β-Carotene with vitamins E and C offers synergistic cell protection against NO(x)

F. Böhm; R. Edge; D. J. McGarvey; T. G. Truscott

doi:10.1016/S0014-5793(98)01173-9

β-Carotene with vitamins E and C offers synergistic cell protection against NO(x)

F. Böhm, R. Edge, D. J. McGarvey, T. G. Truscott^*

^*Corresponding author for this work

Dalton Nuclear Institute

Research output: Contribution to journal › Article › peer-review

Abstract

The peroxynitrite anion and the nitrogen dioxide (radical) are important toxic species which can arise in vivo from nitric oxide. Both in vivo and in vitro cell protection is demonstrated for β-carotene in the presence of vitamin E and vitamin C. A synergistic protection is observed compared to the individual anti-oxidants and this is explained in terms of an electron transfer reaction in which the β-carotene radical is repaired by vitamin C. Copyright (C) 1998 Federation of European Biochemical Societies.

Original language	English
Pages (from-to)	387-389
Number of pages	3
Journal	FEBS Letters
Volume	436
Issue number	3
DOIs	https://doi.org/10.1016/S0014-5793(98)01173-9
Publication status	Published - 9 Oct 1998

Keywords

β-Carotene
Lymphocyte
Nitrogen dioxide
Peroxynitrite
Vitamin C
Vitamin E

Research Beacons, Institutes and Platforms

Dalton Nuclear Institute

Access to Document

10.1016/S0014-5793(98)01173-9

Cite this

@article{3aac65e7e15d46bcb58d581e40b62555,

title = "β-Carotene with vitamins E and C offers synergistic cell protection against NO(x)",

abstract = "The peroxynitrite anion and the nitrogen dioxide (radical) are important toxic species which can arise in vivo from nitric oxide. Both in vivo and in vitro cell protection is demonstrated for β-carotene in the presence of vitamin E and vitamin C. A synergistic protection is observed compared to the individual anti-oxidants and this is explained in terms of an electron transfer reaction in which the β-carotene radical is repaired by vitamin C. Copyright (C) 1998 Federation of European Biochemical Societies.",

keywords = "β-Carotene, Lymphocyte, Nitrogen dioxide, Peroxynitrite, Vitamin C, Vitamin E",

author = "F. B{\"o}hm and R. Edge and McGarvey, {D. J.} and Truscott, {T. G.}",

year = "1998",

month = oct,

day = "9",

doi = "10.1016/S0014-5793(98)01173-9",

language = "English",

volume = "436",

pages = "387--389",

journal = "FEBS Letters",

issn = "0014-5793",

publisher = "John Wiley & Sons Ltd",

number = "3",

}

TY - JOUR

T1 - β-Carotene with vitamins E and C offers synergistic cell protection against NO(x)

AU - Böhm, F.

AU - Edge, R.

AU - McGarvey, D. J.

AU - Truscott, T. G.

PY - 1998/10/9

Y1 - 1998/10/9

N2 - The peroxynitrite anion and the nitrogen dioxide (radical) are important toxic species which can arise in vivo from nitric oxide. Both in vivo and in vitro cell protection is demonstrated for β-carotene in the presence of vitamin E and vitamin C. A synergistic protection is observed compared to the individual anti-oxidants and this is explained in terms of an electron transfer reaction in which the β-carotene radical is repaired by vitamin C. Copyright (C) 1998 Federation of European Biochemical Societies.

AB - The peroxynitrite anion and the nitrogen dioxide (radical) are important toxic species which can arise in vivo from nitric oxide. Both in vivo and in vitro cell protection is demonstrated for β-carotene in the presence of vitamin E and vitamin C. A synergistic protection is observed compared to the individual anti-oxidants and this is explained in terms of an electron transfer reaction in which the β-carotene radical is repaired by vitamin C. Copyright (C) 1998 Federation of European Biochemical Societies.

KW - β-Carotene

KW - Lymphocyte

KW - Nitrogen dioxide

KW - Peroxynitrite

KW - Vitamin C

KW - Vitamin E

UR - http://www.scopus.com/inward/record.url?scp=0242644199&partnerID=8YFLogxK

U2 - 10.1016/S0014-5793(98)01173-9

DO - 10.1016/S0014-5793(98)01173-9

M3 - Article

C2 - 9801154

AN - SCOPUS:0242644199

SN - 0014-5793

VL - 436

SP - 387

EP - 389

JO - FEBS Letters

JF - FEBS Letters

IS - 3

ER -

β-Carotene with vitamins E and C offers synergistic cell protection against NO(x)

Abstract

Keywords

Research Beacons, Institutes and Platforms

Access to Document

Other files and links

Fingerprint

Cite this