015, In: Neuro-Oncology. 18, 2, p. 275-282 7 p., 26311690.

Research output: Contribution to journal › Article › peer-review

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162 Downloads (Pure)

2014

Estimation of R1 changes from Dual bolus DCE-MRI in Vascular Schwannomas and Meningiomas of Patients Undergoing Treatment of Bevacizumab

Zhu, X., Zhao, S., Li, K. & Jackson, A., 10 May 2014, 2014 Annual Meeting Proceedings. ISMRM, p. 4586-4586 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Feasibility of applying dual injection DCE-MRI technique in liver study

Watkins, A., Li, K.-L., Zhu, X. & Jackson, A., 10 May 2014, 2014 Annual Meeting Proceedings. ISMRM, p. 3644-3644 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Semi-Quantitative Parameter Analysis of DCE-MRI Revisited: Monte-Carlo Simulation, Clinical Comparisons, and Clinical Validation of Measurement Errors in Patients with Type 2 Neurofibromatosis

Jackson, A., Li, K.-L. & Zhu, X., Mar 2014, In: P L o S One. 9, 3, p. 1-13 12 p., e90300.

Research output: Contribution to journal › Article › peer-review

2013

Analyzing Error Propagation in Semi-Quantitative DCE MRI Parameters in Brain Tumors: A Comparison Study to Monte Carlo Simulation Predictions

Li, K.-L., Zhu, X. & Jackson, A., Apr 2013, 2013 Annual Meeting Proceedings. ISMRM, p. 3071-3071 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2012

An improved coverage and spatial resolutiona-using dual injection dynamic contrast-enhanced (ICE-DICE) MRI: A novel dynamic contrast-enhanced technique for cerebral tumors

Li, K. L., Buonaccorsi, G., Thompson, G., Cain, J. R., Watkins, A., Russell, D., Qureshi, S., Evans, D. G., Lloyd, S. K., Zhu, X. & Jackson, A., Aug 2012, In: Magnetic Resonance in Medicine. 68, 2, p. 452-462 10 p.

Research output: Contribution to journal › Article › peer-review

2011

Age and Gender Related Alterations in Brain Perfusion Dynamics

Liu, Y., Zhu, X., Feinberg, D., Guenther, M., Rosen, H., Weiner1, M. W. & Schuff, N., 2011, Proc. Intl. Soc. Mag. Reson. Med. 19. p. 779

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Arterial spin labeling MRI study of age and gender effects on brain perfusion hemodynamicsm

Liu, Y., Zhu, X., Feinberg, D., Guenther, M., Gregori, J., Weiner, M. W. & Schuff, N., 2 Dec 2011, In: Magnetic Resonance in Medicine. 0, 0, p. 0-0

Research output: Contribution to journal › Article › peer-review

Improving quantitative accuracy and spatial resolutionof parametric imaging using a dual-temporal resolution DCE-MRI technique

Zhu, X., Li, K.-L., Qureshi, S., Cain, J., Watkins, A., Evans, G., Lloyd, S. & Jackson, A., 2011, Proc. Intl. Soc. Mag. Reson. Med. 19. p. 3119-3119 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Parameter estimation in arterial spin labeling MRI: Comparing the four phase model and the Buxton model with Fourier transform

J, J., Pham, V., Zhu, X. & Li, K.-L., 2011, In: Quantitative Imaging in Medicine and Surgery. 1, 1, p. 17-23 7 p.

Research output: Contribution to journal › Article › peer-review

Separation of Intra- And Extra-Vascular Spaces in Human Brain with DCE-MRI and 11C- Verapamil PET

Zhu, X., Cain, J. R., Wang, S., Feldmann, M., Thompson, G., Li, K.-L., Asselin, M. & Jackson, A., 2011, Proc. Intl. Soc. Mag. Reson. Med. 19. p. 784-784 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

What is the Minimum Time Resolution Required for DCE-MRI Kinetic Analysis with Kety Model Using Single- and Dual-Temporal-Resolution Techniques?

