Biological rhythms

Circadian rhythms pervades all aspects of our physiology and behaviour, from the timing of our sleep-wake cycle and feeding habits to organising metabolic processes, neuroendocrine signalling, and cognition.

This daily timing is orchestrated by a master circadian clock within the brain which coordinates circadian signals across a multitude of clocks in the retina, brain, and body.

Our researchers are using vertebrate and invertebrate models combined with state-of-the-art methods in electrophysiology, imaging, and computational modelling to figure out the mechanisms that operate to provide us with this daily sense of time.