Sleep and Rheumatoid Arthritis Health Related Quality of Life: The Sleep - RA Study.

Project Details


People with rheumatoid arthritis (RA) frequently report reduced health-related quality of life (HRQoL), the impact one’s health has on physical, emotional and social well-being. There are likely numerous causes for poor HRQol, but people with RA have identified sleep disturbances as a key contributor to their well-being.

This prospective cohort study will recruit 350 people with RA, aged 18 years or older. Following completion of a baseline questionnaire, participants will record data on 10 symptoms including pain, fatigue, and mood twice-daily for 30 days using a study-specific mobile application (app). A tri-axial accelerometer will continuously record daytime activity and estimate evening sleep parameters over the 30 days. Every 10 days following study initiation participants will complete a questionnaire that measures disease specific (Arthritis Impact Measurement Scale 2 - Short Form (AIMS2-SF)) and generic (WHOQOL-BREF) quality of life. A final questionnaire will be completed 60 days after entering the study. Structural equation modelling (SEM) and latent trajectory models (LTM) will test the relationship between circadian rest/activity rhythms and HRQoL over time.

Key findings

Currently recruiting
Short titleR:KAE McBJ3
Effective start/end date4/04/163/10/19

Collaborative partners

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 16 - Peace, Justice and Strong Institutions


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.