Li, K.-L., Thompson, G., Zhu, X., Buonaccorsi, G. & Jackson, A., 2011, Proc. Intl. Soc. Mag. Reson. Med. 19. p. 3118-3118 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2009

Parameter Estimation in Arterial Spin Labeling MRI: Comparing the Four Phase Model and the Buxton Model with Fourier Transform

Pham, V., Zhu, X., Li, K.-L. & Ji, J. X., 2009, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society. p. 4791-4794 4 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Regional myo-inositol concentration in mild cognitive impairment using 1H magnetic resonance spectroscopic imaging

Siger, M., Schuff, N., Zhu, X., Miller, B. L. & Weiner, M. W., Jan 2009, In: Alzheimer disease and associated disorders. 23, 1, p. 57-62 5 p.

Research output: Contribution to journal › Article › peer-review

Spectrally selective Arterial Spin Labeling Imaging For Breast Cancer Perfusion Study

Li, K.-L., Du, Y., Proctor, E., Zhu, X., Medved, M., Karczmar, G. & Hylton, N., 2009, Proc. Intl. Soc. Mag. Reson. Med. 17. p. 2130-2130 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2008

Developing markers for stratifying patients into good vs. poor prognostic categories using pre-neoadjuvant chemotherapy three time points breast contrast-enhanced MRI and histogram analysis

Li, K., Gibbs, J., Proctor, E., Partridge, S., Zhu, X., Esserman, L. & Hylton, N., 2008, . Intl. Soc. Mag. Reson. Med. 16.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Regional myo-inositol concentration in mild cognitive impairment and Alzheimer disease using 1H, magnetic resonance spectroscopic imaging

Siger, M., Schuff, N., Zhu, X. & Weiner, M., 2008, Proc. Intl. Soc. Mag. Reson. Med. 16. p. 2014-2014 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Voxel-Based DTI Analysis of White Matter Alterations in Parkinson’s Disease

Zhan, W., Kang, G. A., Glass, G. A., Marks, W. J., Zhang, Y., Nezamzadeh, M., Ebel, A., Zhu, X., Millin, R., McCoy, D., Weiner, M. W. & Schuff, N., 2008, Proc. Intl. Soc. Mag. Reson. Med. 16. p. 267-267 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Voxelwise DTI and FLAIR Correlation Analysis for Characterization of White Matter Degeneration

Zhan, W., Zhang, Y., Mueller, S., Lorenzen, P., Hadjidemetriou, E., Zhu, X., Buckley, S., Nezamzadeh, M., Schuff, N. & Weiner, M. W., 2008, Proc. Intl. Soc. Mag. Reson. Med. 16. p. 3543-3543 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2007

Age and Alzheimer’s Disease Related Effects on CBF and ATT of Posterior Cingulate Cortex with dynamic ASL MRI

Zhu, X., Schuff, N., Gunther, M., Feinberg, D., Zhang, Y., Nezamzadeh, M., Jahng, G.-H. & Weiner, M., 2007, Proc. International Prevention of Dementia Conference.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Comparison of cerebral blood volume maps generated from T2* and T1 weighted MRI data in intra-axial cerebral tumours

Haroon, H. A., Patankar, T. F., Zhu, X. P., Li, K. L., Thacker, N. A., Scott, M. J. & Jackson, A., Mar 2007, In: British Journal of Radiology. 80, 951, p. 161-168 7 p.

Research output: Contribution to journal › Article › peer-review

Dynamic Arterial Spin Labeling Perfusion Imaging at 4T Using Parallel Imaging: Effects on Parametric Mapping

Ji, J., Zhu, X., Li, K., Schuff, N., Guenther, M., Feinberg, D. & Weiner, M., 2007, Proc. Intl. Soc. Mag. Reson. Med. 15. p. 1410-1410 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Imaging of mild cognitive impairment and early dementia

Schuff, N. & Zhu, X. P., 2007, In: British Journal of Radiology. 80, 2, p. S109-S114

Research output: Contribution to journal › Article › peer-review

Improved model-based magnetic resonance spectroscopic imaging

Jacob, M., Zhu, X., Ebel, A., Schuff, N. & Liang, Z. P., Oct 2007, In: IEEE Transactions on Medical Imaging. 26, 10, p. 1305-1318 13 p.

Research output: Contribution to journal › Article › peer-review

Kinetic assessment of breast tumors using high spatial resolution signal enhancement ratio (SER) imaging

Li, K.-L., Li, K. L., Henry, R. G., Wilmes, L. J., Gibbs, J., Zhu, X., Lu, Y. & Hylton, N. M., Sept 2007, In: Magnetic Resonance in Medicine. 58, 3, p. 572-581 9 p.

Research output: Contribution to journal › Article › peer-review

Spectral phase-corrected GRAPPA reconstruction of three-dimensional echo-planar spectroscopic imaging (3D-EPSI)

Zhu, X., Ebel, A., Ji, J. X. & Schuff, N., May 2007, In: Magnetic Resonance in Medicine. 57, 5, p. 815-820 5 p.

Research output: Contribution to journal › Article › peer-review

2006

Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging

Maudsley, A. A., Darkazanli, A., Alger, J. R., Hall, L. O., Schuff, N., Studholme, C., Yu, Y., Ebel, A., Frew, A., Goldgof, D., Gu, Y., Pagare, R., Rousseau, F., Sivasankaran, K., Soher, B. J., Weber, P., Young, K. & Zhu, X., Jun 2006, In: NMR in Biomedicine. 19, 4, p. 492-503 11 p.

Research output: Contribution to journal › Article › peer-review

Constrained Spectroscopic Imaging with Hard and Soft Anatomical Boundary Constraints

Haldar, J. P., Jacob, M., Zhu, X., Ebel, A., Schuff, N., Hernando, D., Sutton, B. & Liang, Z.-P., 2006, Proc. Intl. Soc. Mag. Reson. Med. 14. p. 24-24 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-Inositol using magnetic resonance spectroscopic imaging

Zhu, X., Schuff, N., Kornak, J., Soher, B., Yaffe, K., Kramer, J. H., Ezekiel, F., Miller, B. L., Jagust, W. J. & Weiner, M. W., Apr 2006, In: Alzheimer disease and associated disorders. 20, 2, p. 77-85 8 p.

Research output: Contribution to journal › Article › peer-review

Robust analysis of short echo time 1H MRSI of human brain

Zhu, X. P., Young, K., Ebel, A., Sober, B. J., Kaiser, L., Matson, G., Weiner, W. M. & Schuff, N., Mar 2006, In: Magnetic Resonance in Medicine. 55, 3, p. 706-711 5 p.

Research output: Contribution to journal › Article › peer-review

Sensitivity Encoded Three Dimensional Echo Planar Spectroscopic Imaging (3D-EPSI) of Human Brain at 4T

Zhu, X., Ebel, A., Ji, J. X., Weiner, M. W. & Schuff, N., 2006, Intl. Soc. Mag. Reson. Med. 14. p. 3075-3075 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2005

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology: Dynamic Contrast-Enhanced MRI in Cerebral Tumors

Zhu, X.-P., Li, K.-L. & Jackson, A., 2005, 1 ed. Berlin, Heidelberg: Springer Nature.

Research output: Book/Report › Book › peer-review

Four-phase single-capillary stepwise model for kinetics in arterial spin labeling MRI

Li, K. L., Zhu, X., Hylton, N., Jahng, G. H., Weiner, M. W. & Schuff, N., Mar 2005, In: Magnetic Resonance in Medicine. 53, 3, p. 511-518 7 p.

Research output: Contribution to journal › Article › peer-review

Human brain: Reliability and reproducibility of pulsed arterial spin-labeling perfusion MR imaging

Jahng, G. H., Song, E., Zhu, X. P., Matson, G. B., Weiner, M. W. & Schuff, N., Mar 2005, In: Radiology. 234, 3, p. 909-916 7 p.

Research output: Contribution to journal › Article › peer-review

New Spectral Analysis of Short Echotime Multislice 1H MRSI in Human Brain using Eigen Spectra, Baseline Correction and Frequency Alignment

Zhu, X., Young, K., Soher, B., Yin, H., Ezekiel, F., Weiner, M. & Schuff, N., 2005, Proc. Intl. Soc. Mag. Reson. Med. 13. p. 55-55 1 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Xiaoping Zhu, PhD, MD

Research output

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